8AU0: A1 luminal coiled-coil domain of SUN1

Crystal structure of the a1 luminal coiled-coil domain of SUN1. Determined by X-ray diffraction at 2.07 Å resolution. Released 19 Jul 2023.

Method: X-ray diffraction
Resolution: 2.07 Å
Organism: Homo sapiens
Chains: 3
Atoms: 1,008
Mol. weight: 13.96 kDa
Released: 19 Jul 2023

Explore 8AU0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8AU0 contains 3 α-helices and 0 β-strands across 3 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	362-399	38

Chains B and C: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	362-400	39

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
SUN domain-containing protein 1	A, B, C	protein	42	Homo sapiens	O94901 (AlphaFold model)

Sequence of entity 1 (A, B, C), FASTA

>8AU0_1 SUN domain-containing protein 1 (chains A, B, C)
GSMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQME

Primary citation

Molecular insights into LINC complex architecture through the crystal structure of a luminal trimeric coiled-coil domain of SUN1. Gurusaran, M., Biemans, J.J., Wood, C.W. et al. Front Cell Dev Biol (2023) 11:1144277-1144277. DOI 10.3389/fcell.2023.1144277 · PubMed

Other PDB entries of the same protein (UniProt O94901 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6R2I 1.54 Å, Crystal structure of the SUN1-KASH5 6:6 complex
8B46 1.67 Å, Crystal structure of the SUN1-KASH6 9:9 complex
6R15 1.82 Å, Crystal structure of the SUN1-KASH1 6:6 complex
8B5X 1.98 Å, Crystal structure of the SUN1-KASH6 9:6 complex
7Z8Y 2.29 Å, Crystal structure of the SUN1-KASH6 9:6 complex
6R16 2.75 Å, Crystal structure of the SUN1-KASH4 6:6 complex
7E34 3.19 Å, Crystal structure of SUN1-Speedy A-CDK2

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