8DQW: Open state of Rad24-RFC:9-1-1
Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction. Determined by electron microscopy at 2.1 Å resolution. Released 17 Aug 2022.
- Method
- Electron microscopy
- Resolution
- 2.1 Å
- Organism
- Saccharomyces cerevisiae
- Chains
- 10
- Atoms
- 23,629
- Mol. weight
- 437.15 kDa
- Ligands
- MG, AGS, GDP
- Released
- 17 Aug 2022
Explore 8DQW in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8DQW contains 178 α-helices and 112 β-strands across 8 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A: 31 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 66-69 | 4 | |
| α-helix | 75-77 | 3 | |
| α-helix | 82-95 | 14 | |
| β-strand | 104-109 | 6 | 23 |
| α-helix | 115-130 | 16 | |
| α-helix | 132-134 | 3 | |
| β-strand | 140 | 1 | 18 |
| β-strand | 148-150 | 3 | 23 |
| α-helix | 162-164 | 3 | |
| α-helix | 165-173 | 9 | |
| α-helix | 178-180 | 3 | |
| β-strand | 183-186 | 4 | 23 |
| α-helix | 195-209 | 15 | |
| β-strand | 219-224 | 6 | 23 |
| β-strand | 226-227 | 2 | 24 |
| α-helix | 239-242 | 4 | |
| β-strand | 243-244 | 2 | 24 |
| α-helix | 246-249 | 4 | |
| α-helix | 252-255 | 4 | |
| β-strand | 260-264 | 5 | 23 |
| α-helix | 267-269 | 3 | |
| α-helix | 270-283 | 14 | |
| α-helix | 285-290 | 6 | |
| α-helix | 297-307 | 11 | |
| α-helix | 311-322 | 12 | |
| α-helix | 336-338 | 3 | |
| α-helix | 339-348 | 10 | |
| α-helix | 356-366 | 11 | |
| α-helix | 368-372 | 5 | |
| α-helix | 374-383 | 10 | |
| α-helix | 384-389 | 6 | |
| α-helix | 394-407 | 14 | |
| α-helix | 414-430 | 17 | |
| α-helix | 446-471 | 26 | |
| α-helix | 477-479 | 3 | |
| α-helix | 480-484 | 5 | |
| α-helix | 485-508 | 24 | |
| α-helix | 565-590 | 26 | |
| α-helix | 599-603 | 5 | |
Chain B: 26 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 11-14 | 4 | |
| α-helix | 20-22 | 3 | |
| α-helix | 27-39 | 13 | |
| α-helix | 42-44 | 3 | |
| β-strand | 45-48 | 4 | 1 |
| α-helix | 55-67 | 13 | |
| α-helix | 68-70 | 3 | |
| α-helix | 71-74 | 4 | |
| β-strand | 75-78 | 4 | 1 |
| α-helix | 86-88 | 3 | |
| α-helix | 89-93 | 5 | |
| α-helix | 94-98 | 5 | |
| β-strand | 109-114 | 6 | 1 |
| α-helix | 116-118 | 3 | |
| α-helix | 121-134 | 14 | |
| β-strand | 138-144 | 7 | 1 |
| α-helix | 147-149 | 3 | |
| α-helix | 152-155 | 4 | |
| β-strand | 159-162 | 4 | 1 |
| α-helix | 163-167 | 5 | |
| α-helix | 168-182 | 15 | |
| β-strand | 186 | 1 | 2 |
| α-helix | 188-198 | 11 | |
| α-helix | 202-216 | 15 | |
| β-strand | 219 | 1 | 2 |
| α-helix | 221-227 | 7 | |
| α-helix | 232-241 | 10 | |
| α-helix | 245-251 | 7 | |
| α-helix | 252-256 | 5 | |
| α-helix | 257-259 | 3 | |
| α-helix | 263-275 | 13 | |
| α-helix | 282-300 | 19 | |
| α-helix | 306-320 | 15 | |
Chain C: 25 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-12 | 3 | |
| α-helix | 15-18 | 4 | |
| α-helix | 24-26 | 3 | |
| α-helix | 31-43 | 13 | |
| β-strand | 49-52 | 4 | 3 |
| α-helix | 59-71 | 13 | |
| α-helix | 72-77 | 6 | |
| β-strand | 79-82 | 4 | 3 |
| α-helix | 90-92 | 3 | |
| α-helix | 93-97 | 5 | |
| α-helix | 98-101 | 4 | |
| β-strand | 103 | 1 | 4 |
| β-strand | 112-116 | 5 | 3 |
| α-helix | 119-121 | 3 | |
| α-helix | 124-136 | 13 | |
| β-strand | 141-147 | 7 | 3 |
| α-helix | 150-152 | 3 | |
| α-helix | 155-160 | 6 | |
| β-strand | 162-165 | 4 | 3 |
| α-helix | 167-170 | 4 | |
| α-helix | 171-184 | 14 | |
| β-strand | 188-189 | 2 | 5 |
| α-helix | 191-201 | 11 | |
| α-helix | 205-218 | 14 | |
| α-helix | 225 | 1 | |
| β-strand | 226-227 | 2 | 5 |
| α-helix | 229-236 | 8 | |
| α-helix | 238-240 | 3 | |
| α-helix | 241-253 | 13 | |
| α-helix | 256-270 | 15 | |
| α-helix | 274-286 | 13 | |
| α-helix | 293-311 | 19 | |
| α-helix | 316-331 | 16 | |
Chain D: 30 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 22-24 | 3 | |
| α-helix | 27-30 | 4 | |
| α-helix | 36-38 | 3 | |
| α-helix | 43-55 | 13 | |
| α-helix | 58-60 | 3 | |
| β-strand | 61-64 | 4 | 6 |
| α-helix | 71-82 | 12 | |
| α-helix | 88-91 | 4 | |
| β-strand | 92-95 | 4 | 6 |
| α-helix | 103-105 | 3 | |
| α-helix | 106-110 | 5 | |
| α-helix | 111-115 | 5 | |
| β-strand | 116 | 1 | 7 |
| α-helix | 117-122 | 6 | |
| α-helix | 123-128 | 6 | |
| β-strand | 135-139 | 5 | 6 |
| α-helix | 142-144 | 3 | |
| α-helix | 147-151 | 5 | |
| α-helix | 154-159 | 6 | |
| β-strand | 164-170 | 7 | 6 |
| α-helix | 173-175 | 3 | |
| α-helix | 178-183 | 6 | |
| β-strand | 185-188 | 4 | 6 |
| α-helix | 189-191 | 3 | |
| β-strand | 192 | 1 | 8 |
| α-helix | 198-207 | 10 | |
| β-strand | 212 | 1 | 9 |
| α-helix | 216-224 | 9 | |
| β-strand | 226 | 1 | 8 |
| α-helix | 228-245 | 18 | |
| α-helix | 249-250 | 2 | |
| β-strand | 251 | 1 | 9 |
| α-helix | 253-260 | 8 | |
| α-helix | 262-264 | 3 | |
| α-helix | 265-277 | 13 | |
| α-helix | 280-290 | 11 | |
| α-helix | 291-293 | 3 | |
| α-helix | 297-309 | 13 | |
| α-helix | 316-334 | 19 | |
| α-helix | 339-351 | 13 | |
Chain E: 24 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-7 | 4 | |
| α-helix | 13-15 | 3 | |
| α-helix | 20-31 | 12 | |
| α-helix | 33-35 | 3 | |
| α-helix | 36-38 | 3 | |
| β-strand | 39-42 | 4 | 10 |
| α-helix | 49-60 | 12 | |
| α-helix | 63-66 | 4 | |
| β-strand | 69-76 | 8 | 10 |
| β-strand | 82-90 | 9 | 10 |
| β-strand | 93-96 | 4 | 10 |
| α-helix | 98-104 | 7 | |
| α-helix | 105-108 | 4 | |
| α-helix | 109-113 | 5 | |
| α-helix | 114-118 | 5 | |
| β-strand | 122-124 | 3 | 11 |
| β-strand | 131-133 | 3 | 11 |
| β-strand | 136-140 | 5 | 10 |
| α-helix | 143-145 | 3 | |
| α-helix | 148-160 | 13 | |
| β-strand | 165-171 | 7 | 10 |
| α-helix | 179-183 | 5 | |
| β-strand | 186-189 | 4 | 10 |
| α-helix | 191-194 | 4 | |
| α-helix | 195-209 | 15 | |
| β-strand | 212-213 | 2 | 12 |
| α-helix | 217-226 | 10 | |
| α-helix | 230-243 | 14 | |
| β-strand | 247-248 | 2 | 12 |
| α-helix | 253-255 | 3 | |
| α-helix | 258-272 | 15 | |
| α-helix | 276-291 | 16 | |
| α-helix | 296-308 | 13 | |
| α-helix | 315-334 | 20 | |
| α-helix | 338-353 | 16 | |
Chain F: 15 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 11-15 | 5 | 13 |
| α-helix | 18-28 | 11 | |
| α-helix | 29-31 | 3 | |
| β-strand | 36-42 | 7 | 14 |
| β-strand | 45-52 | 8 | 14 |
| β-strand | 56-63 | 8 | 14 |
| α-helix | 64-66 | 3 | |
| β-strand | 69-72 | 4 | 13 |
| β-strand | 79-85 | 7 | 14 |
| α-helix | 86-96 | 11 | |
| α-helix | 97-99 | 3 | |
| β-strand | 105-110 | 6 | 13 |
| α-helix | 116 | 1 | |
| β-strand | 117-122 | 6 | 13 |
| β-strand | 126-132 | 7 | 13 |
| β-strand | 135 | 1 | 7 |
| α-helix | 136-138 | 3 | |
| α-helix | 142-144 | 3 | |
| β-strand | 152-159 | 8 | 14 |
| α-helix | 160-172 | 13 | |
| β-strand | 177-184 | 8 | 15 |
| β-strand | 190-198 | 9 | 15 |
| β-strand | 201-207 | 7 | 15 |
| β-strand | 214-219 | 6 | 14 |
| α-helix | 231 | 1 | |
| β-strand | 232-238 | 7 | 15 |
| α-helix | 239-242 | 4 | |
| α-helix | 243-245 | 3 | |
| α-helix | 246-251 | 6 | |
| β-strand | 254-260 | 7 | 14 |
| β-strand | 264-270 | 7 | 14 |
| β-strand | 305-311 | 7 | 14 |
| α-helix | 312 | 1 | |
| β-strand | 313 | 1 | 4 |
| α-helix | 318-328 | 11 | |
Chain G: 13 helices, 25 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 3-7 | 5 | 15 |
| α-helix | 10-26 | 17 | |
| β-strand | 29-34 | 6 | 16 |
| β-strand | 38-44 | 7 | 16 |
| β-strand | 50-57 | 8 | 16 |
| α-helix | 58-60 | 3 | |
| β-strand | 63-66 | 4 | 15 |
| α-helix | 68-70 | 3 | |
| α-helix | 75-77 | 3 | |
| β-strand | 78-82 | 5 | 16 |
| β-strand | 88-97 | 10 | 16 |
| α-helix | 98-105 | 8 | |
| α-helix | 107-108 | 2 | |
| β-strand | 113-120 | 8 | 15 |
| β-strand | 133 | 1 | 17 |
| β-strand | 134-140 | 7 | 15 |
| β-strand | 145-148 | 4 | 15 |
| β-strand | 151 | 1 | 17 |
| β-strand | 153-155 | 3 | 16 |
| β-strand | 160 | 1 | 18 |
| α-helix | 162-174 | 13 | |
| α-helix | 189-204 | 16 | |
| α-helix | 223-225 | 3 | |
| β-strand | 228-233 | 6 | 16 |
| α-helix | 234-242 | 9 | |
| β-strand | 251-256 | 6 | 19 |
| β-strand | 260-267 | 8 | 19 |
| β-strand | 270-271 | 2 | 20 |
| β-strand | 277-279 | 3 | 20 |
| β-strand | 282-289 | 8 | 19 |
| β-strand | 295-297 | 3 | 16 |
| β-strand | 320-325 | 6 | 19 |
| α-helix | 327-332 | 6 | |
| α-helix | 336-338 | 3 | |
| β-strand | 348-353 | 6 | 16 |
| β-strand | 360-366 | 7 | 16 |
| β-strand | 369-375 | 7 | 16 |
| α-helix | 376-378 | 3 | |
Chain H: 14 helices, 23 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 3-7 | 5 | 21 |
| α-helix | 13-29 | 17 | |
| β-strand | 32-37 | 6 | 21 |
| β-strand | 41-46 | 6 | 21 |
| α-helix | 53-56 | 4 | |
| α-helix | 58-62 | 5 | |
| β-strand | 67-73 | 7 | 21 |
| α-helix | 74-76 | 3 | |
| β-strand | 80-82 | 3 | 21 |
| α-helix | 87-89 | 3 | |
| β-strand | 91-96 | 6 | 21 |
| α-helix | 97-113 | 17 | |
| β-strand | 119-124 | 6 | 21 |
| β-strand | 153-161 | 9 | 21 |
| β-strand | 202-205 | 4 | 21 |
| β-strand | 208-211 | 4 | 21 |
| α-helix | 214-218 | 5 | |
| β-strand | 231-234 | 4 | 21 |
| α-helix | 235-237 | 3 | |
| α-helix | 243-251 | 9 | |
| α-helix | 252-255 | 4 | |
| β-strand | 261-268 | 8 | 13 |
| β-strand | 279-285 | 7 | 13 |
| β-strand | 291-296 | 6 | 13 |
| β-strand | 301 | 1 | 21 |
| β-strand | 393-394 | 2 | 11 |
| α-helix | 395-396 | 2 | |
| α-helix | 398-400 | 3 | |
| β-strand | 405-411 | 7 | 13 |
| α-helix | 412-424 | 13 | |
| β-strand | 427-433 | 7 | 21 |
| β-strand | 437-444 | 8 | 21 |
| β-strand | 447 | 1 | 22 |
| β-strand | 458 | 1 | 22 |
| α-helix | 460-461 | 2 | |
| β-strand | 462-469 | 8 | 21 |
| β-strand | 472 | 1 | 13 |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Replication factor C subunit 4 | B | protein | 323 | Saccharomyces cerevisiae | P40339 (AlphaFold model) |
| Replication factor C subunit 3 | C | protein | 340 | Saccharomyces cerevisiae | P38629 (AlphaFold model) |
| Replication factor C subunit 2 | D | protein | 353 | Saccharomyces cerevisiae | P40348 (AlphaFold model) |
| Replication factor C subunit 5 | E | protein | 354 | Saccharomyces cerevisiae | P38251 (AlphaFold model) |
| DNA damage checkpoint control protein RAD17 | F | protein | 401 | Saccharomyces cerevisiae | P48581 |
| DDC1 isoform 1 | G | protein | 646 | Saccharomyces cerevisiae | Q08949 |
| DNA damage checkpoint control protein MEC3 | H | protein | 474 | Saccharomyces cerevisiae | Q02574 |
| RAD24 isoform 1 | A | protein | 696 | Saccharomyces cerevisiae | P32641 |
| DNA (50-mer) | J | DNA | 70 | Saccharomyces cerevisiae | |
| DNA (5'-d(p*cp*gp*tp*cp*cp*cp*tp*tp*cp*c)-3') | I | DNA | 20 | Saccharomyces cerevisiae | |
Sequence of entity 1 (B), FASTA
>8DQW_1 Replication factor C subunit 4 (chains B)
MSKTLSLQLPWVEKYRPQVLSDIVGNKETIDRLQQIAKDGNMPHMIISGMPGIGKTTSVH
CLAHELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQKKLHLPPGKHKIVILDEADSMT
AGAQQALRRTMELYSNSTRFAFACNQSNKIIEPLQSRCAILRYSKLSDEDVLKRLLQIIK
LEDVKYTNDGLEAIIFTAEGDMRQAINNLQSTVAGHGLVNADNVFKIVDSPHPLIVKKML
LASNLEDSIQILRTDLWKKGYSSIDIVTTSFRVTKNLAQVKESVRLEMIKEIGLTHMRIL
EGVGTYLQLASMLAKIHKLNNKA
Sequence of entity 2 (C), FASTA
>8DQW_2 Replication factor C subunit 3 (chains C)
MSTSTEKRSKENLPWVEKYRPETLDEVYGQNEVITTVRKFVDEGKLPHLLFYGPPGTGKT
STIVALAREIYGKNYSNMVLELNASDDRGIDVVRNQIKDFASTRQIFSKGFKLIILDEAD
AMTNAAQNALRRVIERYTKNTRFCVLANYAHKLTPALLSRCTRFRFQPLPQEAIERRIAN
VLVHEKLKLSPNAEKALIELSNGDMRRVLNVLQSCKATLDNPDEDEISDDVIYECCGAPR
PSDLKAVLKSILEDDWGTAHYTLNKVRSAKGLALIDLIEGIVKILEDYELQNEETRVHLL
TKLADIEYSISKGGNDQIQGSAVIGAIKASFENETVKANV
Sequence of entity 3 (D), FASTA
>8DQW_3 Replication factor C subunit 2 (chains D)
MFEGFGPNKKRKISKLAAEQSLAQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPH
MLFYGPPGTGKTSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNFARLTVSK
PSKHDLENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGVTRFCLICNYVTRIIDPL
ASRCSKFRFKALDASNAIDRLRFISEQENVKCDDGVLERILDISAGDLRRGITLLQSASK
GAQYLGDGKNITSTQVEELAGVVPHDILIEIVEKVKSGDFDEIKKYVNTFMKSGWSAASV
VNQLHEYYITNDNFDTNFKNQISWLLFTTDSRLNNGTNEHIQLLNLLVKISQL
Sequence of entity 4 (E), FASTA
>8DQW_4 Replication factor C subunit 5 (chains E)
MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRCMALLESI
FGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGNNDRIVIQELLKEVAQME
QVDFQDSKDGLAHRYKCVIINEANSLTKDAQAALRRTMEKYSKNIRLIMVCDSMSPIIAP
IKSRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESM
ALNNELALKSSSPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIIL
KELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMCCLD
Sequence of entity 5 (F), FASTA
>8DQW_5 DNA damage checkpoint control protein RAD17 (chains F)
MRINSELANKFSASTVHLEHITTALSCLTPFGSKDDVLIFIDADGLSFVRENNHVIKIQL
LLSRELFMSYSYRNETEDHMKLCVKINHILDSVSVMNRNSDDIVECTLSYDGHGSPFVLI
FEDSFISERVEYSTYLIKDFDTNGLELDRERISFEAIIKGEALHSALKDLKEIGCKECYV
YAKTEANDENVFALISKSQLGFSKIKLPSNRSILEKLQVFDGDSTTVIDGFAVIGFFDFT
SFDKIRKSTKIASKVLFRMDVHGVLSVNILSQTDDVIITDTTRPSNNRPGSIRQLQLPKD
YPGIVIEVCMLEKESIDEAAQTEIELLMETNELGNRNSFKKSTIRKRYGTDKGNETSNDN
LLQLNGKKIKLPSEEENNKNRESEDEENHCKYPTKDIPIFF
Sequence of entity 6 (G), FASTA
>8DQW_6 DDC1 isoform 1 (chains G)
MDYKDDDDKDYKDDDDKDYKDDDDKLEVLFQGPGMSFKATITESGKQNIWFRAIYVLSTI
QDDIKITVTTNELIAWSMNETDTTLCQVRFQKSFFEEYEFKPHEIVFGENGVQVIEDTYG
NSHKLYSFRVNGRHLTTISRKPDGDGIKSFTIAVNNTSTCPESLANRLIVVIEMDSLIVK
EYCPQFQPIKYDPIIINLKYKRRFLDVFGTAASDRNPQEPLDPKLLDVFTNTERELTSAL
FNEEVESDIRKRNQLTAADEINYICCNSTLLKNFLDNCNVNVTDEVKLEINVHRLSITAF
TKAVYGKNNDLLRNALSMSNTISTLDLEHYCLFTTIEDEKQDKRSHSKRREHMKSIIFKL
KDFKNFITIGPSWKTTQDGNDNISLWFCHPGDPILMQMQKPGVKLELVEVTDSNINDDIL
EGKFIKTAISGSKEEAGLKDNKESCESPLKSKTALKRENLPHSVAGTRNSPLKVSYLTPD
NGSTVAKTYRNNTARKLFVEEQSQSTNYEQDKRFRQASSVHMNMNREQSFDIGTTHEVAC
PRNESNSLKRSIADICNETEDPTQQSTFAKRADTTVTWGKALPAADDEVSCSNIDRKGML
KKEKLKHMQGLLNSQNDTSNHKKQDNKEMEDGLGLTQVEKPRGIFD
Sequence of entity 7 (H), FASTA
>8DQW_7 DNA damage checkpoint control protein MEC3 (chains H)
MKLKLIVNGCEAPDDYKLLRTTINTVASLRKTAILRFNSERLTIISTPKSSLNSSNNGTI
LRGDTGQLWCTIPHDVFRLYTVISARELNTITMECNCDSLLSVFKRYDRVMNQGSSSNMT
IKLQSMPEWNTNNGTLSGGTAGGVDTTSKPNPICALGITFEEIVHTSGPNDAIVMNGGVD
EHNGLPTTVGTGNLLASNKVIMHSFKVPVKLLFRAQDTRIQEPMINYIQLMMYKLPPISG
EFGSAFHGFIRRVERYSNVNHIHLMGVKKKEHGNEGDDVELKIIVNELDWHLEICWNGPL
DSVIQRQEGLTDNPSQNQHIDTDGRQEEGSLPIIEADKPMSSLYTNTRDREMEENIRYDE
DLLRIEDSSIADTRGNIYTADTSGDTEFNDISVMVEKAEQESSSTHEVIIRCKDWKVCSK
LYAAFEEVVLAISHDESCVFHCSLDRGSLEDSEDVEKPRERGQIIYYIARSKGL
Sequence of entity 8 (A), FASTA
>8DQW_8 RAD24 isoform 1 (chains A)
MDSTNLNKRPLLQYSLSSLGSQITKWSSSRPTSPVRKARSTENDFLSKQDTSSILPSIND
DGGEQWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHRILLLSGPSGCSKSTVIK
ELSKILVPKYRQNSNGTSFRSTPNEHKVTEFRGDCIVNDLPQMESFSEFLKGARYLVMSN
LSLILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICITECEIPENDNNYRKFGI
DYTFSAETIMNKEILMHPRLKRIKFNPINSTLLKKHLKFICVQNMKMLKEKNKWNKRQEV
IDYIAQETGDIRSAITTLQFWATSSGSLPISTRESTISYFHAIGKVIHGSHSTNNDNEMI
NNLFENSNNLLSKEDFKLGILENYNTFNKGEFSISDASSIVDCLSECDNMNGLPESNEYG
LREVRKTFRNISKQGHNHGTVYFPREWKVRKLQNSFKVQAEDWLNVSLYKYNAVHSFRNI
TLEFGYYAPLIRKCQSYKKKYILYYLKNLPSGSSGPKQTMDKFSDIMKVENGIDVVDRIG
GPIEALSVEDGLAPLMDNDSNNCDHLEDQKKERDRRLRMLIDQYERNVMMANDDLEDEET
SFNDDPIVDSDSDNSNNIGNETFGRSDEDESLCEILSQRQPRKAPVISESLSDSDLEILG
LNLEVLFQGPGGDYKDDDDKDYKDDDDKDYKDDDDK
Sequence of entity 9 (J), FASTA
>8DQW_9 DNA (50-MER) (chains J)
GGACGAGTCAGGAAGGAGCGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTT
Sequence of entity 10 (I), FASTA
>8DQW_10 DNA (5'-D(P*CP*GP*TP*CP*CP*CP*TP*TP*CP*C)-3') (chains I)
CGCTCCTTCCTGACTCGTCC
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| MG | Magnesium ion | Mg | 4 |
| AGS | Phosphothiophosphoric acid-adenylate ester | C10 H16 N5 O12 P3 S | 4 |
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 1 |
Primary citation
Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Schrecker, M., Castaneda, J.C., Devbhandari, S. et al. Elife (2022) 11. DOI 10.7554/eLife.78253 · PubMed
Other PDB entries of the same protein (UniProt P40339 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8DQX 2.1 Å, Open state of RFC:PCNA bound to a 3' ss/dsDNA junction
- 8DR1 2.14 Å, Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2)
- 7ST9 2.2 Å, Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction
- 8DR3 2.2 Å, Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD
- 8DR6 2.39 Å, Closed state of RFC:PCNA bound to a nicked dsDNA
- 8DR0 2.42 Å, Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction
- 8DR4 2.45 Å, Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD
- 9PEO 2.57 Å, Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed…
- 9PER 2.57 Å, Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed…
- 9PET 2.57 Å, Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed…
- 9PES 2.59 Å, Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed…
- 9PEU 2.62 Å, Structure of the S. cerevisiae clamp loader Replication Factor C (RFC) with mixed…
Browse structure collections
About this viewer
MolViewer shows 8DQW directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.