8P2K: 60S ribosomal protein L8
Ternary complex of translating ribosome, NAC and METAP1. Determined by electron microscopy at 2.9 Å resolution. Released 19 Jul 2023.
- Method
- Electron microscopy
- Resolution
- 2.9 Å
- Organisms
- Oryctolagus cuniculus, Homo sapiens
- Chains
- 88
- Atoms
- 231,486
- Mol. weight
- 3984.43 kDa
- Ligands
- N, SPD, SPM, MG
- Released
- 19 Jul 2023
Explore 8P2K in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8P2K contains 618 α-helices and 602 β-strands across 81 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain Aa: 11 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 24-27 | 4 | |
| β-strand | 28-34 | 7 | 87 |
| β-strand | 43-50 | 8 | 87 |
| α-helix | 51-52 | 2 | |
| β-strand | 53 | 1 | 88 |
| β-strand | 56 | 1 | 88 |
| α-helix | 58-62 | 5 | |
| β-strand | 66-70 | 5 | 87 |
| α-helix | 71-73 | 3 | |
| β-strand | 82-92 | 11 | 87 |
| β-strand | 95-105 | 11 | 87 |
| α-helix | 107-113 | 7 | |
| β-strand | 118 | 1 | 89 |
| β-strand | 120-128 | 9 | 87 |
| β-strand | 134-143 | 10 | 87 |
| α-helix | 144-146 | 3 | |
| β-strand | 154 | 1 | 89 |
| α-helix | 158-177 | 20 | |
| α-helix | 181-186 | 6 | |
| α-helix | 192-200 | 9 | |
| β-strand | 207-219 | 13 | 87 |
| α-helix | 221-223 | 3 | |
| α-helix | 225-232 | 8 | |
Chain AA: 3 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-17 | 6 | |
| β-strand | 32-36 | 5 | 2 |
| β-strand | 43-47 | 5 | 2 |
| β-strand | 55 | 1 | 3 |
| β-strand | 62 | 1 | 3 |
| β-strand | 64-65 | 2 | 4 |
| α-helix | 71 | 1 | |
| β-strand | 72-73 | 2 | 4 |
| α-helix | 74 | 1 | |
| β-strand | 78-81 | 4 | 2 |
Chain Ab: 11 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 58-60 | 3 | |
| α-helix | 65-71 | 7 | |
| α-helix | 78-84 | 7 | |
| α-helix | 91-98 | 8 | |
| β-strand | 103-116 | 14 | 94 |
| β-strand | 119-131 | 13 | 94 |
| β-strand | 136-144 | 9 | 94 |
| α-helix | 147-160 | 14 | |
| β-strand | 162-164 | 3 | 94 |
| β-strand | 168 | 1 | 95 |
| β-strand | 179 | 1 | 95 |
| β-strand | 184-188 | 5 | 96 |
| β-strand | 191-196 | 6 | 96 |
| β-strand | 204-205 | 2 | 96 |
| α-helix | 208-216 | 9 | |
| β-strand | 222-227 | 6 | 96 |
| α-helix | 233-245 | 13 | |
| α-helix | 253-255 | 3 | |
| α-helix | 258-259 | 2 | |
| α-helix | 265-268 | 4 | |
| α-helix | 270-275 | 6 | |
Chain AB: 2 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-9 | 3 | |
| β-strand | 10-21 | 12 | 11 |
| β-strand | 27-34 | 8 | 11 |
| β-strand | 41-47 | 7 | 11 |
| β-strand | 55-58 | 4 | 11 |
| α-helix | 65-67 | 3 | |
Chain Ac: 11 helices, 9 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-28 | 22 | |
| β-strand | 34-42 | 9 | 101 |
| β-strand | 45-52 | 8 | 101 |
| α-helix | 55-59 | 5 | |
| α-helix | 61-63 | 3 | |
| α-helix | 64-77 | 14 | |
| α-helix | 79-80 | 2 | |
| β-strand | 84-89 | 6 | 101 |
| α-helix | 98-111 | 14 | |
| α-helix | 115-128 | 14 | |
| β-strand | 133-141 | 9 | 102 |
| β-strand | 147-155 | 9 | 102 |
| α-helix | 163-167 | 5 | |
| β-strand | 168-176 | 9 | 102 |
| β-strand | 181-189 | 9 | 102 |
| α-helix | 190-192 | 3 | |
| α-helix | 203-204 | 2 | |
| β-strand | 209-210 | 2 | 103 |
| α-helix | 211-214 | 4 | |
| β-strand | 223-226 | 4 | 51 |
Chain AC: 5 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 81-84 | 4 | |
| α-helix | 88-93 | 6 | |
| α-helix | 101-105 | 5 | |
| β-strand | 106-108 | 3 | 17 |
| β-strand | 114-116 | 3 | 17 |
| α-helix | 119 | 1 | |
| β-strand | 120 | 1 | 18 |
| α-helix | 121 | 1 | |
| β-strand | 131 | 1 | 18 |
| β-strand | 133-134 | 2 | 19 |
| β-strand | 139-141 | 3 | 19 |
| β-strand | 146-148 | 3 | 19 |
Chain Ad: 10 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 9-10 | 2 | 105 |
| α-helix | 16-18 | 3 | |
| β-strand | 27-28 | 2 | 105 |
| α-helix | 30-32 | 3 | |
| α-helix | 38-40 | 3 | |
| β-strand | 42-43 | 2 | 106 |
| α-helix | 44-46 | 3 | |
| α-helix | 47-51 | 5 | |
| α-helix | 58-66 | 9 | |
| β-strand | 71-72 | 2 | 107 |
| β-strand | 75-76 | 2 | 107 |
| β-strand | 83-84 | 2 | 106 |
| β-strand | 89-92 | 4 | 107 |
| β-strand | 97-103 | 7 | 107 |
| β-strand | 109-114 | 6 | 107 |
| α-helix | 118-120 | 3 | |
| β-strand | 121-125 | 5 | 108 |
| β-strand | 126-132 | 7 | 109 |
| α-helix | 133-135 | 3 | |
| β-strand | 136-141 | 6 | 109 |
| β-strand | 146-148 | 3 | 109 |
| β-strand | 159-163 | 5 | 108 |
| β-strand | 168-173 | 6 | 108 |
| β-strand | 180-183 | 4 | 110 |
| β-strand | 192-199 | 8 | 110 |
| β-strand | 207-211 | 5 | 110 |
| β-strand | 217-221 | 5 | 110 |
| α-helix | 222-224 | 3 | |
| β-strand | 225-230 | 6 | 110 |
| β-strand | 233-234 | 2 | 110 |
| α-helix | 248-262 | 15 | |
Chain AD: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 85-89 | 5 | |
| α-helix | 91-92 | 2 | |
| α-helix | 94-97 | 4 | |
| α-helix | 99-102 | 4 | |
| α-helix | 104-115 | 12 | |
| α-helix | 126-128 | 3 | |
73 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 28S rRNA | B5 | RNA | 4808 | Oryctolagus cuniculus | |
| 5S rRNA | B7 | RNA | 120 | Oryctolagus cuniculus | |
| 5.8S rRNA | B8 | RNA | 158 | Oryctolagus cuniculus | |
| 60S ribosomal protein L8 | BA | protein | 257 | Oryctolagus cuniculus | F2X241 (AlphaFold model) |
| Ribosomal protein L3 | BB | protein | 403 | Oryctolagus cuniculus | G1TL06 (AlphaFold model) |
| 60S ribosomal protein L4 | BC | protein | 413 | Oryctolagus cuniculus | G1SVW5 (AlphaFold model) |
| Ribosomal protein L5 eukaryotic C-terminal domain-containing protein | BD | protein | 297 | Oryctolagus cuniculus | P19949 (AlphaFold model) |
| 60S ribosomal protein L6 | BE | protein | 291 | Oryctolagus cuniculus | G1SKF7 |
| Ribosomal Protein uL30 | BF | protein | 247 | Oryctolagus cuniculus | G1SV32 |
| 60S ribosomal protein L7a | BG | protein | 266 | Oryctolagus cuniculus | P62424 |
| 60S ribosomal protein L9 | BH | protein | 192 | Oryctolagus cuniculus | G1SWI6 |
| 60S ribosomal protein L10 | BI | protein | 214 | Oryctolagus cuniculus | B7NZQ2 |
76 more molecules are not listed.
Sequence of entity 1 (B5), FASTA
>8P2K_1 28S rRNA (chains B5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGUGGGGCGCGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGC
GUGGUCCGGCCGUGCCGGCGGUCUCGGCGGAUCUUUCCCGCUCCCCGUUCCUCCCGACCC
CUCCACCCGCUCCCCCUCCCCCGCCGGUCUUCUCCCUUCACGGGGGGUGGGUCGGCGGGU
GCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCGCCCCCCGGCCGGCG
ACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACGG
CUGGGAAGGCCCCGGCGGGGAAGGUGGCCCGGGGGGACGCCUCGCCGCCGUCGUCCGCGG
CGGCGGCGGGCGCGACCCCUCCCCGGGUGUUACAGCCCCGCCCCGGCAGCAGCAGCUCGC
CGAAUCCCGGGGCCGAGGGAGCGAGACCUGUGUCGCCGCGCUCUCCCCCCUCCCGGCGCU
CCCCCCCGCGGGGGUCCCCCGCGAGGGGGCUCCCCCCGCGGGGGCGCGCCGGUGUCGCCG
CCCUCGCGGGCGCGGCACGGGGGGGCCGGGCCGCCCCUCCCACGGCGCGACCGCUCUCCC
GGCCCCCGCCGCCGCCUCUUCGGGCGUGCGGCGGGGGUGGGGCGGACUGUCCCCAGUGCG
CCCCGGGCGUGUCACGCCGUCGGGCUCGGGGGAGAAGUCGGCCACGGCGCGUCGCGCGCC
UCCGCGUCCCCCCCUCGCCGUCUCCGGGCGGCGGGGGGGGGUUUCGGCGCGGUGUUCUCG
GCGCGCGCGCGCGAGCGAGCGCACGGGGUCGGCGGCGAUGUCGGCUACCCACCCGACCCG
UCUUGAAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCC
GCCGUGGCGCAAUGAAGGUGAAGGCCGGCGGCGGCUUCCCGCCGUCGUCGGCCGAGGUGG
GAUCCCGAGGCCCUUCCAGUCCGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGC
CGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGG
CAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGG
UCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUC
CGAAGUUUCCCUCAGGAUAGCUGGCGCUCUCGCAACCCCGCAGUUUUAUCCGGUAAAGCG
AAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUA
AGAAGCCCGGCUCGCUGGCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUU
UUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCC
GACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUG
GAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAA
AAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCUGGCAGUCGGCAGAGCGA
GAAAGAGAGUGGAGCGCGCCGCGGGACUCCCCCCGCGGGGGUCCCCGGCCACCCCCCCCC
CGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGC
GCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAAC
GAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUC
AGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGC
CCUCAGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGG
CGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCG
GGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAG
AGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGC
CCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGC
AGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCA
AGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGG
GCGCGAAGCGGGGCUGGGCGCGCGCCGCGGCUGGACGAGGCGCCGCCGCCCCCCCCACGC
CCGGGGCGCCCUCCCCCGGCCGGGUCCGCUCCCUCGCGCGCGCGUGCGCCGUGGCGCGCG
CCGCGCGCGCGGCCGAGCCCCGUCUCCCUCCCCCCCUCUCCCCUCCCGGGGCGGGGUGCG
GGGAGGGGCGGGCGGGGCCGUCGCUCGCCGCGCGUGCGCGUCGCUGCGCGUGCGCCGCGC
GGGGGGUCCGGCGGGCCUCCGGACGGGGGCUCCGGGCACCCGGGCACCCGGGGGGCCGGC
GGCGGCGGCGACUCUGGACGCGAGCCGGGCCCUUCCCGUGGAUCGCCCCAGCUGCGGCGG
GCGUCGCGGCCGCCCUCGGGGAGCCCGGCGGGCGCCGCGUGCGCGCGCGUGCGCGCCCGG
GGUCGGGGGGGUGCGAGGCAGGGGAGGCCCUCUCUCCUCCUCCCCCACCCCGGCGCCGCG
GCGCCGCGCGUGCGCGCGCGGUCUCCCCCCGCCGGGUCCGCCCCCGGGGCCGCGGUUCCG
CGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGG
AAUCCGACUGUUUAAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAU
GUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAA
CGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGAC
GCGCAUGAAXGGAUGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAG
CCAAGGGAACGGGCUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUA
GUCUGGCACGGUGAAGAGACAUGAGAGGUGUAGAAUAAGUGGGAGGCCCCCGGCGCCCUC
CCGCCCCCGCGAGGGGGCGGGGCGGGGUCCGCCGGCCUUGCGGGCCGCCGGUGAAAUACC
ACUACUCUUAUCGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUC
UCGCUUCUGGCGCCAAGCGCCGGGCCCCGUCGGUCCGCGCGGGCCGGCGGCGGCCGGGCG
CGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCGGUACACCUGUCAAA
CGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCUCCCGUGGAGCAGAA
GGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCGUGAAAGCGGGGCCU
CACGAUCCUUCUGAGCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAAAGUUACCACAGGGA
UAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUGAUCCUUCGAUGUCG
GCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGUUCACCCACUAAUAG
GGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAUGU
GUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUUCAGACAUUUGGUGU
AUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGGAUUAUGACUGAACG
CCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCGAAGGAGCCUCGGUU
GGCCUCGGAUAGCCGGUCCCCCGCCGUCCCCGCCGGCGGCCCGCGUCGUGCGUCCGCCUC
GGCGGCGUGCGGCGCGCCCCCCGCCGCGCGUCGGGACCGGGGUCCGGUGCGGAGAGCCCU
UCGUCCCGGGAAAUGGGGCGCGGCCGGAAAGGGGGCCGCCCUCUCGCCCGUCACGCACCG
CACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACGACCUGCUUCUGGGUCGGGGU
UUCGUACGUAGCAGAGCAGCUCCCUCGCUGCGAUCUAUUGAAAGUCAGCCCUCGACACAA
GGGUUUGU
Sequence of entity 2 (B7), FASTA
>8P2K_2 5S rRNA (chains B7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 3 (B8), FASTA
>8P2K_3 5.8S rRNA (chains B8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUUG
Sequence of entity 4 (BA), FASTA
>8P2K_4 60S ribosomal protein L8 (chains BA)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNXQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN
Sequence of entity 5 (BB), FASTA
>8P2K_5 Ribosomal protein L3 (chains BB)
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREV
DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
NWHKSKKKAFTKYCKKWQDDAGKRQLDKDFSSMKKYCQVIRVLAHTQMRLLPLRQKKAHL
MEIQVNGGTVAEKLDWARERLEQQVPVSQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
NNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
EKIDLKFIDTTSKFGHGRFQTVEEKKAFMGPLKKDRIAKEEGA
Sequence of entity 6 (BC), FASTA
>8P2K_6 60S ribosomal protein L4 (chains BC)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCVIYNEDNGIVKAFRNIPGITLLNVTKLNILKL
APGGHVGRFCIWTESAFRKLDDLYGTWRKAASLKSNYNLPMHKMLNTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVERAAAALAA
KSDPKEAPAKKKPVVGKKKKPVVGRKAAAAKKPAADKKAADKRAGPEDKKPAA
Sequence of entity 7 (BD), FASTA
>8P2K_7 Ribosomal protein L5 eukaryotic C-terminal domain-containing protein (chains BD)
MXFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDI
ICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYE
GQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRF
PGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMY
KKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES
Sequence of entity 8 (BE), FASTA
>8P2K_8 60S ribosomal protein L6 (chains BE)
MAGEKAPAAKPDATKKSPAKKADHARGKAKKKTLAEKKPKKGKPHCSRNPVLVRGIGRYS
RSAMYSRKALYKRKYAAPKSRIERKKKREKVLATVTKPVGGDKNGGTRVVKLRKMPRYYP
TEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLSSGLLLVTG
PLSLNRVPLRRTHQKFVIATSTKIDISGVKIPKHLTDAYFKKKKLRKPRHQEGEIFDTEK
EKYEITEQRKVDQKAVDSQILPKIKAVPQLQGYLRSVFALTNGVYPHKLVF
Sequence of entity 9 (BF), FASTA
>8P2K_9 Ribosomal Protein uL30 (chains BF)
MEGAEEKKKVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEY
RQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGT
FVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNTLIARSLGK
YNIICMEDLIHEIYTVGKHFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQIN
RLIRRMN
Sequence of entity 10 (BG), FASTA
>8P2K_10 60S ribosomal protein L7a (chains BG)
MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRY
IRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEK
KAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVP
YCILKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGN
VLGPKSVARIAKLEKAKAKELATKLG
Sequence of entity 11 (BH), FASTA
>8P2K_11 60S ribosomal protein L9 (chains BH)
MKTILSNQTVDIPENVDISLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRPGVACSVSQAQKDELVLEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE
Sequence of entity 12 (BI), FASTA
>8P2K_12 60S ribosomal protein L10 (chains BI)
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL
SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG
KPQGTVARVHIGQVIMSIRTKLQNKEHVVEALRRAKFKFPGRQKIHISKKWGFTKFNADE
FEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| N | Any 5'-monophosphate nucleotide | C5 H11 O7 P | 73 |
| SPD | Spermidine | C7 H19 N3 | 30 |
| SPM | Spermine | C10 H26 N4 | 3 |
| MG | Magnesium ion | Mg | 420 |
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 1 |
| AAC | Acetylamino-acetic acid | C4 H7 N O3 | 1 |
| ZN | Zinc ion | Zn | 8 |
Water and common crystallization additives (UNX) are not listed.
Primary citation
NAC controls cotranslational N-terminal methionine excision in eukaryotes. Gamerdinger, M., Jia, M., Schloemer, R. et al. Science (2023) 380:1238-1243. DOI 10.1126/science.adg3297 · PubMed
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