8VRJ: Tubulin alpha-1B chain
Rigid body fitted model for gamma tubulin ring complex capped microtubule. Determined by electron microscopy at 7.7 Å resolution. Released 27 Mar 2024.
- Method
- Electron microscopy
- Resolution
- 7.7 Å
- Organism
- Homo sapiens
- Chains
- 60
- Atoms
- 121,890
- Mol. weight
- 4136.87 kDa
- Released
- 27 Mar 2024
Explore 8VRJ in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8VRJ contains 1,360 α-helices and 751 β-strands across 60 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chains 1, O, P, Q, R, S, T, U, V, W, X, Y and Z: 27 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-9 | 8 | 1 |
| α-helix | 10-28 | 19 | |
| α-helix | 48-50 | 3 | |
| β-strand | 53-55 | 3 | 2 |
| β-strand | 61-63 | 3 | 2 |
| β-strand | 65-69 | 5 | 1 |
| α-helix | 72-80 | 9 | |
| α-helix | 89-91 | 3 | |
| β-strand | 92-94 | 3 | 1 |
| α-helix | 103-104 | 2 | |
| α-helix | 105-109 | 5 | |
| α-helix | 111-113 | 3 | |
| α-helix | 115-128 | 14 | |
| β-strand | 131-140 | 10 | 1 |
| α-helix | 144 | 1 | |
| α-helix | 145-149 | 5 | |
| α-helix | 150-160 | 11 | |
| β-strand | 165-171 | 7 | 1 |
| α-helix | 172-174 | 3 | |
| α-helix | 183-196 | 14 | |
| β-strand | 200-204 | 5 | 1 |
| α-helix | 206-216 | 11 | |
| α-helix | 224-243 | 20 | |
| β-strand | 248 | 1 | 1 |
| α-helix | 252-259 | 8 | |
| β-strand | 269 | 1 | 1 |
| β-strand | 271 | 1 | 3 |
| β-strand | 272 | 1 | 1 |
| α-helix | 278-283 | 6 | |
| α-helix | 288-296 | 9 | |
| α-helix | 298-300 | 3 | |
| β-strand | 301 | 1 | 3 |
| α-helix | 307-309 | 3 | |
| β-strand | 312-321 | 10 | 1 |
| α-helix | 325-337 | 13 | |
| β-strand | 343 | 1 | 1 |
| β-strand | 351-356 | 6 | 1 |
| α-helix | 359-363 | 5 | |
| α-helix | 369-370 | 2 | |
| β-strand | 373-381 | 9 | 1 |
| α-helix | 384-400 | 17 | |
| α-helix | 405-409 | 5 | |
| α-helix | 415-436 | 22 | |
| α-helix | 438-439 | 2 | |
Chains 2, o, p, q, r, s, t, u, v, w, x, y and z: 24 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 3-9 | 7 | 11 |
| α-helix | 10-28 | 19 | |
| β-strand | 30 | 1 | 12 |
| β-strand | 35 | 1 | 13 |
| β-strand | 36 | 1 | 12 |
| α-helix | 42-45 | 4 | |
| α-helix | 47-49 | 3 | |
| β-strand | 51-53 | 3 | 14 |
| β-strand | 58 | 1 | 13 |
| β-strand | 59-61 | 3 | 14 |
| β-strand | 63-67 | 5 | 11 |
| α-helix | 70-78 | 9 | |
| α-helix | 87-89 | 3 | |
| β-strand | 90-92 | 3 | 11 |
| α-helix | 101-102 | 2 | |
| α-helix | 103-107 | 5 | |
| α-helix | 109-126 | 18 | |
| β-strand | 130-138 | 9 | 11 |
| α-helix | 143-158 | 16 | |
| β-strand | 163-170 | 8 | 11 |
| α-helix | 171-172 | 2 | |
| α-helix | 181-195 | 15 | |
| β-strand | 198-203 | 6 | 11 |
| α-helix | 204-209 | 6 | |
| α-helix | 210-214 | 5 | |
| α-helix | 222-241 | 20 | |
| β-strand | 246 | 1 | 15 |
| α-helix | 250-257 | 8 | |
| β-strand | 265-266 | 2 | 11 |
| β-strand | 267 | 1 | 15 |
| β-strand | 270 | 1 | 15 |
| α-helix | 278-280 | 3 | |
| α-helix | 286-293 | 8 | |
| α-helix | 305-307 | 3 | |
| β-strand | 310-318 | 9 | 15 |
| α-helix | 323-336 | 14 | |
| α-helix | 338-340 | 3 | |
| β-strand | 341 | 1 | 15 |
| β-strand | 349-354 | 6 | 15 |
| α-helix | 357-358 | 2 | |
| β-strand | 364-371 | 8 | 15 |
| α-helix | 374-390 | 17 | |
| α-helix | 395-401 | 7 | |
| α-helix | 405-424 | 20 | |
Chain 3: 15 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 1485-1503 | 19 | |
| α-helix | 1505-1515 | 11 | |
| α-helix | 1524-1534 | 11 | |
| α-helix | 1550-1557 | 8 | |
| α-helix | 1558-1561 | 4 | |
| β-strand | 1573 | 1 | 23 |
| β-strand | 1597 | 1 | 23 |
| α-helix | 1602-1605 | 4 | |
| α-helix | 1615-1639 | 25 | |
| α-helix | 1641-1643 | 3 | |
| α-helix | 1653-1678 | 26 | |
| α-helix | 1679-1683 | 5 | |
| α-helix | 1684-1686 | 3 | |
| α-helix | 1699-1708 | 10 | |
| α-helix | 1723-1741 | 19 | |
| α-helix | 1762-1785 | 24 | |
| α-helix | 1793-1802 | 10 | |
Chain 5: 5 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-20 | 9 | |
| α-helix | 31-39 | 9 | |
| α-helix | 51-63 | 13 | |
| α-helix | 70-84 | 15 | |
| α-helix | 90-99 | 10 | |
Chain 6: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-14 | 8 | |
| α-helix | 17-18 | 2 | |
| α-helix | 33-50 | 18 | |
| α-helix | 68-79 | 12 | |
| α-helix | 83-95 | 13 | |
| α-helix | 108-114 | 7 | |
| α-helix | 161-182 | 22 | |
Chain 7: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 16-34 | 19 | |
| α-helix | 41-53 | 13 | |
| α-helix | 57-74 | 18 | |
Chain 8: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 20-33 | 14 | |
| α-helix | 41-53 | 13 | |
| α-helix | 57-74 | 18 | |
Chain 9: 25 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 8-11 | 4 | 59 |
| β-strand | 16-21 | 6 | 59 |
| β-strand | 29-32 | 4 | 59 |
| β-strand | 35-38 | 4 | 60 |
| β-strand | 53-54 | 2 | 60 |
| α-helix | 56-60 | 5 | |
| α-helix | 62-64 | 3 | |
| β-strand | 65-68 | 4 | 60 |
| α-helix | 79-88 | 10 | |
| α-helix | 89-94 | 6 | |
| α-helix | 98-100 | 3 | |
| β-strand | 103-107 | 5 | 59 |
| α-helix | 113-121 | 9 | |
| α-helix | 122-126 | 5 | |
| β-strand | 131-136 | 6 | 59 |
| α-helix | 137-144 | 8 | |
| β-strand | 150-151 | 2 | 61 |
| β-strand | 162 | 1 | 62 |
| β-strand | 164-166 | 3 | 61 |
| β-strand | 169-170 | 2 | 61 |
| α-helix | 172-174 | 3 | |
| β-strand | 176 | 1 | 62 |
| α-helix | 182-196 | 15 | |
| α-helix | 206-216 | 11 | |
| α-helix | 223-232 | 10 | |
| β-strand | 238-241 | 4 | 63 |
| β-strand | 247-250 | 4 | 63 |
| α-helix | 253-259 | 7 | |
| α-helix | 264-267 | 4 | |
| α-helix | 274-277 | 4 | |
| α-helix | 282-284 | 3 | |
| α-helix | 287-289 | 3 | |
| α-helix | 290-294 | 5 | |
| β-strand | 297-298 | 2 | 61 |
| α-helix | 302-304 | 3 | |
| α-helix | 309-320 | 12 | |
| β-strand | 329-330 | 2 | 61 |
| α-helix | 335-337 | 3 | |
| α-helix | 338-347 | 10 | |
| α-helix | 350-355 | 6 | |
| β-strand | 357-358 | 2 | 59 |
| α-helix | 359-365 | 7 | |
| α-helix | 369-373 | 5 | |
7 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Tubulin alpha-1B chain | 1, O, P, Q, R, S, T, U, V, W, X, Y, Z | protein | 457 | Homo sapiens | P68363 (AlphaFold model) |
| Tubulin beta-3 chain | 2, o, p, q, r, s, t, u, v, w, x, y, z | protein | 456 | Homo sapiens | Q13509 (AlphaFold model) |
| TUBGCP6 protein | 3, 6, L | protein | 1811 | Homo sapiens | Q96RT7 (AlphaFold model) |
| Gamma-tubulin complex component 3 | 5, B, D, F, H, N | protein | 907 | Homo sapiens | Q96CW5 (AlphaFold model) |
| Mitotic-spindle organizing protein 1 | 7, 8 | protein | 82 | Homo sapiens | Q08AG7 |
| Actin, cytoplasmic 1 | 9 | protein | 375 | Homo sapiens | P60709 |
| Isoform 3 of Gamma-tubulin complex component 2 | A, C, E, G, M | protein | 930 | Homo sapiens | Q9BSJ2 |
| Isoform 2 of Gamma-tubulin complex component 4 | I, K | protein | 666 | Homo sapiens | Q9UGJ1 |
| Gamma-tubulin complex component 5 | J | protein | 1024 | Homo sapiens | Q96RT8 |
| Tubulin gamma-1 chain | a, b, c, d, e, f, g, h, i, j, k, l, m, n | protein | 457 | Homo sapiens | P23258 |
Sequence of entity 1 (1, O, P, Q, R, S, T, U, V, W, X, Y, Z), FASTA
>8VRJ_1 Tubulin alpha-1B chain (chains 1, O, P, Q, R, S, T, U, V, W, X, Y, Z)
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIHHHHHHGGGDDSFNTFFS
ETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEI
IDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPA
PQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQI
VSSITASLRFDGALNVDLTDFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNA
CFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVG
INYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGME
EGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
Sequence of entity 2 (2, o, p, q, r, s, t, u, v, w, x, y, z), FASTA
>8VRJ_2 Tubulin beta-3 chain (chains 2, o, p, q, r, s, t, u, v, w, x, y, z)
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV
PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV
EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM
AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG
LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATAEEEGEMYEDDEEESEAQGPKENLYFQ
Sequence of entity 3 (3, 6, L), FASTA
>8VRJ_3 TUBGCP6 protein (chains 3, 6, L)
MASITQLFDDLCEALLPAAKTHLGQRSVNRKRAKRSLKKVAYNALFTNLFQDETQQLQPD
MSKLPARNKILMLSFDLRVGGLGPKADRLEELVEELEAAPCCPLLEVGSVLDLLVQLAGS
GPPQVLPRKRDYFLNNKHVGRNVPYSGYDCDDLSVFEMDVQSLISREECLCHSMIQETLQ
VMEAAPGTGLPTVGLFSFGDPCGDRFERDTRVSLFGALVHSRTYDMDVRLGLPPVPDNAD
LSGLAIKVPPSVDQWEDEGFQSASNLTPDSQSEPSVTPDVDLWEAALTYEASKRRCWERV
GCPPGHREEPYLTEAGRDAFDKFCRLHQGELQLLAGGVLQAPQPVLVKECELVKDVLNVL
IGVVSATFSLCQPAQAFVVKRGVHVSGASPESISSLLSEVAEYGTCYTRLSHFSLQPVLD
SLYSKGLVFQAFTSGLRRYLQYYRACVLSTPPTLSLLTIGFLFKKLGRQLRYLAELCGVG
AVLPGTCGGGPRAAFPTGVKLLSYLYQEALHNCSNEHYPVLLSLLKTSCEPYTRFIHDWV
YSGVFRDAYGEFMIQVNHEYLSFRDKLYWTHGYVLISKEVEDCVPVFLKHIAHDIYVCGK
TINLLKLCCPRHYLCWSDVPVPRISVIFSLEELKEIEKDCAVYVGRMERVARHSSVSKEE
KELRMEIAKQELIAHAREAASRVLSALSDRQMSERMALDARKREQFQRLKEQFVKDQERR
QAARQEELDDDFSYARELRDRERRLKSLEEELERKASKLSAEAARREQKALWRIQRHRLE
SARLRFLLEDEKHIQEMLKAVSEAHQPQEPPDVLLSVHPQVTSPGPEHPEGGQGCDSGSA
EQHSPAWDGWNRPGLLTPQPLKPLAVGAGGRGLQQAEGARPFSDSLSIGDFLPVGPGAEP
SVQTGMVPLLEVALQTINLDLPPSAPGEAPAAASTQPSRPQEYDFSTVLRPAVATSPAPG
PLQAAECSLGSSGLQLWEDSCGKMDACGSASRETLLPSHPPRRAALEEGSSQPTERLFGQ
VSGGGLPTGDYASEIAPTRPRWNTHGHVSDASIRVGENVSDVAPTQPRWNTHGHVSNASI
SLGESVSDVAPTRPRWNIHGHVSNASIRVGENVSDVAPTRPRWNTHGHVSNASIRVGENV
SDVAPTRPRWNTHGHVSDASISLGESVSDMAPARPRWNTHGHVSDASISLGESVSDMAPT
RPRWNTHGHVSDTSIRVGENVSDVAPIRSRCNTHGHVSDASISLGEPVSDVVSTRPRWNT
HVPIPPPHMVLGALSPEAEPNTPRPQQSPPGHTSQSALSLGAQSAVLDCGPRLPVEVGPS
LSSPSSGCGEGSISVGENVSDVAPTQPWWPNTPGDSVSEELGPGRSGDTEDLSPNWPLNS
QEDTAAQSSPGRGEEAEASAAEAQGGEQAYLAGLAGQYHLERYPDSYESMSEPPIAHLLR
PVLPRAFAFPVDPQVQSAADETAVQLSELLTLPVLMKRSITAPLAAHISLVNKAAVDYFF
VELHLEAHYEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSVLSKALQC
SLHGDTPHASNLSLALKYLPEVFAPNAPDVLSCLELRYKVDWPLNIVITEGCLSKYSGVF
SFLLQLKLMMWALKDVCFHLKRTALLSHMAGSVQFRQLQLFKHEMQHFVKVIQGYIANQI
LHVTWCEFRARLATVGDLEEIQRAHAEYLHEAVFRGLLTEKAAPVMNVIHSIFSLVLKFR
SQLISQAWGPPGGPRGAEHPNFALMQQSYNTFKYYSHFLFKVVTKLVNRGYQPHLEDFLL
RINFNNYYQDA
Sequence of entity 4 (5, B, D, F, H, N), FASTA
>8VRJ_4 Gamma-tubulin complex component 3 (chains 5, B, D, F, H, N)
MATPDQKSPNVLLQNLCCRILGRSEADVAQQFQYAVRVIGSNFAPTVERDEFLVAEKIKK
ELIRQRREADAALFSELHRKLHSQGVLKNKWSILYLLLSLSEDPRRQPSKVSSYATLFAQ
ALPRDAHSTPYYYARPQTLPLSYQDRSAQSAQSSGSVGSSGISSIGLCALSGPAPAPQSL
LPGQSNQAPGVGDCLRQQLGSRLAWTLTANQPSSQATTSKGVPSAVSRNMTRSRREGDTG
GTMEITEAALVRDILYVFQGIDGKNIKMNNTENCYKVEGKANLSRSLRDTAVRLSELGWL
HNKIRRYTDQRSLDRSFGLVGQSFCAALHQELREYYRLLSVLHSQLQLEDDQGVNLGLES
SLTLRRLLVWTYDPKIRLKTLAALVDHCQGRKGGELASAVHAYTKTGDPYMRSLVQHILS
LVSHPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFMTMDQS
RKVLLIGKSINFLHQVCHDQTPTTKMIAVTKSAESPQDAADLFTDLENAFQGKIDAAYFE
TSKYLLDVLNKKYSLLDHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTGI
LETAVRATNAQFDSPEILRRLDVRLLEVSPGDTGWDVFSLDYHVDGPIATVFTRECMSHY
LRVFNFLWRAKRMEYILTDIRKGHMCNAKLLRNMPEFSGVLHQCHILASEMVHFIHQMQY
YITFEVLECSWDELWNKVQQAQDLDHIIAAHEVFLDTIISRCLLDSDSRALLNQLRAVFD
QIIELQNAQDAIYRAALEELQRRLQFEEKKKQREIEGQWGVTAAEEEEENKRIGEFKESI
PKMCSQLRILTHFYQGIVQQFLVLLTTSSDESLRFLSFRLDFNEHYKAREPRLRVSLGTR
GRRSSHT
Sequence of entity 5 (7, 8), FASTA
>8VRJ_5 Mitotic-spindle organizing protein 1 (chains 7, 8)
MASSSGAGAAAAAAAANLNAVRETMDVLLEISRILNTGLDMETLSICVRLCEQGINPEAL
SSVIKELRKATEALKAAENMTS
Sequence of entity 6 (9), FASTA
>8VRJ_6 Actin, cytoplasmic 1 (chains 9)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF
Sequence of entity 7 (A, C, E, G, M), FASTA
>8VRJ_7 Isoform 3 of Gamma-tubulin complex component 2 (chains A, C, E, G, M)
MSEFRIHHDVNELLSLLRVHGGDGAEVYIDLLQKNRTPYVTTTVSAHSAKVKIAEFSRTP
EDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQYLQQNAKERAELAAAAVGSSTTSI
NVPAAASKISMQELEELRKQLGSVATGSTLQQSLELKRKMLRDKQNKKNSGQHLPIFPAW
VYERPALIGDFLIGAGISTDTALPIVLLGWSLALSPRLKCSGVISAHCGLHLPGTLPLAS
QESAVVEDLLYVLVGVDGRYVSAQPLAGRQSRTFLVDPNLDLSIRELVHRILPVAASYSA
VTRFIEEKSSFEYGQVNHALAAAMRTLVKEHLILVSQLEQLHRQGLLSLQKLWFYIQPAM
RTMDILASLATSVDKGECLGGSTLSLLHDRSFSYTGDSQAQELCLYLTKAASAPYFEVLE
KWIYRGIIHDPYSEFMVEEHELRKERIQEDYNDKYWDQRYTIVQQQIPSFLQKMADKILS
TGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKELVAH
LRSIKRYFLMDQGDFFVHFMDLAEEELRKPVEDITPPRLEALLELALRMSTANTDPFKDD
LKIDLMPHDLITQLLRVLAIETKQEKAMAHADPTELALSGLEAFSFDYIVKWPLSLIINR
KALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHSLHSAQWFAGAFTLRQRMLNFVQN
IQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTGFLDTCLKDCMLTNPELLKVFSKLM
SVCVMFTNCMQKFTQSMKLDGELGGQTLEHSTVLGLPAGAEERARKELARKHLAEHADTV
QLVSGFEATINKFDKNFSAHLLDLLARLSIYSTSDCEHGMASVISRLDFNGFYTERLERL
SAERSQKATPQVPVLRGPPAPAPRVAVTAQ
Sequence of entity 8 (I, K), FASTA
>8VRJ_8 Isoform 2 of Gamma-tubulin complex component 4 (chains I, K)
MIHELLLALSGYPGSIFTWNKRSGLQVSQDFPFLHPSETSVLNRLCRLGTDYIRFTEFIE
QYTGHVQQQDHHPSQQGQGGLHGIYLRAFCTGLDSVLQPYRQALLDLEQEFLGDPHLSIS
HVNYFLDQFQLLFPSVMVVVEQIKSQKIHGCQILETVYKHSCGGLPPVRSALEKILAVCH
GVMYKQLSAWMLHGLLLDQHEEFFIKQGPSSGNVSAQPEEDEEDLGIGGLTGKQLRELQD
LRLIEEENMLAPSLKQFSLRVEILPSYIPVRVAEKILFVGESVQMFENQNVNLTRKGSIL
KNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKLMVEESDLLGQLKIIKDF
YLLGRGELFQAFIDTAQHMLKTPPTAVTEHDVNVAFQQSAHKVLLDDDNLLPLLHLTIEY
HGKEHKDATQAREGPSRETSPREAPASGWAALGLSYKVQWPLHILFTPAVLEKYNVVFKY
LLSVRRVQAELQHCWALQMQRKHLKSNQTDAIKWRLRNHMAFLVDNLQYYLQVDVLESQF
SQLLHQINSTRDFESIRLAHDHFLSNLLAQSFILLKPVFHCLNEILDLCHSFCSLVSQNL
GPLDERGAAQLSILVKGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGT
LGSFGM
Sequence of entity 9 (J), FASTA
>8VRJ_9 Gamma-tubulin complex component 5 (chains J)
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHK
IEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDS
PSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSRE
DSGIQVDRTPLEEQDQNGKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHS
NLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNI
IVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRT
YQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGV
AEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWI
VHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQG
PSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESV
QSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDF
HEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYL
QAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSIS
FENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDV
LLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNY
IMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAG
MEQS
Sequence of entity 10 (a, b, c, d, e, f, g, h, i, j, k, l, m, n), FASTA
>8VRJ_10 Tubulin gamma-1 chain (chains a, b, c, d, e, f, g, h, i, j, k, l, m, n)
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY
IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFD
IIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD
VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSAST
TTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP
KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVAL
SRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE
MDTSREIVQQLIDEYHAATRPDYISWGTQEQENLYFQ
Primary citation
Structure of the gamma-tubulin ring complex-capped microtubule. Aher, A., Urnavicius, L., Xue, A. et al. Nat Struct Mol Biol (2024) 31:1124-1133. DOI 10.1038/s41594-024-01264-z · PubMed
Other PDB entries of the same protein (UniProt P68363 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 6S8L 1.8 Å, Structure, Thermodynamics, and Kinetics of Plinabulin Binding to two Tubulin Isotypes
- 6J8O 1.85 Å, Structure of a hypothetical protease
- 7PJF 1.86 Å, Inhibiting parasite proliferation using a rationally designed anti-tubulin agent
- 6J4V 2.1 Å, Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and…
- 8VT7 2.66 Å, Structure of the gamma tubulin ring complex nucleated microtubule protofilament.
- 7Z6S 2.9 Å, MATCAP bound to a human 14 protofilament microtubule
- 8V2J 2.9 Å, Structure of alpha1B and betaI/IVb microtubule bound to GDP
- 9COC 2.9 Å, Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GDP
- 9BP6 3.1 Å, Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
- 9CMM 3.1 Å, Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
- 7LXB 3.26 Å, HeLa-tubulin in complex with cryptophycin 52
- 9HQ4 3.28 Å, TTLL11 bound to microtubule
Browse structure collections
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