8XU8: State 2c(S2c) of yeast 80S ribosome
State 2c(S2c) of yeast 80S ribosome bound to compact eEF2 and 2 tRNAs during peptidyl transferation. Determined by electron microscopy at 3.4 Å resolution. Released 11 Dec 2024.
- Method
- Electron microscopy
- Resolution
- 3.4 Å
- Organism
- Saccharomyces cerevisiae S288C
- Chains
- 81
- Atoms
- 209,284
- Mol. weight
- 3168.3 kDa
- Released
- 11 Dec 2024
Explore 8XU8 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8XU8 contains 534 α-helices and 549 β-strands across 75 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 6 helices, 9 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-20 | 9 | |
| α-helix | 24-30 | 7 | |
| β-strand | 32-34 | 3 | 7 |
| β-strand | 35 | 1 | 8 |
| α-helix | 36 | 1 | |
| α-helix | 37-43 | 7 | |
| β-strand | 47-49 | 3 | 7 |
| β-strand | 55-58 | 4 | 8 |
| β-strand | 67-68 | 2 | 8 |
| β-strand | 70-74 | 5 | 9 |
| β-strand | 79-88 | 10 | 9 |
| β-strand | 94-99 | 6 | 9 |
| α-helix | 101-103 | 3 | |
| β-strand | 104-108 | 5 | 8 |
| α-helix | 113-122 | 10 | |
Chain b: 6 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 9-13 | 5 | 15 |
| β-strand | 22-29 | 8 | 15 |
| β-strand | 40-48 | 9 | 15 |
| α-helix | 49-52 | 4 | |
| α-helix | 60-66 | 7 | |
| β-strand | 69-76 | 8 | 15 |
| β-strand | 80-86 | 7 | 15 |
| α-helix | 91-95 | 5 | |
| α-helix | 104-123 | 20 | |
| α-helix | 128-131 | 4 | |
| α-helix | 133-135 | 3 | |
Chain c: 6 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-11 | 5 | |
| α-helix | 42-48 | 7 | |
| β-strand | 72-73 | 2 | 21 |
| α-helix | 75-78 | 4 | |
| α-helix | 84-92 | 9 | |
| β-strand | 99-100 | 2 | 98 |
| β-strand | 101-103 | 3 | 22 |
| α-helix | 104-107 | 4 | |
| β-strand | 111-112 | 2 | 21 |
| β-strand | 124-127 | 4 | 22 |
| β-strand | 129-130 | 2 | 21 |
| α-helix | 132-141 | 10 | |
| β-strand | 145-147 | 3 | 22 |
Chain d: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-18 | 7 | |
| α-helix | 22-26 | 5 | |
| α-helix | 37-57 | 21 | |
Chain D: 9 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 6-9 | 4 | |
| β-strand | 28 | 1 | 25 |
| α-helix | 29-32 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 25 |
| α-helix | 50-51 | 2 | |
| α-helix | 57 | 1 | |
| β-strand | 58-64 | 7 | 25 |
| β-strand | 71-77 | 7 | 25 |
| β-strand | 79 | 1 | 26 |
| β-strand | 83 | 1 | 27 |
| β-strand | 87-91 | 5 | 25 |
| β-strand | 101-103 | 3 | 25 |
| β-strand | 112-114 | 3 | 25 |
| β-strand | 116 | 1 | 28 |
| β-strand | 126 | 1 | 28 |
| β-strand | 134-140 | 7 | 25 |
| β-strand | 145-149 | 5 | 25 |
| β-strand | 155-159 | 5 | 25 |
| β-strand | 163-166 | 4 | 25 |
| β-strand | 169 | 1 | 26 |
| α-helix | 182-190 | 9 | |
| β-strand | 225 | 1 | 29 |
| α-helix | 229-230 | 2 | |
| β-strand | 238 | 1 | 29 |
| α-helix | 245-247 | 3 | |
Chain e: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-20 | 11 | |
| β-strand | 23 | 1 | 36 |
| α-helix | 28-36 | 9 | |
| β-strand | 41-44 | 4 | 36 |
| α-helix | 50-63 | 14 | |
| β-strand | 66-69 | 4 | 36 |
| α-helix | 74-81 | 8 | |
| β-strand | 89-92 | 4 | 36 |
Chain E: 15 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-10 | 2 | |
| α-helix | 27-28 | 2 | |
| α-helix | 33-35 | 3 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 31 |
| β-strand | 45-59 | 15 | 32 |
| β-strand | 71-80 | 10 | 32 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 33 |
| β-strand | 98-105 | 8 | 33 |
| α-helix | 112-118 | 7 | |
| α-helix | 131-139 | 9 | |
| α-helix | 142-153 | 12 | |
| β-strand | 157-164 | 8 | 33 |
| β-strand | 179-182 | 4 | 33 |
| β-strand | 183-184 | 2 | 31 |
| α-helix | 188-197 | 10 | |
| β-strand | 201-203 | 3 | 33 |
| α-helix | 205-208 | 4 | |
| β-strand | 214-220 | 7 | 32 |
| α-helix | 221-222 | 2 | |
| β-strand | 223-227 | 5 | 34 |
| α-helix | 229-232 | 4 | |
| α-helix | 235-239 | 5 | |
| β-strand | 268-271 | 4 | 34 |
| β-strand | 274-285 | 12 | 32 |
| α-helix | 307 | 1 | |
| β-strand | 311 | 1 | 35 |
| β-strand | 315 | 1 | 35 |
| β-strand | 321-325 | 5 | 32 |
| β-strand | 335-340 | 6 | 32 |
| α-helix | 375-379 | 5 | |
Chain f: 5 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 8-15 | 8 | 41 |
| α-helix | 16-19 | 4 | |
| α-helix | 25-27 | 3 | |
| α-helix | 28-44 | 17 | |
| β-strand | 49-50 | 2 | 41 |
| α-helix | 53-60 | 8 | |
| β-strand | 70-79 | 10 | 41 |
| β-strand | 89-95 | 7 | 41 |
| β-strand | 107-109 | 3 | 41 |
| α-helix | 110 | 1 | |
67 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 18S rRNA | 2 | RNA | 1799 | Saccharomyces cerevisiae S288C | |
| 25S rRNA | A | RNA | 3394 | Saccharomyces cerevisiae S288C | |
| 5S rRNA | B | RNA | 121 | Saccharomyces cerevisiae S288C | |
| 5.8S rRNA | C | RNA | 158 | Saccharomyces cerevisiae S288C | |
| Large ribosomal subunit protein uL2A | D | protein | 251 | Saccharomyces cerevisiae S288C | P0CX45 (AlphaFold model) |
| Large ribosomal subunit protein uL3 | E | protein | 386 | Saccharomyces cerevisiae S288C | P14126 (AlphaFold model) |
| Large ribosomal subunit protein uL4A | F | protein | 361 | Saccharomyces cerevisiae S288C | P10664 (AlphaFold model) |
| Large ribosomal subunit protein uL18 | G | protein | 294 | Saccharomyces cerevisiae S288C | P26321 (AlphaFold model) |
| Large ribosomal subunit protein eL6B | H | protein | 175 | Saccharomyces cerevisiae S288C | P05739 |
| Large ribosomal subunit protein uL30A | I | protein | 222 | Saccharomyces cerevisiae S288C | P05737 |
| Large ribosomal subunit protein eL8A | J | protein | 233 | Saccharomyces cerevisiae S288C | P17076 |
| Large ribosomal subunit protein uL6A | K | protein | 191 | Saccharomyces cerevisiae S288C | P05738 |
68 more molecules are not listed.
Sequence of entity 1 (2), FASTA
>8XU8_1 18S rRNA (chains 2)
UAUCUGGUUGAUCCUGCCAGUAGUCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCU
AAGUAUAAGCAAUUUAUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUCGUUUAU
UUGAUAGUUCCUUUACUACAUGGUAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCUUAA
AAUCUCGACCCUUUGGAAGAGAUGUAUUUAUUAGAUAAAAAAUCAAUGUCUUCGGACUCU
UUGAUGAUUCAUAAUAACUUUUCGAAUCGCAUGGCCUUGUGCUGGCGAUGGUUCAUUCAA
AUUUCUGCCCUAUCAACUUUCGAUGGUAGGAUAGUGGCCUACCAUGGUUUCAACGGGUAA
CGGGGAAUAAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACAUCCAAGGA
AGGCAGCAGGCGCGCAAAUUACCCAAUCCUAAUUCAGGGAGGUAGUGACAAUAAAUAACG
AUACAGGGCCCAUUCGGGUCUUGUAAUUGGAAUGAGUACAAUGUAAAUACCUUAACGAGG
AACAAUUGGAGGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCAAUAGCGUAU
AUUAAAGUUGUUGCAGUUAAAAAGCUCGUAGUUGAACUUUGGGCCCGGUUGGCCGGUCCG
AUUUUUUCGUGUACUGGAUUUCCAACGGGGCCUUUCCUUCUGGCUAACCUUGAGUCCUUG
UGGCUCUUGGCGAACCAGGACUUUUACUUUGAAAAAAUUAGAGUGUUCAAAGCAGGCGUA
UUGCUCGAAUAUAUUAGCAUGGAAUAAUAGAAUAGGACGUUUGGUUCUAUUUUGUUGGUU
UCUAGGACCAUCGUAAUGAUUAAUAGGGACGGUCGGGGGCAUCAGUAUUCAAUUGUCAGA
GGUGAAAUUCUUGGAUUUAUUGAAGACUAACUACUGCGAAAGCAUUUGCCAAGGACGUUU
UCAUUAAUCAAGAACGAAAGUUAGGGGAUCGAAGAUGAUCAGAUACCGUCGUAGUCUUAA
CCAUAAACUAUGCCGACUAGGGAUCGGGUGGUGUUUUUUUAAUGACCCACUCGGCACCUU
ACGAGAAAUCAAAGUCUUUGGGUUCUGGGGGGAGUAUGGUCGCAAGGCUGAAACUUAAAG
GAAUUGACGGAAGGGCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACUCAACACGGG
GAAACUCACCAGGUCCAGACACAAUAAGGAUUGACAGAUUGAGAGCUCUUUCUUGAUUUU
GUGGGUGGUGGUGCAUGGCCGUUCUUAGUUGGUGGAGUGAUUUGUCUGCUUAAUUGCGAU
AACGAACGAGACCUUAACCUACUAAAUAGUGGUGCUAGCAUUUGCUGGUUAUCCACUUCU
UAGAGGGACUAUCGGUUUCAAGCCGAUGGAAGUUUGAGGCAAUAACAGGUCUGUGAUGCC
CUUAGACGUUCUGGGCCGCACGCGCGCUACACUGACGGAGCCAGCGAGUCUAACCUUGGC
CGAGAGGUCUUGGUAAUCUUGUGAAACUCCGUCGUGCUGGGGAUAGAGCAUUGUAAUUAU
UGCUCUUCAACGAGGAAUUCCUAGUAAGCGCAAGUCAUCAGCUUGCGUUGAUUACGUCCC
UGCCCUUUGUACACACCGCCCGUCGCUAGUACCGAUUGAAUGGCUUAGUGAGGCCUCAGG
AUCUGCUUAGAGAAGGGGGCAACUCCAUCUCAGAGCGGAGAAUUUGGACAAACUUGGUCA
UUUAGAGGAACUAAAAGUCGUAACAAGGUUUCCGUAGGUGAACCUGCGGAAGGAUCAUU
Sequence of entity 2 (A), FASTA
>8XU8_2 25S rRNA (chains A)
UUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGAAA
AGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUGAA
AUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCCUU
GUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGUGC
GGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGGGU
GGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUGAU
GGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGGGA
AGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUCUC
GCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCUUG
CCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACGUA
AGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGAGU
CUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUAGG
UUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGAGU
AAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCCAG
AGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUGGG
UAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCUCA
GGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGGGU
CGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAAUU
GAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCG
AUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCACA
AAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGG
AGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGU
GUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGGAG
GUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUGGU
GGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACGUC
AACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAGGC
CUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAUAU
GGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAGUU
AUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUUAU
GGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAAUC
CACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAGGU
GAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGUAA
CUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGCGG
GCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCUUG
UUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAACU
UAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUGGU
CAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGA
AAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAU
GCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCUAU
CUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAGAA
GACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAUAA
GUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAAUG
AAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGAUC
CGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGAUA
ACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGGUA
AAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUCGA
UCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAACU
GGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCUCU
UCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGAAC
GUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUACC
GCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGCGG
CUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUCUA
AGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUACG
AAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGCGG
AAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAUUU
GUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUACGA
UCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU
Sequence of entity 3 (B), FASTA
>8XU8_3 5S rRNA (chains B)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U
Sequence of entity 4 (C), FASTA
>8XU8_4 5.8S rRNA (chains C)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU
Sequence of entity 5 (D), FASTA
>8XU8_5 Large ribosomal subunit protein uL2A (chains D)
GRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKV
VFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPG
DRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLK
AGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAAR
RTGLLRGSQKT
Sequence of entity 6 (E), FASTA
>8XU8_6 Large ribosomal subunit protein uL3 (chains E)
SHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDLD
RPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYKN
WYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAEI
QLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPRK
THRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDRT
KKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWIDT
ASKFGKGRFQTPAEKHAFMGTLKKDL
Sequence of entity 7 (F), FASTA
>8XU8_7 Large ribosomal subunit protein uL4A (chains F)
SRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTS
AESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYA
TASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKV
LKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPG
AHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRP
AGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLKH
D
Sequence of entity 8 (G), FASTA
>8XU8_8 Large ribosomal subunit protein uL18 (chains G)
QKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDIICQ
IISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYKGVE
EVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRFPGW
DFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYTSA
HEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ
Sequence of entity 9 (H), FASTA
>8XU8_9 Large ribosomal subunit protein eL6B (chains H)
TAQQAPKWYPSEDVAAPKKTRKAVRPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLEDN
TLLVTGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEANL
FPEQQTKEIKTERVEDQKVVDKALLAEIKKTPLLKQYLSASFSLKNGDKPHLLKF
Sequence of entity 10 (I), FASTA
>8XU8_10 Large ribosomal subunit protein uL30A (chains I)
AEQVAAERAARKAANKEKRAIILERNAAYQKEYETAERNIIQAKRDAKAAGSYYVEAQHK
LVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVTKATLELLKLIEPYVAYGYPSYS
TIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILSIDDLIHEIITVGPHFKQANNFL
WPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLVKSMN
Sequence of entity 11 (J), FASTA
>8XU8_11 Large ribosomal subunit protein eL8A (chains J)
NPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLD
RNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGKSKQDASPKPYAVKYGLNHVVALI
ENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIVKGKARLGTLVNQKTSAVAALTEV
RAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKNSDSA
Sequence of entity 12 (K), FASTA
>8XU8_12 Large ribosomal subunit protein uL6A (chains K)
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNG
GRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGD
KKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIY
VSHKGFITEDL
Primary citation
Capturing eukaryotic ribosome dynamics in situ at high resolution. Cheng, J., Wu, C., Li, J. et al. Nat Struct Mol Biol (2025) 32:698-708. DOI 10.1038/s41594-024-01454-9 · PubMed
Other PDB entries of the same protein (UniProt P0CX45 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9PN5 1.75 Å, Composite map of hypomethylated 80S ribosome treated with hygromycin B
- 8CCS 1.97 Å, 80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
- 8CDR 2.04 Å, Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8CEH 2.05 Å, Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2…
- 8P8N 2.15 Å, Mouse RPL39 integrated into the yeast 60S ribosomal subunit
- 8PFR 2.15 Å, Mouse RPL39L integrated into the yeast 60S ribosomal subunit
- 8EVT 2.2 Å, Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome…
- 8T2Y 2.2 Å, Hypomethylated yeast 80S bound with cycloheximide, P-site tRNA, and A-site tRNA,…
- 8P8U 2.23 Å, Yeast 60S ribosomal subunit
- 8CGN 2.28 Å, Non-rotated 80S S. cerevisiae ribosome with ligands
- 8ZHC 2.3 Å, pre-frameshift complex of yeast 80S ribosome with eRF1 and mRNA of WNV
- 7UOO 2.34 Å, Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state
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