9BDE: Middle Region of Apolipoprotein B 100

Middle Region of Apolipoprotein B 100 bound to Low Density Lipoprotein Receptor. Determined by electron microscopy at 4.18 Å resolution. Released 25 Dec 2024.

Method: Electron microscopy
Resolution: 4.18 Å
Organisms: Mus musculus, Homo sapiens, Escherichia coli
Chains: 6
Atoms: 17,216
Mol. weight: 735.94 kDa
Ligands: NAG, CA
Released: 25 Dec 2024

Explore 9BDE in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9BDE contains 57 α-helices and 184 β-strands across 6 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 15 helices, 103 β-strands

Element	Residues	Length	Sheet
β-strand	1837-1843	7	7
α-helix	1845-1847	3
β-strand	1848-1856	9	7
α-helix	1859-1861	3
β-strand	1863-1873	11	7
β-strand	1878-1886	9	7
β-strand	1890-1899	10	7
β-strand	1906-1918	13	7
β-strand	1922-1934	13	7
β-strand	1940-1941	2	8
β-strand	1944-1952	9	7
β-strand	1962-1967	6	7
β-strand	1971-1972	2	8
β-strand	1982-1987	6	7
β-strand	1991	1	7
β-strand	2004-2005	2	9
β-strand	2009-2015	7	10
α-helix	2043-2047	5
β-strand	2050-2057	8	10
β-strand	2060-2061	2	9
α-helix	2075-2082	8
α-helix	2085-2093	9
α-helix	2387-2391	5
α-helix	2394-2405	12
α-helix	2409-2418	10
α-helix	2421-2427	7
α-helix	2433-2437	5
α-helix	2440-2467	28
α-helix	2738-2740	3
α-helix	2742-2744	3
α-helix	2753-2755	3
β-strand	2757	1	9
β-strand	2758-2760	3	11
β-strand	2761-2765	5	10
β-strand	2769-2770	2	10
β-strand	2773-2777	5	11
β-strand	2789-2796	8	11
β-strand	2798-2799	2	10
α-helix	2802-2804	3
β-strand	2807-2814	8	11
β-strand	2822-2826	5	11
β-strand	2828-2831	4	11
β-strand	2835-2845	11	11
β-strand	2850-2861	12	11
β-strand	2866-2868	3	11
β-strand	2871-2877	7	11
β-strand	2881-2883	3	11
β-strand	2889-2895	7	11
β-strand	2900-2906	7	11
β-strand	2908	1	11
β-strand	2912-2915	4	11
β-strand	2918-2920	3	11
β-strand	2923-2932	10	11
β-strand	2939-2951	13	11
β-strand	2954-2964	11	11
β-strand	2969	1	11
β-strand	2972-2978	7	11
β-strand	2984-2992	9	11
β-strand	3000-3008	9	11
β-strand	3016-3026	11	11
β-strand	3030-3040	11	11
β-strand	3042	1	12
β-strand	3045	1	12
β-strand	3046-3047	2	11
β-strand	3052-3058	7	11
β-strand	3066-3068	3	11
β-strand	3071-3074	4	11
β-strand	3077-3078	2	11
β-strand	3084-3091	8	11
β-strand	3093	1	11
β-strand	3097-3105	9	11
β-strand	3114-3122	9	11
β-strand	3131	1	13
β-strand	3148	1	13
β-strand	3166-3168	3	11
β-strand	3170-3174	5	11
β-strand	3337-3344	8	11
β-strand	3349-3357	9	11
β-strand	3363-3365	3	11
β-strand	3382-3389	8	11
β-strand	3392-3398	7	11
β-strand	3409	1	14
β-strand	3416	1	15
β-strand	3421	1	15
β-strand	3425	1	14
β-strand	3428-3433	6	14
β-strand	3436-3444	9	14
β-strand	3453-3465	13	14
β-strand	3472-3475	4	14
β-strand	3478-3485	8	14
β-strand	3490-3503	14	14
β-strand	3504	1	16
β-strand	3507	1	16
β-strand	3512-3515	4	14
β-strand	3518-3520	3	14
β-strand	3527-3529	3	14
β-strand	3532-3536	5	14
β-strand	3543-3548	6	14
β-strand	3551-3553	3	14
β-strand	3559-3563	5	14
β-strand	3565-3573	9	14
β-strand	3577-3582	6	14
β-strand	3585-3592	8	14
β-strand	3595-3602	8	14
β-strand	3604	1	17
β-strand	3608	1	14
β-strand	3616	1	17
β-strand	3617-3619	3	18
β-strand	3620-3625	6	14
β-strand	3629	1	18
β-strand	3631	1	14
β-strand	3634-3638	5	18
β-strand	3643-3652	10	18
β-strand	3656-3665	10	18
β-strand	3702-3706	5	18
β-strand	3709-3711	3	18
β-strand	3882-3884	3	18
β-strand	3887-3890	4	18

Chain B: 27 helices, 21 β-strands

Element	Residues	Length	Sheet
α-helix	18-22	5
α-helix	48-50	3
β-strand	61-64	4	23
α-helix	65-72	8
α-helix	92-97	6
β-strand	99-100	2	24
β-strand	103-104	2	24
β-strand	106-108	3	23
β-strand	112-113	2	25
β-strand	115-119	5	26
β-strand	123	1	26
β-strand	129	1	27
α-helix	130-132	3
α-helix	133-142	10
β-strand	146-148	3	26
α-helix	155-162	8
α-helix	183-185	3
α-helix	187-201	15
α-helix	211-216	6
β-strand	223-228	6	26
α-helix	230-236	7
β-strand	243-246	4	26
α-helix	247-249	3
β-strand	250	1	27
β-strand	251	1	28
β-strand	254	1	28
β-strand	259-261	3	25
β-strand	263-266	4	23
α-helix	274-277	4
α-helix	278-285	8
α-helix	290-297	8
α-helix	309-313	5
α-helix	316-326	11
β-strand	329-330	2	25
α-helix	331-332	2
α-helix	336-353	18
α-helix	358-369	12
α-helix	375-387	13
α-helix	389-391	3
α-helix	392-406	15
α-helix	419-427	9
α-helix	435-447	13
α-helix	452-468	17
β-strand	483-488	6	29
β-strand	493-498	6	29
α-helix	503-517	15
β-strand	523-526	4	30
β-strand	531-534	4	30

Chain H: 2 helices, 20 β-strands

Element	Residues	Length	Sheet
β-strand	3-7	5	1
β-strand	12	1	2
β-strand	18-25	8	1
β-strand	33-39	7	3
β-strand	46-51	6	3
β-strand	58-60	3	3
β-strand	68-73	6	1
β-strand	78-83	6	1
α-helix	88-90	3
β-strand	92-99	8	3
β-strand	113	1	3
β-strand	117-119	3	3
β-strand	121	1	2
α-helix	125-126	2
β-strand	151-155	5	4
β-strand	160-163	4	5
β-strand	175	1	6
β-strand	179-180	2	4
β-strand	186-189	4	4
β-strand	190	1	6
β-strand	206-210	5	5
β-strand	215-219	5	5

Chain L: 4 helices, 16 β-strands

Element	Residues	Length	Sheet
β-strand	4-6	3	19
β-strand	19-25	7	19
β-strand	39-44	6	20
α-helix	49-50	2
β-strand	51-55	5	20
β-strand	58	1	20
β-strand	69-72	4	19
β-strand	77-81	5	19
β-strand	91-96	6	20
β-strand	102-103	2	20
β-strand	107-108	2	20
β-strand	121-123	3	21
α-helix	124-126	3
α-helix	127-131	5
β-strand	137-140	4	21
β-strand	167	1	21
α-helix	170-172	3
β-strand	181-184	4	21
β-strand	197-199	3	22
β-strand	212-214	3	22

Chain N: 1 helix, 12 β-strands

Element	Residues	Length	Sheet
β-strand	6-7	2	31
β-strand	10-13	4	32
β-strand	17	1	33
β-strand	20-22	3	31
β-strand	33-39	7	32
β-strand	46-51	6	32
β-strand	58-60	3	32
β-strand	70-73	4	31
β-strand	78-81	4	31
β-strand	84	1	33
α-helix	88-90	3
β-strand	92-99	8	32
β-strand	116-122	7	32

Chain R: 8 helices, 12 β-strands

Element	Residues	Length	Sheet
α-helix	85-87	3
β-strand	113-115	3	34
α-helix	116	1
β-strand	121-123	3	34
α-helix	124-126	3
α-helix	138-141	4
β-strand	152-154	3	35
β-strand	160-162	3	35
β-strand	166	1	36
β-strand	171	1	36
α-helix	185-188	4
β-strand	203	1	37
β-strand	209	1	37
α-helix	212-214	3
β-strand	240-242	3	38
β-strand	248-250	3	38
β-strand	283	1	39
β-strand	289	1	39
α-helix	322-324	3
α-helix	339-341	3

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Legobody 8D3 Fab Heavy Chain	H	protein	234	Mus musculus
Apolipoprotein B 100	A	protein	4563	Homo sapiens	P04114
Legobody 8D3 Fab light chain	L	protein	219	Mus musculus
Maltose/maltodextrin-binding periplasmic protein,Immunoglobulin G-binding protein A,Immunoglobulin…	B	protein	545	Escherichia coli, Staphylococcus aureus, Streptococcus sp. 'group G'	P02976 (AlphaFold model), P0AEX9 (AlphaFold model), P19909 (AlphaFold model)
ApoB100 nanobody 4	N	protein	131	Camelus bactrianus
Low-density lipoprotein receptor	R	protein	860	Homo sapiens	P01130

Sequence of entity 1 (H), FASTA

>9BDE_1 Legobody 8D3 Fab Heavy Chain (chains H)
DVQLVESGGGLVQPGKSLRLSCAASGFTFSNFGMHWVRQAPEMGLEWVAYISSGSTTKYY
GDTVKGRFTISRDNPKNTLYLQMNSLRSEDTAMYYCARRPLYDGDYGYPMDYWGQGTSVT
VSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVL
QSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCGSHHHHHH

Sequence of entity 2 (A), FASTA

>9BDE_2 Apolipoprotein B 100 (chains A)
MDPPRPALLALLALPALLLLLLAGARAEEEMLENVSLVCPKDATRFKHLRKYTYNYEAES
SSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGKALLKKTKNSE
EFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLD
TVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGISPLALIKGMTRPLSTLIS
SSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVAQVTQTLKLEDTPKINSRFFG
EGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNKLVTELRGLSD
EAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPE
PSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTG
DEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKD
QEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANI
LNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQLYKSVSLPSLDPASAKIEGNLI
FDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALY
WVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRIL
GEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPT
GAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQ
MNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENR
QSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATY
ELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVN
DESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAH
WSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDY
PKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKE
FNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPA
LHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTST
DHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSCDGSLRHKFLDSNIKFSHV
EKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSSFYAKGT
YGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNTAS
LKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLN
SHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGA
SMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSN
DMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSD
LKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQ
GVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVMAPFTMTIDAHTNGNGKLALW
GEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRKSISAALEHKVSALLTPAEQTGT
WKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLTLLDSPIKVPLLLSEPINIIDAL
EMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLENVQRNLK
HINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHAKEKLTALTKKYRITENDIQIAL
DDAKINFNEKLSQLQTYMIQFDQYIKDSYDLHDLKIAIANIIDEIIEKLKSLDEHYHIRV
NLVKTIHDLHLFIENIDFNKSGSSTASWIQNVDTKYQIRIQIQEKLQQLKRHIQNIDIQH
LAGKLKQHIEAIDVRVLLDQLGTTISFERINDILEHVKHFVINLIGDFEVAEKINAFRAK
VHELIERYEVDQQIQVLMDKLVELAHQYKLKETIQKLSNVLQQVKIKDYFEKLVGFIDDA
VKKLNELSFKTFIEDVNKFLDMLIKKLKSFDYHQFVDETNDKIREVTQRLNGEIQALELP
QKAEALKLFLEETKATVAVYLESLQDTKITLIINWLQEALSSASLAHMKAKFRETLEDTR
DRMYQMDIQQELQRYLSLVGQVYSTLVTYISDWWTLAAKNLTDFAEQYSIQDWAKRMKAL
VEQGFTVPEIKTILGTMPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKDLKNIK
IPSRFSTPEFTILNTFHIPSFTIDFVEMKVKIIRTIDQMLNSELQWPVPDIYLRDLKVED
IPLARITLPDFRLPEIAIPEFIIPTLNLNDFQVPDLHIPEFQLPHISHTIEVPTFGKLYS
ILKIQSPLFTLDANADIGNGTTSANEAGIAASITAKGESKLEVLNFDFQANAQLSNPKIN
PLALKESVKFSSKYLRTEHGSEMLFFGNAIEGKSNTVASLHTEKNTLELSNGVIVKINNQ
LTLDSNTKYFHKLNIPKLDFSSQADLRNEIKTLLKAGHIAWTSSGKGSWKWACPRFSDEG
THESQISFTIEGPLTSFGLSNKINSKHLRVNQNLVYESGSLNFSKLEIQSQVDSQHVGHS
VLTAKGMALFGEGKAEFTGRHDAHLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVRF
PLRLTGKIDFLNNYALFLSPSAQQASWQVSARFNQYKYNQNFSAGNNENIMEAHVGINGE
ANLDFLNIPLTIPEMRLPYTIITTPPLKDFSLWEKTGLKEFLKTTKQSFDLSVKAQYKKN
KHRHSITNPLAVLCEFISQSIKSFDRHFEKNRNNALDFVTKSYNETKIKFDKYKAEKSHD
ELPRTFQIPGYTVPVVNVEVSPFTIEMSAFGYVFPKAVSMPSFSILGSDVRVPSYTLILP
SLELPVLHVPRNLKLSLPDFKELCTISHIFIPAMGNITYDFSFKSSVITLNTNAELFNQS
DIVAHLLSSSSSVIDALQYKLEGTTRLTRKRGLKLATALSLSNKFVEGSHNSTVSLTTKN
MEVSVATTTKAQIPILRMNFKQELNGNTKSKPTVSSSMEFKYDFNSSMLYSTAKGAVDHK
LSLESLTSYFSIESSTKGDVKGSVLSREYSGTIASEANTYLNSKSTRSSVKLQGTSKIDD
IWNLEVKENFAGEATLQRIYSLWEHSTKNHLQLEGLFFTNGEHTSKATLELSPWQMSALV
QVHASQPSSFHDFPDLGQEVALNANTKNQKIRWKNEVRIHSGSFQSQVELSNDQEKAHLD
IAGSLEGHLRFLKNIILPVYDKSLWDFLKLDVTTSIGRRQHLRVSTAFVYTKNPNGYSFS
IPVKVLADKFIIPGLKLNDLNSVLVMPTFHVPFTDLQVPSCKLDFREIQIYKKLRTSSFA
LNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEITVPESQLTVSQFTLPKSVSDGIAALDL
NAVANKIADFELPTIIVPEQTIEIPSIKFSVPAGIVIPSFQALTARFEVDSPVYNATWSA
SLKNKADYVETVLDSTCSSTVQFLEYELNVLGTHKIEDGTLASKTKGTFAHRDFSAEYEE
DGKYEGLQEWEGKAHLNIKSPAFTDLHLRYQKDKKGISTSAASPAVGTVGMDMDEDDDFS
KWNFYYSPQSSPDKKLTIFKTELRVRESDEETQIKVNWEEEAASGLLTSLKDNVPKATGV
LYDYVNKYHWEHTGLTLREVSSKLRRNLQNNAEWVYQGAIRQIDDIDVRFQKAASGTTGT
YQEWKDKAQNLYQELLTQEGQASFQGLKDNVFDGLVRVTQEFHMKVKHLIDSLIDFLNFP
RFQFPGKPGIYTREELCTMFIREVGTVLSQVYSKVHNGSEILFSYFQDLVITLPFELRKH
KLIDVISMYRELLKDLSKEAQEVFKAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEM
KFTYLINYIQDEINTIFSDYIPYVFKLLKENLCLNLHKFNEFIQNELQEASQELQQIHQY
IMALREEYFDPSIVGWTVKYYELEEKIVSLIKNLLVALKDFHSEYIVSASNFTSQLSSQV
EQFLHRNIQEYLSILTDPDGKGKEKIAELSATAQEIIKSQAIATKKIISDYHQQFRYKLQ
DFSDQLSDYYEKFIAESKRLIDLSIQNYHTFLIYITELLKKLQSTTVMNPYMKLAPGELT
IIL

Sequence of entity 3 (L), FASTA

>9BDE_3 Legobody 8D3 Fab light chain (chains L)
NIMLTQSPSSLAVSAGERVTMSCKSTQSILYNSNQKTYLAWYQQKPGQSPKLLIYWASTR
ASGVPDRFTGSGSGTDFTLTINSVQPEDLAVYYCHQYLSAWTFGGGTKLEIKRTVAAPSV
FIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSL
SSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Sequence of entity 4 (B), FASTA

>9BDE_4 Maltose/maltodextrin-binding periplasmic protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G (chains B)
MKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDI
IFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNK
DLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIK
DVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSK
VNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPL
GAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDQ
ALAFAQILIMPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNEHQAPKGGSGGAGSGDQ
QSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAGGGSGGGSGGSAV
TTYKLVINGKTLKGETTTKAVDAETAEKAFKQYANDNGVDGVWTYDDATKTFTVTEGSGH
HHHHH

Sequence of entity 5 (N), FASTA

>9BDE_5 ApoB100 nanobody 4 (chains N)
QVQLQESGGGLVQAGGSLRLSCVASGYTDGAVNMGWFRQAPGKDRDWVAAISPGGGLTYY
ADSVKGRFTISQDKAKNTVYLQMNSLKPEDTAIYYCAAARSLAHFKLSQYNYWGQGTQVT
VSSLEHHHHHH

Sequence of entity 6 (R), FASTA

>9BDE_6 Low-density lipoprotein receptor (chains R)
MGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQ
ETCLSVTCKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGK
CISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEW
PQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDE
FQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMAR
DCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQD
PDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYT
SLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLA
VDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPA
KIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILE
DEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQ
PRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVA
TQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQALGDVAGRGN
EKKPSSVRALSIVLPIVLLVFLCLGVFLLWKNWRLKNINSINFDNPVYQKTTEDEVHICH
NQDGYSYPSRQMVSLEDDVA

Ligands and cofactors

ID	Name	Formula	Copies
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose	C8 H15 N O6	5
CA	Calcium ion	Ca	7

Primary citation

Structure of apolipoprotein B100 bound to the low-density lipoprotein receptor. Reimund, M., Dearborn, A.D., Graziano, G. et al. Nature (2025) 638:829-835. DOI 10.1038/s41586-024-08223-0 · PubMed

Other PDB entries of the same protein (UniProt P04114), best resolution first:

9COO 3.73 Å, Nanobody 4 bound to Apolipoprotein B 100
9BD8 4.8 Å, ApoB 100 beta barrel bound to LDLR beta propeller
9BD1 5.4 Å, beta/alpha1 region of ApoB 100
9BDT 5.4 Å, Apolipoprotein B 100 bound to LDL receptor and legobody
9E9R 9.0 Å, The Structure of ApoB100 from Human Low-Density Lipoprotein
9EA7 9.0 Å, The Structure of ApoB100 from Human Low-Density Lipoprotein
9EAG 9.0 Å, The Structure of ApoB100 from Human Low-Density Lipoprotein

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