9FQR: UPF0602 protein C4orf47 homolog
96-nm repeat of axonemal doublet microtubules from bovine sperm. Determined by electron microscopy at 5.0 Å resolution. Released 26 Mar 2025.
- Method
- Electron microscopy
- Resolution
- 5.0 Å
- Organism
- Bos taurus
- Chains
- 1574
- Atoms
- 4,527,463
- Mol. weight
- 86760.19 kDa
- Ligands
- GTP, MG, GDP
- Released
- 26 Mar 2025
Explore 9FQR in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9FQR contains 21,806 α-helices and 13,314 β-strands across 1,554 chains. Residue ranges use sequence positions (label_seq_id) from RCSB, which can differ from the residue numbers in the file. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 0: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 79-89 | 11 | |
Chain 0a: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-21 | 19 | |
| α-helix | 22-34 | 13 | |
| α-helix | 46-57 | 12 | |
| α-helix | 61-88 | 28 | |
| α-helix | 91-105 | 15 | |
| α-helix | 136-157 | 22 | |
Chain 0A: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-22 | 20 | |
| α-helix | 23-38 | 16 | |
| α-helix | 47-55 | 9 | |
| α-helix | 60-88 | 29 | |
| α-helix | 91-105 | 15 | |
| α-helix | 137-139 | 3 | |
| α-helix | 140-156 | 17 | |
Chain 0B: 8 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-22 | 20 | |
| α-helix | 23-38 | 16 | |
| α-helix | 46-55 | 10 | |
| α-helix | 60-88 | 29 | |
| α-helix | 91-106 | 16 | |
| α-helix | 128-132 | 5 | |
| α-helix | 137-139 | 3 | |
| α-helix | 140-156 | 17 | |
Chain 0c: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-22 | 20 | |
| α-helix | 22-36 | 15 | |
| α-helix | 46-56 | 11 | |
| α-helix | 60-88 | 29 | |
| α-helix | 91-106 | 16 | |
| α-helix | 122-126 | 5 | |
| α-helix | 140-157 | 18 | |
Chain 0C: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-22 | 20 | |
| α-helix | 22-35 | 14 | |
| α-helix | 46-55 | 10 | |
| α-helix | 60-86 | 27 | |
| α-helix | 91-105 | 15 | |
| α-helix | 128-132 | 5 | |
| α-helix | 140-156 | 17 | |
Chain 0d: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-22 | 20 | |
| α-helix | 22-36 | 15 | |
| α-helix | 46-57 | 12 | |
| α-helix | 60-88 | 29 | |
| α-helix | 91-105 | 15 | |
| α-helix | 136-157 | 22 | |
Chain 0D: 8 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-22 | 20 | |
| α-helix | 22-37 | 16 | |
| α-helix | 46-55 | 10 | |
| α-helix | 60-86 | 27 | |
| α-helix | 91-105 | 15 | |
| α-helix | 128-133 | 6 | |
| α-helix | 137-139 | 3 | |
| α-helix | 140-156 | 17 | |
1434 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| UPF0602 protein C4orf47 homolog | 0, W, Wh | protein | 309 | Bos taurus | Q2T9M0 (AlphaFold model) |
| Sperm acrosome associated 9 | 0A, 0B, 0C, 0D, 0E, 0F, 0G, 0H, 0Y, 0Z, 0a, 0c, 0d, 0e, 0f, 0g, 0h, 0i, 0j, 0k, CT, CU, CV, CX, CY, CZ, Ca, Cb, Cc, Cd, Ce, Cf, Cg, Ch, Ci, Cj, Ck, El, Em, En, Eo, Ep, Et, Eu, Ev, Ew, Ex, M0, M2, M3, M4, M6, M7, M8, M9, NR, NS, NT, NU, NV, NW, NX, NY, NZ | protein | 224 | Bos taurus | F6S0F4 (AlphaFold model) |
| Chromosome 19 C17orf98 homolog | 1, N, O, T0, Tw | protein | 154 | Bos taurus | E1BC62 (AlphaFold model) |
| Testis specific serine kinase 6 | 2, 4, Ef, XZ, x | protein | 273 | Bos taurus | F1N2S7 (AlphaFold model) |
| EF-hand calcium binding domain 6 | 3, 5, Fm, Gq, Xa, Xb, y, z | protein | 1497 | Bos taurus | G5E5A3 |
| Chromosome 13 C20orf85 homolog | 6, P, Ud | protein | 137 | Bos taurus | Q32KZ8 |
| Cilia and flagella associated protein 77 | 8, R, S, T, U4, VX, Vl, Vy | protein | 284 | Bos taurus | A0A3Q1LJD6 |
| Outer dense fiber of sperm tails 3 | 9, A1, A2, A3, A4, A6, A8, AT, AY, Ai, Au, Av, Aw, BO, BU, BX, Bd, Bf, Bm, Bo, Ju, Jv, Jw, Jx, Jy, Jz, K3, K5 | protein | 254 | Bos taurus | Q2TBH0 |
| ATP6V1F neighbor | A, B, C, Js, K6, M, Ma, U | protein | 176 | Bos taurus | G3X8G1 |
| Tektin-2 | A0, Cq, Cr, Cs, Ct, Cu, Cv, Cw, Cy, E6, E7, E8, E9, FA, Nd, Ne, Nf, Ng, Nh | protein | 430 | Bos taurus | Q2T9Q6 |
| Tektin-3 | A5, A7, By, C2, C3, C4, C5, C7, C8, C9, D6, D7, DO, Dy, EB, F0, F2, F3, F4, F6, GA, Mb, Md, Me, Mf, Mg, Mh, Px, Py | protein | 490 | Bos taurus | A6H782 |
| Tektin-1 | A9, Cm, Cn, Co, Cp, E4, E5, Ez, Nb, Nc | protein | 418 | Bos taurus | Q32KZ9 |
153 more molecules are not listed.
Sequence of entity 1 (0, W, Wh), FASTA
>9FQR_1 UPF0602 protein C4orf47 homolog (chains 0, W, Wh)
MPAEGGKTDMERIGLFSEMEYITVGDKYVSQFNRPFNESASKNRQILPGGSKEMSNLQAG
YFDPHFVRIFEGESYVNPNQVRRRYMMEEAKKNLSKAFLPSNGEKKPCGLGSYYGTIGGP
VPFFSAQSKPKEKYEPPGKNLYTNPGKKGTGYGYANITIGKQFSHSSDLYDAAKLNNKKE
NEEHRRLLKGTAFKLNLYPREYFDTNPYMSEKPLPPIKKVEKKETVGNPFKPSSPGKKAG
GMKAGTFDPYPSHSADPYVVKLKSPSSKSAKVFHPPGGPKSRPIESIMALNVKRALNMKN
YKTASVQSY
Sequence of entity 2 (0A, 0B, 0C, 0D, 0E, 0F, 0G, 0H, 0Y, 0Z, 0a, 0c, 0d, 0e, 0f, 0g, 0h, 0i, 0j, 0k, CT, CU, CV, CX, CY, CZ, Ca, Cb, Cc, Cd, Ce, Cf, Cg, Ch, Ci, Cj, Ck, El, Em, En, Eo, Ep, Et, Eu, Ev, Ew, Ex, M0, M2, M3, M4, M6, M7, M8, M9, NR, NS, NT, NU, NV, NW, NX, NY, NZ), FASTA
>9FQR_2 Sperm acrosome associated 9 (chains 0A, 0B, 0C, 0D, 0E, 0F, 0G, 0H, 0Y, 0Z, 0a, 0c, 0d, 0e, 0f, 0g, 0h, 0i, 0j, 0k, CT, CU, CV, CX, CY, CZ, Ca, Cb, Cc, Cd, Ce, Cf, Cg, Ch, Ci, Cj, Ck, El, Em, En, Eo, Ep, Et, Eu, Ev, Ew, Ex, M0, M2, M3, M4, M6, M7, M8, M9, NR, NS, NT, NU, NV, NW, NX, NY, NZ)
MMNEVKESLRSVEQKYKIFQQQQFTFIGALEHCRENAHDKIRPISSIGQVQSYMEHHCSN
STDRRILLMFLDICSELSKLCQHFEALHAGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPH
DVVNHLSCDEARNHYGGVVSLIPIILDLMKEWVAHSEKLPRKALQQVSEPQAATRATAHA
PQASGTQPQLRKQNCGQLIQNIPKPGGKDQGSSKPPWRPPGGKL
Sequence of entity 3 (1, N, O, T0, Tw), FASTA
>9FQR_3 Chromosome 19 C17orf98 homolog (chains 1, N, O, T0, Tw)
MAHLCACPLRREKGFILDGVAVSTMARSYEHLRPKLWSAIPPYNAQQDCHSRRYFRSRVV
PPILRETDQDHGGTGRDGWIVDYFHIFGQGQRYLNRRNWAGAGHSLQQVTGHDHYNTNLK
AIQGFNGRFGYRRNTPALRHCPSVFGEITRFPLF
Sequence of entity 4 (2, 4, Ef, XZ, x), FASTA
>9FQR_4 Testis specific serine kinase 6 (chains 2, 4, Ef, XZ, x)
MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
LSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGGQARDLFAQIA
GAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASP
EVLLGIPYDPKKYDVWSLGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPDGLELSERC
KALIAELLQFSPSARPSAGQVARNGWLRAGDSG
Sequence of entity 5 (3, 5, Fm, Gq, Xa, Xb, y, z), FASTA
>9FQR_5 EF-hand calcium binding domain 6 (chains 3, 5, Fm, Gq, Xa, Xb, y, z)
MCKMAVVPDWHIICPYTRKFTHSRPHSSPCRVYSRSVFQNMFRPSSSTTVANPILSSLDV
KRILFQKITEKGDELKRAFHLLDTANNMTVTKSELRRVITTFLLPLTREQFQDVLAQIPL
TSSGAVPYLVFLSRFGGIDLNINVIKRGGENEMNGCRTLKDLEAQVGEKIFKNIKTVIKA
LMLIDVNTTGLVQPHELRRVLETFCLKMKDEEYKKFAQHYNIDKDAAVDYNVFLKNLGSN
NDLNLKYNMGSQEVLWENQRVKSFKREEPPSSAVSDNIWKNYSLDEIETAFCLELSKCYE
KVEKALSAGDPCTSGYVSLNYLKIVLDTFVYRLPRRIFIQLMKRFGLKTTTKVNWKQFLT
SFYEPQYEASSKAPLTKRNSINFRNQVHKENVITKLFRHEDHDSSLKKALLLIKSKPDGQ
ITGQELQRILNCMVVKISDSEFRELMRILDPGCTGCVNVSRFIELIEESPKLHKIPAYKD
TKMPLFLAWDSVEEIIHDSIAKNLSAFCNMLRSYDLGDTGLIGRNNFKKIMRVFCPFLTT
EHLVKLCSKFQDIASGRILYKKLLACLGINRPPTVSPVSMPKGQLLNEHLQKEEQPLPDH
SERATPAESQGAVTRNMTKDEVIEKLKSCIQQQDPAFRKRFLDFTKEPNGKIHTHDFKKV
LEDYGMPMDDDQYALLTTKLGYKKEGMSYLDFAAGFEDPKMNEPEVTPPQTPVLPKGDVD
SFFVTAEECLRQFPRRLKEFFRDPYAAFFKMDTDRDGILTMHDLHRLLQHLLFNLKDEEF
ERLLGLLGLRLSITLNFREFRNLCEKRSFSADDDAPQRLPRPKQKVADSELACEQAHQYL
VTKAKTRWSDLSKNFIETDSEGNGILRRRDMKNALYGFDIPLTPREFEKLWMRYDSEGRG
HITYQEFLQKLGINYSADIHRPYAEEYFNFMGHFTKPQQVQEELKELQQSTEKAMPARDK
LKDHDQDISKALAKLDKSRTGYISLGRLQRLLQECGCSLKEEELIDLLNSWGIAWHNNSI
NYLDFLRAVENNKLTRPQSQEKEESVPINFAALSPEEVLKNIQGVIAASSLALSTAFSAL
DKEDTGFVKASDFGQVLKDFCYKLTDNQYHYFLRKLRLHLTPYINWKYFLQNFSSYVEET
AVEWAEKMPRGPRPLSPKEMANQELLARLHKAVTSHYHAIAQEFENFDTMKTNTASRDEF
RSICTRHVQVLTDEQFDRLWEEMPVNSKGRLRYLDFLSSFNVDKQATPLATSDSAKAQRG
SSVPEVSDRGRSAGSSPTRDPKAGSKPRSHPCTPSSVSGTPPLQNCEPIETKLRKKVQGC
WRELLRECKERDFNKQGEIPGPEFLALVEKFNLDISRDECQQLLIKYDLKNNGKFAYCSF
IQSCVLLLKAKETSLMQRMKIQNANKMKEAGAETCSFYSALLRIQPKIVHCWRPMRRTFK
AYDEGGTGLLSVADFRKVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLRAFLQ
Sequence of entity 6 (6, P, Ud), FASTA
>9FQR_6 Chromosome 13 C20orf85 homolog (chains 6, P, Ud)
MAQKPISTAAAERMNLVAQDEIWKYRLKAENEARQNWAQNWGFLSTPFEELIKCEEEPAT
PKPKIELPERFRIRPVTPVEKYIKVLPSPPVPKTTQGFIGWRSGVPGLNKCLEHDYEIRS
CKGAYAKELNWPKQGIH
Sequence of entity 7 (8, R, S, T, U4, VX, Vl, Vy), FASTA
>9FQR_7 Cilia and flagella associated protein 77 (chains 8, R, S, T, U4, VX, Vl, Vy)
MPEARNSCQDLTRWKKKKPPVRRTVSQICPPPRRPLTVADIRPGMENERLGVVRDSMFQN
PLIVKAELGKPRERSCSLPGINFNYGLYIRGLDGGVPEAIGHWNVFKQQPTCPHELTRNY
IAMNRGAVKAGLVTARENLHYRQLNDIRISDQDDRRLKKEPPSLPPNMTFGIRARPSTPF
FDLLQHRYQQLWVQEQKDTQKAIKLEKKHKVILGKLYETRSSQLRKYKPPMGLDTLWHMP
HFQKVGPHLATFPTEADRQRAFKAHREECAVRQGTLRMGNYTHP
Sequence of entity 8 (9, A1, A2, A3, A4, A6, A8, AT, AY, Ai, Au, Av, Aw, BO, BU, BX, Bd, Bf, Bm, Bo, Ju, Jv, Jw, Jx, Jy, Jz, K3, K5), FASTA
>9FQR_8 Outer dense fiber of sperm tails 3 (chains 9, A1, A2, A3, A4, A6, A8, AT, AY, Ai, Au, Av, Aw, BO, BU, BX, Bd, Bf, Bm, Bo, Ju, Jv, Jw, Jx, Jy, Jz, K3, K5)
MAEEVWVGTWRPHRPRGPIMALYSSPGPKYLIPPTTGFVKHTPTKLRAPAYSFRGAPMLL
AENCSPGPRYSVNPKILRTGKDLGPAYSILGRYHTKTTLTPGPGDYFPEKSTKHVFDSAP
SHSISARTKTFRVDSTPGPAAYMLPMVMGPHTIGKVSQPSFSIKGRSKLGSFSDDLHKTP
GPAAYRQTDVQVTKFKAPQYTMAARVEPPGDKTLKPGPGAHSPEKVTMTRPCAPVVSFGI
KHSDYMTPLVVDVD
Sequence of entity 9 (A, B, C, Js, K6, M, Ma, U), FASTA
>9FQR_9 ATP6V1F neighbor (chains A, B, C, Js, K6, M, Ma, U)
MSRQLSMDTVRQNFWKEEYLREKMLRCEWHHKYGSLVKAKQKAKAAARLPLKLPTLPPKA
PLSPPPTPKAVPSRASSPALEAPIQSEMYPVPPATRALLYEGISHDFQGRYRYLSTRKLD
VPEKRYLFPITTNFTYGWQLGPPVKQELVSCKMCRIESFFRKNGAFSLLDPRDLAL
Sequence of entity 10 (A0, Cq, Cr, Cs, Ct, Cu, Cv, Cw, Cy, E6, E7, E8, E9, FA, Nd, Ne, Nf, Ng, Nh), FASTA
>9FQR_10 Tektin-2 (chains A0, Cq, Cr, Cs, Ct, Cu, Cv, Cw, Cy, E6, E7, E8, E9, FA, Nd, Ne, Nf, Ng, Nh)
MATLSVKPSPRFRLPDWQTNSYLLSTNAERQRDASHQIRQEARVLRNETNNQTIWDEHDN
RTRLAERIDTVSRWKEMLDKCLTDLDAEIDALAQMKESAEQNLQAKNLPLDVAIECLTLR
ESRRDIDVVKDPVEEELHKEVEVIEATKKALQQKISQAFEKLFLLQEARQRLNSDHRGKM
ETLDIDRGCLSLNLTSPNISLKINPTRVPNGSTSLQQWDDLSRFNKDHGEAEMKKAIELR
EAIALTIAETNNELEAQRVATEFAFRKRLREMEKLYSELKWQEKNTLEEIAELHEDIRHL
EEDLRRKLQNLKLCHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQ
DALDALYKHLARLQADIACKANSMLLDTKCMDTRRKLTVPAEKFVPEVDTFTRTTNRTLS
PLKTCQLELA
Sequence of entity 11 (A5, A7, By, C2, C3, C4, C5, C7, C8, C9, D6, D7, DO, Dy, EB, F0, F2, F3, F4, F6, GA, Mb, Md, Me, Mf, Mg, Mh, Px, Py), FASTA
>9FQR_11 Tektin-3 (chains A5, A7, By, C2, C3, C4, C5, C7, C8, C9, D6, D7, DO, Dy, EB, F0, F2, F3, F4, F6, GA, Mb, Md, Me, Mf, Mg, Mh, Px, Py)
MELLGSTLTATYAHPRPTPTNFLPAISTMASTYRDRFPHYNLTHSLSLPWRPSTYYKAAS
NWPTLDPYCTRSQRVSESTMLPFVSNRTTLFTRYTPDDWYRSNLTNFQESNTSRHNSERL
RVDTSRLIQDKYQQTRKTQADSTQNLGERVNDIGFWKSEIIHELDAMIGETNELTDIKKR
LERALMETEAPLQVARECLFHREKRMGIDLVHDEVEKELLTEVDTILCCQERMKLYLDKA
IAQLAANRAAQHELEKDLSDKQSAYRIDDKCHHLRNTSDGVSYFHGVERVDATVSVPESW
AKFTDDNILRSQSERAASAKLRDDIQNVLVVTANEMWNQFNKVNLAFTNRIAETADAKNK
IQTHLAKTLQEIFQTEMTIESIKKAIVEKSAFLKVAQTRLDERTRRPNIELCRDMAQLRL
VNEVYEVDDTIQTLQQRLRDAEDTLQSLAHTKATLEHDLAVKANSLYIDQDKCMSMRRSF
PSTLRLVGFC
Sequence of entity 12 (A9, Cm, Cn, Co, Cp, E4, E5, Ez, Nb, Nc), FASTA
>9FQR_12 Tektin-1 (chains A9, Cm, Cn, Co, Cp, E4, E5, Ez, Nb, Nc)
MAKLLQQPPKFLRAEWQIANKNQYHRAEAQRSRSERLVAESQRLVDEIEKTTRKSQSDVN
KKLEQRLEEVRFWKKELDDKLEQLVYATEDLLLYQTRLQKALESFKEPLHITEKCLEYRE
KRVGIDLVHDEVEQELIKEHEIIRGVMTLLTRTLEETCEQIRLNRSAKYNLEKDLRDKFT
AITIDDICFSLNNNSPNIKYSENVVRVEPNSVSLEDWLDFSNTNVEKADKQRNNSLTLKA
LVDRILFQTASDLRRQCDVVDTAFKNGLKETKDARDKLALHLDKVMEEIASQEKNIVVLE
KAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLIKEVDEITHNVARLKETLAQAHV
ELKGLNRRQLALQEEIQIKENTIYIDEVLCVPMRKSIPPRDGDDHGEWAGGSHPEAVC
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 342 |
| MG | Magnesium ion | Mg | 345 |
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 345 |
Primary citation
Structural diversity of axonemes across mammalian motile cilia. Leung, M.R., Sun, C., Zeng, J. et al. Nature (2025) 637:1170-1177. DOI 10.1038/s41586-024-08337-5 · PubMed
Other PDB entries of the same protein (UniProt Q2T9M0 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8OTZ 3.6 Å, 48-nm repeat of the native axonemal doublet microtubule from bovine sperm
Browse structure collections
About this viewer
MolViewer shows 9FQR directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.