9JIH: BAR domain of ACAP4

Crystal structure of BAR domain of ACAP4. Determined by X-ray diffraction at 2.8 Å resolution. Released 14 Jan 2026.

Method: X-ray diffraction
Resolution: 2.8 Å
Organism: Homo sapiens
Chains: 2
Atoms: 4,175
Mol. weight: 63.58 kDa
Released: 14 Jan 2026

Explore 9JIH in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9JIH contains 17 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 9 helices, 0 β-strands

Element	Residues	Length
α-helix	5-19	15
α-helix	22-89	68
α-helix	93-120	28
α-helix	121-125	5
α-helix	126-134	9
α-helix	136-161	26
α-helix	180-205	26
α-helix	206-210	5
α-helix	211-276	66

Chain B: 8 helices, 0 β-strands

Element	Residues	Length
α-helix	4-19	16
α-helix	22-89	68
α-helix	93-120	28
α-helix	121-125	5
α-helix	126-132	7
α-helix	137-163	27
α-helix	179-207	29
α-helix	209-277	69

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3	A, B	protein	282	Homo sapiens	Q8TDY4 (AlphaFold model)

Sequence of entity 1 (A, B), FASTA

>9JIH_1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (chains A, B)
GPGSEFVAEFLAVTAEDLSSPAGAAAFAAKMPRYRGAALAREEILEGDQAILQRIKKAVR
AIHSSGLGHVENEEQYREAVESLGNSHLSQNSHELSTGFLNLAVFTREVAALFKNLIQNL
NNIVSFPLDSLMKGQLRDGRQDSKKQLEKAWKDYEAKMAKLEKERDRARVTGGIPGEVAQ
DMQRERRIFQLHMCEYLLKAGESQMKQGPDFLQSLIKFFHAQHNFFQDGWKAAQSLFPFI
EKLAASVHALHQAQEDELQKLTQLRDSLRGTLQLESREEHLS

Primary citation

BAR-PH tandem of ACAP4 remodels membranes to drive migration via Ezrin-dependent activation. Huang, S., Chen, J., Wang, X. et al. J Mol Cell Biol (2026) 17. DOI 10.1093/jmcb/mjaf038 · PubMed

Other PDB entries of the same protein (UniProt Q8TDY4 (AlphaFold model), which also has an AlphaFold model), best resolution first:

2B0O 2.06 Å, Crystal structure of UPLC1 GAP domain
3LVQ 3.38 Å, The crystal structure of ASAP3 in complex with Arf6 in transition state
3LVR 3.38 Å, The crystal structure of ASAP3 in complex with Arf6 in transition state soaked with…

Browse structure collections

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