Structure of the Rattus norvegicus ACE2 receptor bound HsItaly2011 RBD complex. Determined by electron microscopy at 2.5 Å resolution. Released 27 Aug 2025.
Explore 9N7D in 3D Show helices and sheets RCSB PDB PDBe
9N7D contains 50 α-helices and 31 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 20-51 | 32 | |
| α-helix | 56-80 | 25 | |
| α-helix | 91-100 | 10 | |
| α-helix | 104-107 | 4 | |
| α-helix | 110-129 | 20 | |
| β-strand | 131-133 | 3 | 1 |
| β-strand | 141-143 | 3 | 1 |
| β-strand | 147 | 1 | 1 |
| α-helix | 148-154 | 7 | |
| α-helix | 158-168 | 11 | |
| α-helix | 169-173 | 5 | |
| α-helix | 174-192 | 19 | |
| α-helix | 199-203 | 5 | |
| α-helix | 204-207 | 4 | |
| β-strand | 209 | 1 | 2 |
| β-strand | 217 | 1 | 2 |
| α-helix | 221-251 | 31 | |
| β-strand | 260 | 1 | 3 |
| α-helix | 261 | 1 | |
| β-strand | 262-263 | 2 | 4 |
| α-helix | 264-266 | 3 | |
| α-helix | 276-281 | 6 | |
| α-helix | 294-299 | 6 | |
| α-helix | 304-317 | 14 | |
| α-helix | 320-324 | 5 | |
| α-helix | 325-330 | 6 | |
| β-strand | 332 | 1 | 5 |
| β-strand | 347-352 | 6 | 5 |
| β-strand | 355-359 | 5 | 5 |
| α-helix | 366-384 | 19 | |
| α-helix | 390-392 | 3 | |
| α-helix | 400-412 | 13 | |
| α-helix | 415-420 | 6 | |
| α-helix | 432-464 | 33 | |
| α-helix | 470-472 | 3 | |
| α-helix | 473-480 | 8 | |
| α-helix | 481-485 | 5 | |
| β-strand | 487-488 | 2 | 4 |
| α-helix | 500-502 | 3 | |
| α-helix | 504-507 | 4 | |
| α-helix | 514-532 | 19 | |
| α-helix | 539-541 | 3 | |
| α-helix | 548-558 | 11 | |
| α-helix | 566-574 | 9 | |
| α-helix | 582-587 | 6 | |
| α-helix | 589-598 | 10 | |
| β-strand | 607 | 1 | 3 |
| β-strand | 618-622 | 5 | 6 |
| α-helix | 637-658 | 22 | |
| α-helix | 667-669 | 3 | |
| β-strand | 670-673 | 4 | 6 |
| β-strand | 680-685 | 6 | 6 |
| β-strand | 686 | 1 | 7 |
| β-strand | 694 | 1 | 7 |
| α-helix | 695-696 | 2 | |
| α-helix | 697-706 | 10 | |
| α-helix | 708-715 | 8 | |
| β-strand | 722-724 | 3 | 6 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 392-396 | 5 | |
| α-helix | 402-404 | 3 | |
| β-strand | 406-410 | 5 | 8 |
| β-strand | 414 | 1 | 9 |
| α-helix | 417-421 | 5 | |
| β-strand | 425-431 | 7 | 8 |
| α-helix | 436-440 | 5 | |
| β-strand | 444 | 1 | 10 |
| β-strand | 446-453 | 8 | 8 |
| α-helix | 456-462 | 7 | |
| α-helix | 469 | 1 | |
| α-helix | 470-474 | 5 | |
| β-strand | 483-489 | 7 | 8 |
| β-strand | 501-512 | 12 | 11 |
| β-strand | 516-519 | 4 | 11 |
| α-helix | 521-523 | 3 | |
| α-helix | 531-534 | 4 | |
| β-strand | 543-547 | 5 | 11 |
| β-strand | 552-560 | 9 | 11 |
| α-helix | 561-562 | 2 | |
| β-strand | 566-574 | 9 | 8 |
| β-strand | 582 | 1 | 10 |
| β-strand | 583 | 1 | 9 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Angiotensin-converting enzyme 2 | A | protein | 767 | Rattus norvegicus | Q5EGZ1 (AlphaFold model) |
| Spike glycoprotein | B | protein | 271 | Merbecovirus | A3EXD0 (AlphaFold model) |
>9N7D_1 Angiotensin-converting enzyme 2 (chains A) MSSSCWLLLSLVAVATAQSLIEEKAESFLNKFNQEAEDLSYQSSLASWNYNTNITEENAQ KMNEAAAKWSAFYEEQSKIAQNFSLQEIQNATIKRQLKALQQSGSSALSPDKNKQLNTIL NTMSTIYSTGKVCNSMNPQECFLLEPGLDEIMATSTDYNRRLWAWEGWRAEVGKQLRPLY EEYVVLKNEMARANNYEDYGDYWRGDYEAEGVEGYNYNRNQLIEDVENTFKEIKPLYEQL HAYVRTKLMEVYPSYISPTGCLPAHLLGDMWGRFWTNLYPLTTPFLQKPNIDVTDAMVNQ SWDAERIFKEAEKFFVSVGLPQMTPGFWTNSMLTEPGDDRKVVCHPTAWDLGHGDFRIKM CTKVTMDNFLTAHHEMGHIQYDMAYAKQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKS IGLLPSNFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFQDKIPREQWTKKWWEM KREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALCQAAKHDGPLH KCDISNSTEAGQKLLNMLSLGNSGPWTLALENVVGSRNMDVKPLLNYFQPLFVWLKEQNR NSTVGWSTDWSPYADQSIKVRISLKSALGKNAYEWTDNEMYLFRSSVAYAMREYFSREKN QTVPFGEADVWVSDLKPRVSFNFFVTSPKNVSDIIPRSEVEEAIRMSRGRINDIFGLNDN SLEFLGIYPTLKPPYEPPVTIGLNDIFEAQKIEWHEGGSHHHHHHHH
>9N7D_2 Spike glycoprotein (chains B) MGILPSPGMPALLSLVSLLSVLLMGCVAETGTECDFSKLFKAAPPQIYNFSRLVFTNCNY NLTKLLSLFHVSEFSCHQVSPSALASGCYSSLTVDYFAYPLYLASYLQQGSTGEIAQYNY KQDFSNPTCRILASVPANVSIPKPDKYIWLSQCYSFSAYSGDVPHYVLPGQYTPCLYLTS SGFDNSYQTNRDFQNKMAATGVISSMTDNLQMAFVISVQYGTDTNSVCPMQALRLVPRGS SSGGSGLNDIFEAQKIEWHEGGSHHHHHHHH
ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution. Liu, C., Park, Y.J., Ma, C.B. et al. bioRxiv (2025). DOI 10.1101/2025.02.19.639017 · PubMed
Other PDB entries of the same protein (UniProt Q5EGZ1 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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