9R3T: C-terminal domain of SdeA Legionella effector

C-terminal domain of SdeA Legionella effector. Determined by X-ray diffraction at 1.98 Å resolution. Released 20 May 2026.

Method: X-ray diffraction
Resolution: 1.98 Å
Organism: Legionella pneumophila
Chains: 1
Atoms: 2,642
Mol. weight: 39.97 kDa
Released: 20 May 2026

Explore 9R3T in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9R3T contains 12 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 12 helices, 0 β-strands

Element	Residues	Length
α-helix	1164-1193	30
α-helix	1199-1225	27
α-helix	1237-1266	30
α-helix	1270-1272	3
α-helix	1273-1291	19
α-helix	1298-1365	68
α-helix	1390-1408	19
α-helix	1415-1423	9
α-helix	1427-1434	8
α-helix	1438-1452	15
α-helix	1458-1475	18
α-helix	1480-1482	3

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Ubiquitinating/deubiquitinating enzyme SdeA	A	protein	346	Legionella pneumophila	Q5ZTK4 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>9R3T_1 Ubiquitinating/deubiquitinating enzyme SdeA (chains A)
GSHMDFSDVEKLEQQIQVIDTKLADAYLLEVTKQISALDNTKPKNQTELKTKIAAFLDRT
TDIEMLRNERIKKHGSSKDPLDLSDLDKLSGSLQRINQSLVSDLITTIRVSINQMEAKTF
HEQEKEIQQNFELLAKLEKTLDKSKTSEKLREDIPKLNDLLVAKQKAYPQMVQMQLKSEV
FVTQLREVCQANHDDLDKTRNARLRELDRLDREAGITRMVGNLIWGLTNKVGLTTDERLD
IRTKQQSLARFKNELFNDKIDTDQLISNLARKRPSELQEGLGISTDNAMELHLLLTELAG
KTTSPDELEERMKAIDDISTKIGREPEHLKFVMVEEDESNKKTIGF

Primary citation

Structural Basis for Membrane Targeting and Secretion of Legionella SidE Ubiquitin Ligases. Misra, M., Mukherjee, R., Bhattacharya, A. et al. To be published.

Other PDB entries of the same protein (UniProt Q5ZTK4 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5YSI 1.55 Å, SdeA mART-C domain EE/AA NCA complex
5YSJ 2.06 Å, SdeA mART-C domain WT apo
6B7Q 2.2 Å, Crystal structure of Legionella effector protein sdeA (lpg2157) aa. 211-910
5YSK 2.4 Å, SdeA mART-C domain EE/AA apo
7MIR 2.5 Å, Cryo-EM structure of SidJ-SdeA-CaM reaction intermediate complex
6WTG 2.63 Å, SdeA DUB Domain in complex with Ubiquitin
6G0C 2.8 Å, Crystal structure of SdeA catalytic core
8EFW 2.81 Å, Structure of SdeA DUB Domain disulfide crosslinked with Ubiquitin
7PPO 2.91 Å, Structure of SidJ/CaM bound to SdeA in pre-glutamylation state
7PQE 3.7 Å, Structure of SidJ/CaM bound to SdeA in post-catalysis state

Browse structure collections

About this viewer

MolViewer shows 9R3T directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.