9T8H: Murine RNF213

Murine RNF213 bound to maltoheptaose. Determined by electron microscopy at 3.0 Å resolution. Released 23 Sept 2026.

Method
Electron microscopy
Resolution
3.0 Å
Organism
Mus musculus
Chains
1
Atoms
36,555
Mol. weight
590.59 kDa
Ligands
ZN, ATP
Released
23 Sept 2026

Explore 9T8H in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9T8H contains 285 α-helices and 116 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain B: 285 helices, 116 β-strands

ElementResiduesLengthSheet
β-strand347-356101
β-strand368-37362
α-helix375-3773
β-strand38712
β-strand388-39361
α-helix395-3973
β-strand399-408101
α-helix409-4113
β-strand416-42382
β-strand432-43432
β-strand449-45242
α-helix456-4583
β-strand463-47191
α-helix489-51022
α-helix511-5133
α-helix518-53518
β-strand539-54242
β-strand544-54742
α-helix549-5513
α-helix555-57420
α-helix579-5813
α-helix591-60414
α-helix611-62111
α-helix623-6242
α-helix628-6347
α-helix636-6416
α-helix642-65817
α-helix663-6675
α-helix668-6736
α-helix677-6804
α-helix689-6935
α-helix700-7045
α-helix712-7198
α-helix721-7255
α-helix730-7356
α-helix740-74910
α-helix751-7566
α-helix758-7603
α-helix761-7699
α-helix781-80121
α-helix802-8065
α-helix811-82818
α-helix832-8343
α-helix836-85015
α-helix864-88825
β-strand894-89633
β-strand901-90333
α-helix908-9169
α-helix922-9243
α-helix926-93914
α-helix943-9519
α-helix953-9553
α-helix963-98119
α-helix995-100915
β-strand101214
β-strand101714
α-helix1021-103010
α-helix1033-104311
α-helix1046-10505
α-helix1053-107523
β-strand107915
α-helix1080-10889
α-helix1090-110213
α-helix1113-114331
β-strand1149-115026
α-helix1154-11607
β-strand116715
β-strand117317
β-strand118317
α-helix1191-120313
α-helix1207-122115
β-strand1231-123226
α-helix1234-12374
α-helix1238-12425
α-helix1243-125816
β-strand126218
α-helix1263-12697
α-helix1270-12734
α-helix1277-128812
α-helix1296-132934
α-helix1336-13383
α-helix1339-135113
β-strand135518
α-helix1361-13677
α-helix1369-13724
α-helix1375-138612
α-helix1388-139710
α-helix1401-141414
α-helix1419-143416
α-helix1436-14394
α-helix1448-146316
α-helix1468-147710
α-helix1479-14835
α-helix1496-150611
β-strand1508-151149
α-helix1518-15203
α-helix1522-15254
β-strand1526-153169
β-strand1540-154349
α-helix1545-155713
α-helix1559-15602
α-helix1564-159229
β-strand1602-160659
β-strand1612-161659
β-strand1625-162739
α-helix1631-165929
α-helix1662-16654
α-helix1668-167811
α-helix1685-16917
α-helix1700-171011
α-helix1713-173119
α-helix1736-174914
α-helix1751-17544
α-helix1761-177313
β-strand1780110
α-helix1782-17843
β-strand1791111
β-strand1794-1797411
α-helix1799-181012
α-helix1817-18193
β-strand1824-1826311
α-helix1833-184412
β-strand1851110
β-strand1853-1857511
α-helix1859-18613
α-helix1864-187815
β-strand1887-1893711
α-helix1894-18963
α-helix1900-19045
α-helix1906-19083
β-strand1909111
α-helix1913-19142
α-helix1918-192912
α-helix1938-19403
β-strand1948-1953612
α-helix1960-197516
β-strand1982-1987612
β-strand1991113
α-helix1994-20018
α-helix2002-20043
α-helix2007-20115
β-strand2015-2020612
β-strand2026113
α-helix2028-20325
α-helix2033-20375
β-strand2040-2042314
β-strand2048-2050314
β-strand2056-2062712
α-helix2080-20856
β-strand2090-2092312
α-helix2096-21027
α-helix2117-21215
α-helix2123-213614
α-helix2155-216511
α-helix2173-219220
α-helix2208-221912
α-helix2221-22244
β-strand2266-2269415
β-strand2276-2279415
β-strand2282-2285416
β-strand2290117
β-strand2291-2294416
β-strand2301-2303316
β-strand2308117
α-helix2309-23179
α-helix2326-23283
α-helix2331-234212
α-helix2358-237316
β-strand2377-2380418
α-helix2387-239913
β-strand2408-2411418
α-helix2418-243821
β-strand2443-2448618
α-helix2450-24523
α-helix2456-24605
α-helix2461-24655
β-strand2467-2468219
β-strand2471-2472219
α-helix2473-24742
β-strand2479-2485718
β-strand2490120
α-helix2491-24922
α-helix2493-25008
β-strand2516-2517221
β-strand2520-2521221
α-helix2522-25243
β-strand2525120
α-helix2531-25333
β-strand2541-2542218
α-helix2548-256215
α-helix2570-258718
α-helix2599-261416
α-helix2616-263015
α-helix2633-26364
α-helix2641-265010
α-helix2651-26555
α-helix2661-26699
α-helix2679-269618
α-helix2698-26992
α-helix2707-272216
α-helix2724-27252
β-strand2726-2730522
α-helix2737-274610
β-strand2748122
α-helix2749-27513
α-helix2755-27584
β-strand2762-2769822
α-helix2776-279015
β-strand2798-2805822
α-helix2807-28104
α-helix2817-28204
α-helix2821-28277
α-helix2836-28383
β-strand2841-2846622
α-helix2852-28554
β-strand2859-2863522
α-helix2864-28663
α-helix2868-287912
α-helix2883-28897
α-helix2890-28923
α-helix2893-290513
α-helix2914-293118
α-helix2937-294812
α-helix2956-29627
α-helix2965-29673
α-helix2975-29839
α-helix3000-30012
β-strand3002-3006523
α-helix3011-30144
α-helix3015-30195
α-helix3024-30252
β-strand3026-3028323
α-helix3038-305518
β-strand3059-3061323
α-helix3064-307613
β-strand3087-3092624
β-strand3095-3100624
β-strand3107-3112623
α-helix3113-31186
α-helix3122-31276
β-strand3129-3132423
α-helix3135-31384
α-helix3141-315818
β-strand3160125
α-helix3173-31764
β-strand3177126
β-strand3179127
α-helix3184-319411
α-helix3203-321816
β-strand3221126
α-helix3223-32286
α-helix3229-32313
β-strand3232125
α-helix3236-32449
α-helix3245-32495
α-helix3255-32628
β-strand3272-3279828
α-helix3282-32843
α-helix3286-329510
β-strand3304-3307428
α-helix3314-332613
β-strand3331-3339928
α-helix3346-33483
α-helix3350-336314
β-strand3370-3378928
α-helix3384-33874
β-strand3389127
β-strand3396-3400528
β-strand3410129
α-helix3414-34185
α-helix3422-34254
α-helix3471-34744
β-strand3475129
α-helix3477-349014
β-strand3492-3494330
α-helix3502-351211
α-helix3518-353922
α-helix3544-35474
α-helix3549-35557
α-helix3557-35637
α-helix3566-358924
α-helix3591-35933
α-helix3596-35994
α-helix3605-361511
β-strand3636131
β-strand3639-3641330
α-helix3647-36482
α-helix3658-367518
α-helix3681-36899
α-helix3693-36997
α-helix3703-372119
α-helix3727-374620
α-helix3762-37709
α-helix3772-378413
α-helix3788-37925
α-helix3808-382215
α-helix3829-384719
α-helix3849-38524
α-helix3857-387923
α-helix3880-38845
α-helix3885-38895
α-helix3892-38943
α-helix3895-391016
α-helix3918-393922
β-strand3957-3960432
β-strand3964-3967432
α-helix3968-39725
β-strand3981133
β-strand3988133
α-helix3999-402224
α-helix4023-40275
α-helix4036-404611
β-strand4047134
α-helix4048-40503
β-strand4064134
β-strand4075134
β-strand4079-4081335
α-helix4083-40897
α-helix4093-411018
α-helix4118-413821
α-helix4143-415614
α-helix4172-419524
α-helix4200-42023
α-helix4203-421816
α-helix4222-424423
α-helix4250-42545
α-helix4257-42626
α-helix4272-42765
α-helix4278-429316
α-helix4297-43059
α-helix4310-432112
α-helix4322-43265
α-helix4327-43293
α-helix4343-435210
α-helix4359-437012
α-helix4374-43774
α-helix4383-440220
α-helix4406-44083
α-helix4409-44157
α-helix4418-44214
β-strand4449-4450236
β-strand4456-4457236
β-strand4503137
α-helix4512-45154
α-helix4523-454321
α-helix4545-45517
β-strand4552137
α-helix4559-457820
α-helix4582-459817
α-helix4614-463320
α-helix4635-464713
α-helix4650-46534
α-helix4656-46616
α-helix4673-46742
α-helix4687-46904
α-helix4692-470110
α-helix4704-47074
α-helix4709-47168
α-helix4718-47214
α-helix4722-47265
α-helix4727-474115
β-strand4751138
α-helix4752-47587
α-helix4762-478827
β-strand4808138
α-helix4809-48113
α-helix4818-48203
α-helix4821-484525
β-strand4852-4854339
α-helix4855-48573
α-helix4860-48623
α-helix4868-48725
α-helix4873-48786
β-strand4880-4885635
β-strand4890-4894535
α-helix4896-49038
α-helix4904-49085
β-strand4913-4915339
β-strand4928131
α-helix4930-494011
α-helix4945-49473
α-helix4948-495710
α-helix4961-498121
β-strand4988140
α-helix4989-49913
α-helix4992-49965
α-helix5004-50096
α-helix5010-50123
β-strand5014140
α-helix5015-50173
α-helix5018-503518
α-helix5046-50483
α-helix5050-50534
α-helix5054-506411
α-helix5069-508214
β-strand5098141
α-helix5099-510911
α-helix5115-51217
β-strand5127141
α-helix5128-51303
α-helix5131-514717

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
E3 ubiquitin-protein ligase RNF213Bprotein5188Mus musculusE9Q555
Sequence of entity 1 (B), FASTA
>9T8H_1 E3 ubiquitin-protein ligase RNF213 (chains B)
MASWSHPQFEKGSAGSAAGSGAGWSHPQFEKENLYFQAMSMECPQCGHVSSEKAPKFCSE
CGQKLPSAATVQGDLKNDNTLVVSSTPEGKTEQGAVLREEEVLLSSTDPGKELEKPEESD
SNASWTTQMSKKEKRRRKRQGTISSSEAPSSGLWSLDMPPSPGSHNSALPQNQAQQGGAA
SQPGHPLDTENMPMEDGFVHTEGSGSPLQGQAAERTDAQSNLAPSDLAEVKDLNTSKPSV
DKGLPLDGGPALSAFKGHPKMTDASQKAPLPESKGETSGQEKKVPPIDAAASPVKTAGKE
TGEDVRKPKPSPVSPVASKHGDQEAELKGKLATPVRKSNEGGNTQPEDQRKPGEGRNFAA
AVKTQQAAAPQQAAAPEPTSAFNPRDTVTVYFHAIVSRHFGFNPEEHKVYVRGGEGLGQK
GWTDACEMYCTQDLHDLGSLVEGKMDIPRQSLDKPIPYKYVIHRGGSSKDTVEYEFIYEQ
AQKKGEHVNRCLRVVSTSLGNGDWHQYDDIICMRSTGFFQQAKNRILDSTRKELLKGKKQ
AAVVMLDRIFSVLQPWSDINLQSFMTQFLQFYSVVREPMIHDGRARKWTSLQYEEKEVWT
NLWEHVKKQMAPFLEGKSGESLPADCPVRSKLTLGLSILFMVEAAEFTVPKKDLDSLCYL
LIPSAGSPEALHSDLSPVLRIRQRWRIYLTNLCLRCIDERCDRWLGILPLLHTCMQKSPP
KKNSKSQPEDTWAGLEGISFSEFRDKAPTRSQPLQFMQSKMALLRVDEYLFRSWLSVVPL
ESLSSYLENSIDYLSDVPVRVLDCLQGISYRLPGLRKISNQNMKKDVENVFKMLMHLVDI
YQHRIFGENLLQIYLTECLTLHETVCNITANHQFFEIPALSAELICKLLELSPPGHTDEG
LPEKSYEDLVTSTLQEALATTRNWLRSLFKSRMLSISSAYVRLTYSEEMAVWRRLVEIGF
PEKHGWKGSLLGDMEGRLKQEPPRLQISFFCSSQCRDGGLHDSVSRSFEKCVIEAVSSAC
QSQTSVLEGLSCQDLQKFGTLLSAVITKSWPVHNGEPVFDVDEIFKYLLKWPDVRQLFEL
CGTNEKIIDNITEEGRQLMATAESVFQKVAGELENGTIVVGQLELILEHQSQFLDIWNLN
RRRLPSQEKACDVRSLLKRRRDDLLFLKQEKRYVESLLRQLGRVKHLVQVDFGNIEIIHS
QDLSNKKLNEAVIKLPNSSSYKRETHYCLSPDIREMASKLDSLKDSHIFQDFWQETAESL
NTLDKDPRELKVSLPEVLEYLYNPCYDNFYTLYENLKSGKITFAEVDAIFKDFVDKYDEL
KNDLKFMCTMNPQDQKGWISERVGQIKEYHTLHQAVSSAKVILQVRRALGVTGDFSVLNP
LLNFADSFEDFGNEKLDQISPQFIKAKQLLQDISEPRQRCLEELARQTELVAWLHKALED
INELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKMDERTNFSDFMNHLQELWR
ALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGVYVIEAPKDGQKI
SPDTVLRLLLPDGHGYPEALRTYSTEELKELLNKLMLMSGKKDHNSNTEVEKFSEVFSNM
QRLVHVFIKLHCAGNMLFRTWTAKVYCCPDGGIFMNFGLELLSQLTEKGDVIQLLGALCR
QMEDFLDNWKTVVAQKRAEHFYLNFYTAEQLVYLSSELRKPRPSEAALMMLSFIKGKCTV
QDLVQATSACESKADRYCLREVMKKLPQQLLSEPSLMGKLQVIMMQSLVYMSAFLPHCLD
LDALGRCLAHLATMGGTPVERPLPKGLQAGQPNLILCGHSEVLPAALAIYMQAPRQPLPT
FDEVLLCTPATTIEEVELLLRRCLTSGSQGHKVYSLLFADQLSYEVGCQAEEFFQSLCTR
AHREDYQLVILCDAAREHCYIPSTFSQYKVPLVPQAPLPNIQAYLQSHYQVPKRLLSAAT
VFRDGLCVGIVTSERAGVGKSLYVNTLHTKLKAKLRDETVPLKIIRLTEPHLDENQVLSA
LLPFLKEKYQKMPVIFHIDISTSVQTGIPIFLFKLLILQYLMDINGKIWRRSPGHLYLVE
IPQGLSVQPKRSSKLNARAPLFKFLDLFPKVTCRPPKEVIDMELTPERSHTDPAMDPVEF
CSEAFQRPYQYLKRFHQQQNLDTFQYEKGSVEGSPEECLQHFLIYCGLINPSWSELRNFA
WFLNCQLKDCEASIFCKSAFTGDTLRGFKNFVVTFMILMARDFATPTLHTSDQSPGRQSV
TIGEVVEEDLAPFSLRKRWESEPHPYVFFNGDHMTMTFIGFHLETNNNGYVDAINPSNGK
VIKKDVMTKELFDGLRLQRVPFNIDFDNLPRYEKLERLCLALGIEWPIDPDETYELTTDN
MLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLKRGSVEAETMKLVKVHGGTTPSM
IYSKVKEAERTAFSNKAQHKLDTILFFDEANTTEAVSCIKEILCDRTVDGEHLHEDSGLH
IIAACNPYRKHSQEMILRLESAGLGYRVSAEETADRLGSIPLRQLVYRVHALPPSLIPLV
WDFGQLNDSAEKLYIQQIVQRLVDSVSVNPSETCVIADVLSASQMFMRKRENECGFVSLR
DVERCVKVFRWFHDHSDMLLKELDKFLHESSDSTHTFERDPVLWSLVMAIGVCYHASLEE
KASYRTAIARCFPKPYNSSRAILDEVTHVQDLFLRGAPIRTNIARNLALKENVFMMVICI
ELKIPLFLVGKPGSSKSLAKIIVADAMQGQAAFSELFRCLKQVHLVSFQCSPHSTPQGII
STFKQCARFQQGKDLGQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPYKKV
GFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDKIRGYFAPFAKAY
ETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKRGLSPQDITHAVLRNFSGKDNIQALSIF
TASLPEARYKEEVSTVELIKQNIYPGPQASSRGLDGAESRYLLVLTRNYVALQILQQTFF
EGQQPEIIFGSSFPQDQEYTQICRNINRVKICMETGKMVVLLNLQNLYESLYDALNQYYV
YLGGQKYVDLGLGTHRVKCRVHTAFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQ
PWQKSIVQELQQWAHEFADVKADQFIARHKYSPADVFIGYHSDACASVVLQAVERQGCRD
LTEELYRKVSEEARSILLDCATPDAVVRLSGSSLGSFTAKQLSQEYYYAQQHNSFVDFLQ
AHLRMTHHECRAVFTEITTFSRLLTGNDCDVLASELRGLASKPVVLSLQQYDTEYSFLKD
VRSWLTNPGKRKVLVIQADFDDGTRSAQLVASAKYTAINEINKTQGTKDFVFVYFVTKLS
RMGSGTSYVGFHGGLWRSVHIDDLRRSTIMASDVTKLQNVTISQLFKPEDKPEQEEMEIE
TSQSKELAEEQMEVEDSEEMKKASDPRSCDCSQFLDTTRLVQSCVQGAVGMLRDQNESCA
RNMRRVTILLDLLNEDNTRNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDAL
QEAGTFRHTLWKRVQDVVTPILASMIAHIDRDGNLELLAQPDSPAWVQDLWMFIYSDIKF
LNISLVLNNTRSNSEMSFILVQSHMNLLKDAYNAVPFSWRIRDYLEELWVQAQYITDTEG
LSKKFVEIFQKTPLGVFLAQFPVAQQQKLLQSYLKDFLLLTMKVSSREELMFLQMALWSC
LRELQEASGTPDETYKFPLSLPWVHLAFQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHS
LAGCEMTLDAFAAMACAEMLKGDLLKPSPKAWLQLVKNLSTPLELVCSEGYLCDSGSMTR
SVIQEVRALWNRIFSIALFVEHVLLGTESHIPELSPLVTTYVSLLDKCLEEDSNLKTCRP
FVAVMTTLCDCKDKASKKFSRFGIQPCFICHGDAQDPVCLPCDHVYCLRCIQTWLIPGQM
MCPYCLTDLPDKFSPTVSQDHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNTPPEKSVID
TLLSLLFVQKELLRDASQKHREHTKSLSPFDDVVDQTPVIRSVLLKLLLKYSFHEVKDYI
QNYLTQLEKKAFLTEDKTELYLLFISCLEDSVHQKTSAGCRNLEQVLREEGHFLRTYSPG
LQGQEPVRIASVEYLQEVARVRLCLDLAADFLSELQEGSELAEDKRRFLKHVEEFCTRVN
NDWHRVYLVRKLSSQRGMEFVQSFSKQGHPCQWVFPRKVIAQQKDHVSLMDRYLVHGNEY
KAVRDATAKAVLECKTLDIGNALMACRSPKPQQTAYLLLALYTEVAALYRSPNGSLHPEA
KQLEAVNKFIKESKILSDPNIRCFARSLVDNTLPLLKIRSANSILKGTVTEMAVHVATIL
LCGHNQILKPLRNLAFYPVNMANAFLPTMPEDLLVHARTWRGLENVTWYTCPRGHPCSVG
ECGRPMQESTCLDCGLPVGGLNHTPHEGFSAIRNNEDRTQTGHVLGSPQSSGVAEVSDRG
QSPVVFILTRLLTHLAMLVGATHNPQALTVIIKPWVQDPQGFLQQHIQRDLEQLTKMLGR
SADETIHVVHLILSSLLRVQSHGVLNFNAELSTKGCRNNWEKHFETLLLRELKHLDKNLP
AINALISQDERISSNPVTKIIYGDPATFLPHLPQKSIIHCSKIWSCRRKITVEYLQHIVE
QKNGKETVPVLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSRVEYSSIRGFIHSHS
SDGLRKLLHDRITIFLSTWNALRRSLETNGEIKLPKDYCCSDLDLDAEFEVILPRRQGLG
LCGTALVSYLISLHNNMVYTVQKFSNEDNSYSVDISEVADLHVISYEVERDLNPLILSNC
QYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNK
MAQSSLPNLAISTISGQLQS

Ligands and cofactors

IDNameFormulaCopies
ZNZinc ionZn2
ATPAdenosine-5'-triphosphateC10 H16 N5 O13 P31

Primary citation

Quality control of glycogen through direct ubiquitylation by RNF213. Yip, M.C.J., Naydenova, K., Otten, E.G. et al. Nature (2026). DOI 10.1038/s41586-026-11139-6 · PubMed

Other PDB entries of the same protein (UniProt E9Q555), best resolution first:

Browse structure collections

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