Proliferating cell nuclear antigen (KXV57_008947) is a 871-residue protein from Aspergillus fumigatus. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A229Y5V5.
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The mean pLDDT of this model is 72.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 30% |
| 70 to 90 | Confident: backbone generally right | 34% |
| 50 to 70 | Low: treat with caution | 17% |
| Below 50 | Very low: often disordered regions | 19% |
What pLDDT means and how to read it
Confers DNA tethering and processivity to DNA polymerases and other proteins. Auxiliary protein of DNA polymerase delta and epsilon, is involved in the control of DNA replication by increasing the polymerases' processivity during elongation of the leading strand. Additionally, acts as a molecular switch to control the choice of two parallel branches of the DNA damage tolerance (DDT) pathway (also known as the post-replication repair (PRR) pathway) that bypasses replication-blocking lesions without removing them; the translesion DNA synthesis (TLS) branch, and the template-switching (TS) branch; monoubiquitinated PCNA promotes the TLS branch and polyubiquitinated PCNA promotes the TS branch
Endomembrane system, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
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