MHC class I antigen (HLA-A) is a 371-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A583ZB34.
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The mean pLDDT of this model is 84.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 72% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 17% |
What pLDDT means and how to read it
Cell membrane, Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7OW4 | X-ray | 1.81 Å | A/D/G/J=25-299 |
| 8RYN | X-ray | 1.97 Å | A=25-299 |
| 8WTE | X-ray | 2.17 Å | E/H=25-299 |
| 8WUL | X-ray | 2.36 Å | I/L/O/R=25-298 |
| 7OW3 | X-ray | 2.46 Å | A/D/G/J=25-299 |
| 8RYQ | X-ray | 2.49 Å | A/F=25-299 |
| 7OW5 | X-ray | 2.58 Å | A=25-299 |
| 7OW6 | X-ray | 2.64 Å | A=25-299 |
| 7PB2 | X-ray | 3.41 Å | A/F=25-299 |
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