Guanine nucleotide-binding protein G(s) subunit alpha (GNAS) is a 285-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A804HIH4.
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The mean pLDDT of this model is 92.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 76% |
| 70 to 90 | Confident: backbone generally right | 21% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9BIP | EM | 2.8 Å | A=1-64 |
| 9GGG | EM | 3.25 Å | A=6-64 |
| 9JFT | EM | 3.27 Å | A=1-64 |
| 9K25 | EM | 3.31 Å | A=6-64 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.