Guanine nucleotide-binding protein subunit alpha (GNAQ) is a 359-residue protein from Theropithecus gelada. This is its AlphaFold structure prediction, created 31 Mar 2025. UniProt accession: A0A8D2GGC9.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 90.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 73% |
| 70 to 90 | Confident: backbone generally right | 22% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts (GDP-bound form) with RIC8A (via C-terminus); promoting GNAQ folding and association with the plasma membrane. Binds NHERF1. Forms a complex with PECAM1 and BDKRB2. Interacts with GAS2L2. Interacts with CCKBR
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9B5Y | EM | 3.49 Å | A=7-359 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.