Histone H2B (LOC108704302) is a 126-residue protein from Xenopus laevis. This is its AlphaFold structure prediction, created 31 Mar 2025. UniProt accession: A0A8J1LZU9.
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The mean pLDDT of this model is 83.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 66% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 28% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
Chromosome, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8VMJ | EM | 3.1 Å | M/S=31-126 |
| 8A3Y | EM | 3.3 Å | d=32-126 |
| 8VMN | EM | 3.5 Å | M/S=31-126 |
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