C1FUH4: Protein OrfX2 (orfX2)

Protein OrfX2 (orfX2) is a 750-residue protein from Clostridium botulinum (strain Kyoto / Type A2). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: C1FUH4.

Gene
orfX2
Organism
Clostridium botulinum (strain Kyoto / Type A2)
Length
750 residues
Mean pLDDT
90.9
Model
AF-C1FUH4-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate75%
70 to 90Confident: backbone generally right21%
50 to 70Low: treat with caution3%
Below 50Very low: often disordered regions1%

What pLDDT means and how to read it

Function

Part of a botulinum neurotoxin type A2 (BoNT) locus; may be part of a progenitor toxin complex required to protect BoNT during its passage through the host gastrointestinal tract (Probable). Binds phosphatidylinositol (3,4) bisphosphate, phosphatidylethanolamine and phosphatidylserine (PubMed:29067689)

Subunit structure

Part of a crude toxin extract that includes BoNTA2/NTNH, P47, OrfX2 and OrfX3; OrfX1 was not detected

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6EKVX-ray2.1 ÅA=1-750
9ARLEM4.0 ÅC=1-750
9ARKEM4.1 ÅC=1-748

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