D4A055: Voltage-dependent L-type calcium channel subunit beta-4 (Cacnb4)

Voltage-dependent L-type calcium channel subunit beta-4 (Cacnb4) is a 519-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: D4A055.

Gene
Cacnb4
Organism
Rattus norvegicus
Length
519 residues
Mean pLDDT
72.0
Model
AF-D4A055-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 72.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate48%
70 to 90Confident: backbone generally right6%
50 to 70Low: treat with caution8%
Below 50Very low: often disordered regions38%

What pLDDT means and how to read it

Function

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting

Subunit structure

The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with FASLG (By similarity). Interacts with CBARP (By similarity)

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6HW2X-ray1.94 ÅA=56-232
1VYVX-ray3.0 ÅA/B=49-407

More AlphaFold highlights

About this viewer

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