Rho-related GTP-binding protein RhoD (RHOD) is a 210-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O00212.
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The mean pLDDT of this model is 89.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 80% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 9% |
What pLDDT means and how to read it
Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution
Interacts (in GTP-bound form) with DIAPH2 isoform 3 (PubMed:12577064). Interacts (in GTP-bound form) with DAPK3 (PubMed:23454120). Interacts (in GTP-bound form) with FILIP1 (PubMed:12577064). Interacts (in GTP-bound form) with WHAMM (By similarity). Interacts with PAK5 (PubMed:17064668). Interacts (independent of GTP-loaded status) with ANKFY1 (PubMed:24102721). Interacts with PLXNB2…
Cell membrane, Early endosome
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