O14625: C-X-C motif chemokine 11 (CXCL11)

C-X-C motif chemokine 11 (CXCL11) is a 94-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O14625.

Gene
CXCL11
Organism
Homo sapiens
Length
94 residues
Mean pLDDT
79.9
Model
AF-O14625-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 79.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate1%
70 to 90Confident: backbone generally right84%
50 to 70Low: treat with caution15%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses

Subunit structure

Interacts with TNFAIP6 (via Link domain)

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9P0MEM2.95 ÅB=22-94
8HNKEM3.01 ÅL=1-94
1RJTNMRA=22-94

More AlphaFold highlights

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