O85042: Carboxysome shell carbonic anhydrase (csoS3)

Carboxysome shell carbonic anhydrase (csoS3) is a 514-residue protein from Halothiobacillus neapolitanus (strain ATCC 23641 / c2). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O85042.

Gene
csoS3
Organism
Halothiobacillus neapolitanus (strain ATCC 23641 / c2)
Length
514 residues
Mean pLDDT
92.7
Model
AF-O85042-F1 v6
Model created
1 Aug 2025
PDB structures
13

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Model confidence (pLDDT)

The mean pLDDT of this model is 92.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate89%
70 to 90Confident: backbone generally right4%
50 to 70Low: treat with caution1%
Below 50Very low: often disordered regions6%

What pLDDT means and how to read it

Function

Reversible hydration of carbon dioxide (PubMed:14729686, PubMed:17012396, PubMed:18258595). Essential for chemolithotrophic carbon dioxide fixation, supplies CO(2) to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable) (PubMed:18258595). There are estimated to be 40 CsoSCA dimers per carboxysome (Ref.5)

Subunit structure

Homodimer, may form filaments

Subcellular location

Carboxysome

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7SMKEM1.98 ÅC=1-50
9SKUEM2.06 ÅA/B=2-514
7SNVEM2.07 ÅC=1-50
9SKXEM2.08 ÅA/B=2-514
9SKVEM2.12 ÅA/B=2-514
9SKREM2.13 ÅA/B=2-514
9SKSEM2.15 ÅA/B=2-514
9SKYEM2.18 ÅA/B=2-514
2FGYX-ray2.2 ÅA/B=1-514
9SKZEM2.22 ÅA/B=2-514
9SKWEM2.27 ÅA/B=2-514
9SKTEM2.45 ÅA/B=2-514
9G4TEM2.51 ÅA=2-514

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