Carboxysome shell carbonic anhydrase (csoS3) is a 514-residue protein from Halothiobacillus neapolitanus (strain ATCC 23641 / c2). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O85042.
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The mean pLDDT of this model is 92.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 89% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 6% |
What pLDDT means and how to read it
Reversible hydration of carbon dioxide (PubMed:14729686, PubMed:17012396, PubMed:18258595). Essential for chemolithotrophic carbon dioxide fixation, supplies CO(2) to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable) (PubMed:18258595). There are estimated to be 40 CsoSCA dimers per carboxysome (Ref.5)
Homodimer, may form filaments
Carboxysome
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7SMK | EM | 1.98 Å | C=1-50 |
| 9SKU | EM | 2.06 Å | A/B=2-514 |
| 7SNV | EM | 2.07 Å | C=1-50 |
| 9SKX | EM | 2.08 Å | A/B=2-514 |
| 9SKV | EM | 2.12 Å | A/B=2-514 |
| 9SKR | EM | 2.13 Å | A/B=2-514 |
| 9SKS | EM | 2.15 Å | A/B=2-514 |
| 9SKY | EM | 2.18 Å | A/B=2-514 |
| 2FGY | X-ray | 2.2 Å | A/B=1-514 |
| 9SKZ | EM | 2.22 Å | A/B=2-514 |
| 9SKW | EM | 2.27 Å | A/B=2-514 |
| 9SKT | EM | 2.45 Å | A/B=2-514 |
| 9G4T | EM | 2.51 Å | A=2-514 |
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