26S proteasome complex subunit SEM1 (SEM1) is a 89-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O94742.
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The mean pLDDT of this model is 72.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 11% |
| 70 to 90 | Confident: backbone generally right | 37% |
| 50 to 70 | Low: treat with caution | 51% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Versatile protein that might stabilize multiple protein complexes involved in diverse pathways. Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Also associates with the TREX-2 complex that is required for transcription-coupled mRNA export, and the COP9 signalosome, which is involved in deneddylation
Part of the 26S proteasome. Associates with the nuclear pore complex (NPC)-associated TREX-2 complex and the COP9 signalosome. Interacts with CSN12 and THP3
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5UBP | X-ray | 2.3 Å | C=1-89 |
| 8U8C | X-ray | 2.4 Å | C=1-89 |
| 7EWF | X-ray | 2.85 Å | C=1-89 |
| 3T5V | X-ray | 2.9 Å | C/F=1-89 |
| 7EWM | X-ray | 2.9 Å | C=1-89 |
| 8U8D | EM | 3.04 Å | C=1-89 |
| 4TRQ | X-ray | 3.1 Å | C/F=30-89 |
| 8U8E | EM | 3.33 Å | C=1-89 |
| 3JCK | EM | 3.5 Å | I=1-89 |
| 9CGC | EM | 3.61 Å | Y=1-89 |
| 6J2Q | EM | 3.8 Å | Y=1-89 |
| 6J2X | EM | 3.8 Å | Y=1-89 |
| 5MPD | EM | 4.1 Å | Y=1-89 |
| 6FVT | EM | 4.1 Å | Y=1-89 |
| 5WVK | EM | 4.2 Å | Y=1-89 |
| 5MPE | EM | 4.5 Å | Y=1-89 |
| 6FVU | EM | 4.5 Å | Y=1-89 |
| 6FVW | EM | 4.5 Å | Y=1-89 |
| 6J30 | EM | 4.5 Å | Y=1-89 |
| 3JCP | EM | 4.6 Å | Y=1-89 |
Showing 20 of 39 experimental structures (best resolution first).
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