O95149: Snurportin-1 (SNUPN)

Snurportin-1 (SNUPN) is a 360-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O95149.

Gene
SNUPN
Organism
Homo sapiens
Length
360 residues
Mean pLDDT
82.8
Model
AF-O95149-F1 v6
Model created
1 Aug 2025
PDB structures
11

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Model confidence (pLDDT)

The mean pLDDT of this model is 82.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate58%
70 to 90Confident: backbone generally right22%
50 to 70Low: treat with caution6%
Below 50Very low: often disordered regions13%

What pLDDT means and how to read it

Function

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs

Subunit structure

Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Component of a nuclear export receptor complex composed of KPNB1, Ran, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, Ran and XPO1. Interacts (via IBB domain) with KPNB1; the interaction is direct. Interacts with DDX20, IPO7, SMN1, SNRPB and XPO1. Interacts directly with XPO1. Its interaction with…

Subcellular location

Nucleus, Cytoplasm

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2P8QX-ray2.35 ÅB=25-64
1XK5X-ray2.4 ÅA=97-300
3GJXX-ray2.5 ÅB/E=1-360
3NBZX-ray2.8 ÅB/E=15-360
2QNAX-ray2.84 ÅB=1-66
5DISX-ray2.85 ÅC=1-287
3GB8X-ray2.9 ÅB=1-328
3NC0X-ray2.9 ÅB/E=15-360
3LWWX-ray3.15 ÅB/D=25-64
2Q5DX-ray3.2 ÅC/D=25-64
3NBYX-ray3.42 ÅB/E=15-360

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