Catalase (CAT) is a 527-residue protein from Bos taurus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00432.
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The mean pLDDT of this model is 95.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 95% |
| 70 to 90 | Confident: backbone generally right | 1% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide (PubMed:10691967). Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells (PubMed:10691967)
Homotetramer (PubMed:10417406). Interacts (via microbody targeting signal) with PEX5, monomeric form interacts with PEX5, leading to its translocation into peroxisomes (By similarity)
Peroxisome matrix
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6PO0 | X-ray | 1.75 Å | A/B/C/D=1-527 |
| 6PM7 | X-ray | 1.85 Å | A/B=1-527 |
| 3RGP | X-ray | 1.88 Å | A/B/C/D=4-502 |
| 3RE8 | X-ray | 1.9 Å | A/B/C/D=4-502 |
| 3RGS | X-ray | 1.99 Å | A/B/C/D=4-502 |
| 4BLC | X-ray | 2.3 Å | A/B/C/D=2-507 |
| 7CAT | X-ray | 2.5 Å | A/B=2-507 |
| 8CAT | X-ray | 2.5 Å | A/B=2-507 |
| 3NWL | X-ray | 2.69 Å | A/B/C/D=1-527 |
| 1TGU | X-ray | 2.8 Å | A/B/C/D=2-507 |
| 1TH2 | X-ray | 2.8 Å | A/B/C/D=2-507 |
| 1TH3 | X-ray | 2.8 Å | A/B/C/D=2-507 |
| 1TH4 | X-ray | 2.98 Å | A/B/C/D=2-507 |
| 6JNT | EM | 3.0 Å | A/B/C/D=1-527 |
| 6JNU | EM | 3.0 Å | A/B/C/D=1-527 |
| 3J7B | EM | 3.2 Å | A/B/C/D=1-527 |
| 5GKN | EM | 3.2 Å | A/B/C/D=1-527 |
| 7DI8 | EM | 3.2 Å | A/B/C/D=1-527 |
| 9BDJ | EM | 4.0 Å | A/B/C/D=1-527 |
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