ATP-dependent 6-phosphofructokinase (pfkA) is a 319-residue protein from Geobacillus stearothermophilus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00512.
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The mean pLDDT of this model is 96.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 94% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Homotetramer
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4I7E | X-ray | 2.0 Å | A/B/C/D=1-319 |
| 4I36 | X-ray | 2.3 Å | A/B/C/D=1-319 |
| 3PFK | X-ray | 2.4 Å | A=1-319 |
| 4PFK | X-ray | 2.4 Å | A=1-319 |
| 4I4I | X-ray | 2.49 Å | A/B/C/D=1-319 |
| 6PFK | X-ray | 2.6 Å | A/B/C/D=1-319 |
| 3U39 | X-ray | 2.79 Å | A/B/C/D=1-319 |
| 1MTO | X-ray | 3.2 Å | A/B/C/D/E/F/G/H=1-319 |
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