Alkaline phosphatase (phoA) is a 471-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00634.
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The mean pLDDT of this model is 96.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 95% |
| 70 to 90 | Confident: backbone generally right | 0% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Isozymes 1 and 3 are a dimer of identical chains, isozyme 2 is a dimer of heterogeneous chains, one of each of the subunits from isozymes 1 and 3
Periplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3TG0 | X-ray | 1.2 Å | A/B/C/D=23-471 |
| 3BDF | X-ray | 1.4 Å | A/B=22-471 |
| 3BDG | X-ray | 1.4 Å | A/B=22-471 |
| 1Y6V | X-ray | 1.6 Å | A/B=23-471 |
| 1ED8 | X-ray | 1.75 Å | A/B=23-471 |
| 1ED9 | X-ray | 1.75 Å | A/B=23-471 |
| 1Y7A | X-ray | 1.77 Å | A/B=23-471 |
| 7N6M | X-ray | 1.82 Å | B=273-282 |
| 3BDH | X-ray | 1.85 Å | A/B=22-471 |
| 1B8J | X-ray | 1.9 Å | A/B=23-471 |
| 1ALK | X-ray | 2.0 Å | A/B=23-471 |
| 1EW9 | X-ray | 2.0 Å | A/B=23-471 |
| 1KH5 | X-ray | 2.0 Å | A/B=23-471 |
| 2G9Y | X-ray | 2.0 Å | A/B=23-471 |
| 7N6J | X-ray | 2.0 Å | B=1-19 |
| 5C66 | X-ray | 2.03 Å | A/B=23-471 |
| 1URA | X-ray | 2.04 Å | A/B=26-471 |
| 3CMR | X-ray | 2.05 Å | A/B=23-471 |
| 1URB | X-ray | 2.14 Å | A/B=26-471 |
| 1ALI | X-ray | 2.2 Å | A/B=23-471 |
Showing 20 of 74 experimental structures (best resolution first).
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