Ribulose bisphosphate carboxylase large chain (rbcL) is a 475-residue protein from Spinacia oleracea. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00875.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 97.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 97% |
| 70 to 90 | Confident: backbone generally right | 1% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process (Probable) (PubMed:2928307). Both reactions occur simultaneously and in competition at the same active site (Probable). Binds to abscisic acid (ABA) which has weakly inhibits carboxylation and more strongly inhibits enzyme activation (PubMed:26197050)
Heterohexadecamer of 8 large chains and 8 small chains
Plastid, chloroplast
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8RUC | X-ray | 1.6 Å | A/C/E/G=1-475 |
| 1IR1 | X-ray | 1.8 Å | A/B/C/D=1-475 |
| 1AA1 | X-ray | 2.2 Å | B/E/H/L=1-475 |
| 1AUS | X-ray | 2.2 Å | L/M/N/O=1-475 |
| 1RXO | X-ray | 2.2 Å | B/E/H/L=1-475 |
| 1RBO | X-ray | 2.3 Å | B/E/H/L=1-475 |
| 1RCO | X-ray | 2.3 Å | B/E/H/K/L/O/R/V=1-475 |
| 1UPM | X-ray | 2.3 Å | B/E/H/K/L/O/R/V=1-475 |
| 1UPP | X-ray | 2.3 Å | A/C/E/G=1-475 |
| 8QJ0 | X-ray | 2.3 Å | L/M/N/O=1-475 |
| 1RCX | X-ray | 2.4 Å | B/E/H/K/L/O/R/V=1-475 |
| 9CQ5 | X-ray | 2.5 Å | A/B/C/D/E/F/G/H=1-475 |
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