Triosephosphate isomerase (TPI1) is a 248-residue protein from Gallus gallus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00940.
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The mean pLDDT of this model is 97.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 97% |
| 70 to 90 | Confident: backbone generally right | 2% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis
Homodimer
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4P61 | X-ray | 1.34 Å | A/B=1-248 |
| 1SW0 | X-ray | 1.71 Å | A/B=1-248 |
| 1TPH | X-ray | 1.8 Å | 1/2=2-248 |
| 1TPB | X-ray | 1.9 Å | 1/2=2-248 |
| 1TPC | X-ray | 1.9 Å | 1/2=2-248 |
| 1TPU | X-ray | 1.9 Å | A/B=2-248 |
| 1TPV | X-ray | 1.9 Å | A/B=2-248 |
| 1TPW | X-ray | 1.9 Å | A/B=2-248 |
| 1SW3 | X-ray | 2.03 Å | A/B=1-248 |
| 1SPQ | X-ray | 2.16 Å | A/B=2-248 |
| 1SW7 | X-ray | 2.22 Å | A/B=1-248 |
| 1TIM | X-ray | 2.5 Å | A/B=2-248 |
| 8TIM | X-ray | 2.5 Å | A/B=2-248 |
| 1SU5 | X-ray | 2.7 Å | A/B=2-248 |
| 1SQ7 | X-ray | 2.85 Å | A/B=2-248 |
| 1SSD | X-ray | 2.9 Å | A/B=2-248 |
| 1SSG | X-ray | 2.9 Å | A/B=2-248 |
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