P00980: Kunitz-type serine protease inhibitor homolog alpha-dendrotoxin

Kunitz-type serine protease inhibitor homolog alpha-dendrotoxin is a 59-residue protein from Dendroaspis angusticeps. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P00980.

Organism
Dendroaspis angusticeps
Length
59 residues
Mean pLDDT
93.9
Model
AF-P00980-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 93.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate90%
70 to 90Confident: backbone generally right5%
50 to 70Low: treat with caution3%
Below 50Very low: often disordered regions2%

What pLDDT means and how to read it

Function

Serine protease inhibitor homolog that blocks voltage-gated potassium channels (Kv1.1/KCNA1, Kv1.2/KCNA2, and Kv1.6/KCNA6) (IC(50)=0.4-150 nM) and facilitates neurotransmitter release

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
1DTXX-ray2.2 ÅA=1-59
8VC3EM3.2 ÅA=2-59

More AlphaFold highlights

About this viewer

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