ATPase inhibitor, mitochondrial (ATP5IF1) is a 109-residue protein from Bos taurus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P01096.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 78.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 48% |
| 70 to 90 | Confident: backbone generally right | 18% |
| 50 to 70 | Low: treat with caution | 19% |
| Below 50 | Very low: often disordered regions | 15% |
What pLDDT means and how to read it
Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase (PubMed:10831597, PubMed:12923572, PubMed:17895376, PubMed:18687699, PubMed:21192948, PubMed:7397110). Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme…
Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0
Mitochondrion
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2V7Q | X-ray | 2.1 Å | J=26-85 |
| 1GMJ | X-ray | 2.2 Å | A/B/C/D=26-109 |
| 1OHH | X-ray | 2.8 Å | H=26-109 |
| 4TSF | X-ray | 3.2 Å | H/I=26-85 |
| 4TT3 | X-ray | 3.21 Å | H/I/J=26-85 |
| 6YY0 | EM | 3.23 Å | J=26-85 |
| 6Z1R | EM | 3.29 Å | J=26-85 |
| 6ZQM | EM | 3.29 Å | J=26-85 |
| 4Z1M | X-ray | 3.3 Å | H/I/J=26-85 |
| 9W2R | EM | 3.4 Å | J=26-85 |
| 6Z1U | EM | 3.47 Å | J=26-85 |
| 6ZPO | EM | 4.0 Å | J=26-85 |
| 6ZQN | EM | 4.0 Å | J=26-85 |
| 9W2S | EM | 4.0 Å | J=26-85 |
| 5LQZ | EM | 7.0 Å | J=26-85 |
| 5LQY | EM | 7.8 Å | J=26-85 |
| 5LQX | EM | 7.9 Å | J=26-85 |
| 7AJF | EM | 8.45 Å | AJ/J=26-109 |
| 7AJD | EM | 9.0 Å | AJ/J=26-85 |
| 7AJB | EM | 9.2 Å | AJ/J=26-85 |
Showing 20 of 27 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.