P05745: Large ribosomal subunit protein eL36A (RPL36A)

Large ribosomal subunit protein eL36A (RPL36A) is a 100-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P05745.

Gene: RPL36A
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length: 100 residues
Mean pLDDT: 92.3
Model: AF-P05745-F1 v6
Model created: 1 Aug 2025
PDB structures: 222

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Model confidence (pLDDT)

The mean pLDDT of this model is 92.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT band	Meaning	Share of residues
Above 90	Very high: backbone and side chains are usually accurate	79%
70 to 90	Confident: backbone generally right	19%
50 to 70	Low: treat with caution	2%
Below 50	Very low: often disordered regions	0%

What pLDDT means and how to read it

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion…

Subunit structure

Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554)

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB ID	Method	Resolution	Chains and residues
8CCS	EM	1.97 Å	U=1-100
8CDR	EM	2.04 Å	U=1-100
8CEH	EM	2.05 Å	U=1-100
8P8N	EM	2.15 Å	RI=1-100
8PFR	EM	2.15 Å	RI=1-100
8EVT	EM	2.2 Å	Ai=1-100
8T2Y	EM	2.2 Å	Ai=1-100
8P8U	EM	2.23 Å	RI=1-100
8CGN	EM	2.28 Å	U=1-100
8ZHC	EM	2.3 Å	Lk=2-100
7UOO	EM	2.34 Å	i=1-100
7V08	EM	2.36 Å	i=1-100
8EVP	EM	2.38 Å	Ai=1-100
7TOP	EM	2.4 Å	AL36=1-100
7ZW0	EM	2.4 Å	Ll=1-100
8AGX	EM	2.4 Å	V=1-100
8BN3	EM	2.4 Å	O6=2-100
8T2Z	EM	2.4 Å	Ai=1-100
7UQB	EM	2.43 Å	i=1-100
7UQZ	EM	2.44 Å	i=2-100

Showing 20 of 222 experimental structures (best resolution first).

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