Citrate synthase, peroxisomal (CIT2) is a 460-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P08679.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 94.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 94% |
| 70 to 90 | Confident: backbone generally right | 2% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Peroxisomal citrate synthase involved in the citrate homeostasis (PubMed:25982115, PubMed:3023912). Catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate (PubMed:25982115, PubMed:3023912). Citrate synthase is the rate-limiting enzyme of the tricarboxylic acid (TCA) cycle (Probable)
Interacts with F-box protein UCC1
Cytoplasm, Peroxisome
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8GR9 | X-ray | 1.48 Å | A/B=1-460 |
| 8GRE | X-ray | 2.3 Å | A/B=1-460 |
| 8GR8 | X-ray | 2.39 Å | A/B=1-460 |
| 8GRF | X-ray | 2.53 Å | A/B=1-460 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.