P0AEN4: Cell division protein FtsL (ftsL)

Cell division protein FtsL (ftsL) is a 121-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0AEN4.

Gene
ftsL
Organism
Escherichia coli (strain K12)
Length
121 residues
Mean pLDDT
78.8
Model
AF-P0AEN4-F1 v6
Model created
1 Aug 2025
PDB structures
3

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Model confidence (pLDDT)

The mean pLDDT of this model is 78.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate36%
70 to 90Confident: backbone generally right29%
50 to 70Low: treat with caution33%
Below 50Very low: often disordered regions3%

What pLDDT means and how to read it

Function

Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. Can also mediate Zn(2+)-sensitivity probably by increasing the permeability of the inner membrane

Subunit structure

Part of a complex composed of FtsB, FtsL and FtsQ. The complex can be formed before its localization to the division site. This tripartite complex can be divided further into a subcomplex of FtsB and FtsL, which forms in the absence of FtsQ. Also interacts with FtsI, FtsN and YmgF. Homodimer in vitro. May form multimers

Subcellular location

Cell inner membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8HHFX-ray3.04 ÅL=1-121
8HHGX-ray3.1 ÅL=1-121
8HHHX-ray3.3 ÅL=1-121

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