P0CX43: Large ribosomal subunit protein uL1A (RPL1A)

Large ribosomal subunit protein uL1A (RPL1A) is a 217-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0CX43.

Gene
RPL1A
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
217 residues
Mean pLDDT
78.6
Model
AF-P0CX43-F1 v6
Model created
1 Aug 2025
PDB structures
58

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Model confidence (pLDDT)

The mean pLDDT of this model is 78.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate0%
70 to 90Confident: backbone generally right93%
50 to 70Low: treat with caution7%
Below 50Very low: often disordered regions1%

What pLDDT means and how to read it

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion…

Subunit structure

Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes). uL1 forms part of the L1 stalk…

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7ZW0EM2.4 ÅLB=1-217
8AGXEM2.4 Åw=1-217
8BN3EM2.4 ÅB=1-217
8T2XEM2.46 ÅE=1-217
8AAFEM2.5 Åw=1-217
8V83EM2.53 Åa=1-217
8AGTEM2.6 Åw=1-217
8AGVEM2.6 Åw=1-217
8AGWEM2.6 Åw=1-217
8AGZEM2.6 Åw=1-217
8HFREM2.64 ÅAs=1-217
8V87EM2.66 Åa=1-217
8AGUEM2.7 Åw=1-217
8V84EM2.7 Åa=1-217
6TB3EM2.8 ÅBT=13-216
8T3AEM2.86 ÅE=1-217
6WOOEM2.9 Åq=1-217
8T3DEM2.95 ÅE=1-217
6YLGEM3.0 Åo=1-217
8K82EM3.0 ÅL1=1-217

Showing 20 of 58 experimental structures (best resolution first).

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