P0CX49: Large ribosomal subunit protein eL18A (RPL18A)

Large ribosomal subunit protein eL18A (RPL18A) is a 186-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0CX49.

Gene
RPL18A
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
186 residues
Mean pLDDT
92.8
Model
AF-P0CX49-F1 v6
Model created
1 Aug 2025
PDB structures
226

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 92.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate81%
70 to 90Confident: backbone generally right19%
50 to 70Low: treat with caution1%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion…

Subunit structure

Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554).…

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8CCSEM1.97 ÅC=1-186
8CDREM2.04 ÅC=1-186
8CEHEM2.05 ÅC=1-186
8P8NEM2.15 ÅQP=1-186
8PFREM2.15 ÅQP=1-186
8EVTEM2.2 ÅAQ=1-186
8T2YEM2.2 ÅAQ=1-186
8P8UEM2.23 ÅQP=1-186
8CGNEM2.28 ÅC=1-186
8ZHCEM2.3 ÅLS=2-186
7UOOEM2.34 ÅQ=1-186
7V08EM2.36 ÅQ=1-186
8EVPEM2.38 ÅAQ=1-186
7TOPEM2.4 ÅAL18=1-186
7ZW0EM2.4 ÅLT=1-186
8AGXEM2.4 ÅD=1-186
8BN3EM2.4 ÅM8=2-186
8T2ZEM2.4 ÅAQ=1-186
7UQBEM2.43 ÅQ=1-186
7UQZEM2.44 ÅQ=1-186

Showing 20 of 226 experimental structures (best resolution first).

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.