P10301: Ras-related protein R-Ras (RRAS)

Ras-related protein R-Ras (RRAS) is a 218-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P10301.

Gene
RRAS
Organism
Homo sapiens
Length
218 residues
Mean pLDDT
85.6
Model
AF-P10301-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 85.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate67%
70 to 90Confident: backbone generally right12%
50 to 70Low: treat with caution13%
Below 50Very low: often disordered regions8%

What pLDDT means and how to read it

Function

GTP-binding protein with GTPase activity, likely involved in the regulation of MAPK signaling pathway and thereby controlling multiple cellular processes (PubMed:39809765). Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267). With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267)

Subunit structure

Interacts with PLCE1 (PubMed:16537651). Interacts (active GTP-bound form preferentially) with RGS14 (By similarity). Interacts with OSBPL3 (By similarity) (PubMed:16537651, PubMed:18270267, PubMed:20074548). Interacts with ZDHHC19 (PubMed:20074548)

Subcellular location

Cell membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2FN4X-ray1.65 ÅA=23-201
7S0ZX-ray2.34 ÅC/D=23-201

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