P12888: Uracil-DNA glycosylase (UNG)

Uracil-DNA glycosylase (UNG) is a 255-residue protein from Epstein-Barr virus. This is its AlphaFold structure prediction, created 3 Jul 2025. UniProt accession: P12888.

Gene
UNG
Organism
Epstein-Barr virus
Length
255 residues
Mean pLDDT
91.7
Model
AF-0000000365833933 v1
Model created
3 Jul 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 91.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate86%
70 to 90Confident: backbone generally right4%
50 to 70Low: treat with caution6%
Below 50Very low: often disordered regions4%

What pLDDT means and how to read it

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes

Subcellular location

Host nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6LYJX-ray2.1 ÅA/B=1-255
2J8XX-ray2.3 ÅA/C=25-255

More AlphaFold highlights

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