P14206: Small ribosomal subunit protein uS2 (Rpsa)

Small ribosomal subunit protein uS2 (Rpsa) is a 295-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P14206.

Gene
Rpsa
Organism
Mus musculus
Length
295 residues
Mean pLDDT
79.8
Model
AF-P14206-F1 v6
Model created
1 Aug 2025
PDB structures
10

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Model confidence (pLDDT)

The mean pLDDT of this model is 79.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate64%
70 to 90Confident: backbone generally right10%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions22%

What pLDDT means and how to read it

Function

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA (By similarity). Enables malignant tumor cells to penetrate laminin tissue and…

Subunit structure

Monomer (37LRP) and homodimer (67LR) (By similarity). Component of the small ribosomal subunit (PubMed:36517592). Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S) (PubMed:36517592). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S) (PubMed:36517592).…

Subcellular location

Cell membrane, Cytoplasm, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9H4NEM2.46 Åo2=3-216
9QOHEM2.78 Åo2=1-295
9QQPEM2.8 Åo2=1-295
7CPUEM2.82 ÅSA=1-295
7CPVEM3.03 ÅSA=1-295
9QQLEM3.09 Åo2=1-295
7LS2EM3.1 Åo2=1-295
9QWTEM3.1 Åo2=1-295
7LS1EM3.3 Åo2=1-295
9QSAEM3.4 Åo2=1-295

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