7LS2: 80S ribosome from mouse
80S ribosome from mouse bound to eEF2 (Class I). Determined by electron microscopy at 3.1 Å resolution. Released 3 Nov 2021.
- Method
- Electron microscopy
- Resolution
- 3.1 Å
- Organism
- Mus musculus
- Chains
- 85
- Atoms
- 227,130
- Mol. weight
- 3922.91 kDa
- Ligands
- ZN, GDP, MG
- Released
- 3 Nov 2021
Explore 7LS2 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7LS2 contains 575 α-helices and 598 β-strands across 80 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain A: 4 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 185 | 1 | 44 |
| α-helix | 187-189 | 3 | |
| β-strand | 191 | 1 | 44 |
| α-helix | 218-220 | 3 | |
| α-helix | 223-230 | 8 | |
| α-helix | 284-291 | 8 | |
Chain A1: 14 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 50-100 | 51 | |
| β-strand | 103-105 | 3 | 1 |
| α-helix | 106-109 | 4 | |
| β-strand | 111-116 | 6 | 2 |
| α-helix | 125-133 | 9 | |
| β-strand | 141-146 | 6 | 2 |
| α-helix | 149-157 | 9 | |
| α-helix | 159-161 | 3 | |
| β-strand | 162-165 | 4 | 2 |
| α-helix | 169-179 | 11 | |
| β-strand | 181-183 | 3 | 3 |
| β-strand | 188-190 | 3 | 3 |
| α-helix | 194-201 | 8 | |
| α-helix | 202-204 | 3 | |
| α-helix | 209-217 | 9 | |
| α-helix | 223-229 | 7 | |
| β-strand | 230 | 1 | 3 |
| α-helix | 231-232 | 2 | |
| β-strand | 233-234 | 2 | 2 |
| α-helix | 237-238 | 2 | |
| β-strand | 248 | 1 | 4 |
| α-helix | 249-251 | 3 | |
| β-strand | 255 | 1 | 4 |
| β-strand | 256-257 | 2 | 2 |
| α-helix | 262-269 | 8 | |
Chain a2: 6 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 16-18 | 3 | |
| β-strand | 20-24 | 5 | 82 |
| β-strand | 30-34 | 5 | 82 |
| α-helix | 35-39 | 5 | |
| α-helix | 41-44 | 4 | |
| α-helix | 63-66 | 4 | |
| α-helix | 69-72 | 4 | |
| α-helix | 84-114 | 31 | |
Chain A3: 9 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 12-13 | 2 | 60 |
| α-helix | 15-17 | 3 | |
| β-strand | 20-21 | 2 | 60 |
| β-strand | 25 | 1 | 61 |
| α-helix | 26-29 | 4 | |
| α-helix | 30-32 | 3 | |
| α-helix | 38-48 | 11 | |
| β-strand | 55 | 1 | 61 |
| α-helix | 61-72 | 12 | |
| α-helix | 75-77 | 3 | |
| α-helix | 81-83 | 3 | |
| β-strand | 86 | 1 | 62 |
| β-strand | 96 | 1 | 62 |
| α-helix | 101-117 | 17 | |
| α-helix | 120-127 | 8 | |
Chain B1: 14 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 56 | 1 | 18 |
| α-helix | 59-73 | 15 | |
| β-strand | 76 | 1 | 19 |
| α-helix | 78-81 | 4 | |
| α-helix | 89-101 | 13 | |
| α-helix | 103-105 | 3 | |
| α-helix | 107-121 | 15 | |
| β-strand | 137-138 | 2 | 20 |
| α-helix | 140-148 | 9 | |
| β-strand | 154-158 | 5 | 20 |
| α-helix | 165-168 | 4 | |
| α-helix | 170-177 | 8 | |
| β-strand | 181-184 | 4 | 20 |
| α-helix | 188-193 | 6 | |
| β-strand | 201-204 | 4 | 20 |
| α-helix | 209-211 | 3 | |
| α-helix | 212-222 | 11 | |
| α-helix | 223-227 | 5 | |
| α-helix | 231-235 | 5 | |
| β-strand | 238 | 1 | 19 |
| α-helix | 244-265 | 22 | |
Chain b2: 7 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-9 | 4 | |
| α-helix | 14-36 | 23 | |
| α-helix | 41-73 | 33 | |
| α-helix | 89-93 | 5 | |
| α-helix | 95-96 | 2 | |
| α-helix | 97-101 | 5 | |
| α-helix | 105-113 | 9 | |
| β-strand | 119-121 | 3 | 57 |
Chain B3: 7 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 11-25 | 15 | |
| α-helix | 52-66 | 15 | |
| β-strand | 70 | 1 | 70 |
| α-helix | 72-79 | 8 | |
| β-strand | 81-83 | 3 | 71 |
| α-helix | 89-90 | 2 | |
| β-strand | 91-93 | 3 | 71 |
| α-helix | 94-96 | 3 | |
| α-helix | 97-109 | 13 | |
| β-strand | 113-115 | 3 | 70 |
| β-strand | 121-123 | 3 | 70 |
| α-helix | 125-143 | 19 | |
Chain C1: 6 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 3-11 | 9 | 29 |
| β-strand | 17-20 | 4 | 30 |
| β-strand | 24-29 | 6 | 30 |
| β-strand | 32-37 | 6 | 30 |
| β-strand | 44-48 | 5 | 29 |
| β-strand | 54-62 | 9 | 29 |
| α-helix | 64-85 | 22 | |
| β-strand | 88-95 | 8 | 31 |
| α-helix | 100-101 | 2 | |
| β-strand | 102-106 | 5 | 32 |
| β-strand | 111-115 | 5 | 32 |
| α-helix | 117-119 | 3 | |
| β-strand | 124-127 | 4 | 32 |
| α-helix | 128-129 | 2 | |
| β-strand | 133-136 | 4 | 31 |
| β-strand | 143-148 | 6 | 31 |
| α-helix | 151-164 | 14 | |
| α-helix | 172-175 | 4 | |
| β-strand | 178-185 | 8 | 31 |
72 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 60S ribosomal protein L7 | A1 | protein | 270 | Mus musculus | P14148 (AlphaFold model) |
| 60S ribosomal protein L7a | B1 | protein | 266 | Mus musculus | P12970 (AlphaFold model) |
| 60S ribosomal protein L9 | C1 | protein | 192 | Mus musculus | P51410 (AlphaFold model) |
| 60S ribosomal protein L10-like | D1 | protein | 214 | Mus musculus | P86048 (AlphaFold model) |
| 60S ribosomal protein L11 | E1 | protein | 178 | Mus musculus | Q9CXW4 |
| 60S ribosomal protein L13 | F1 | protein | 211 | Mus musculus | P47963 |
| 60S ribosomal protein L14 | G1 | protein | 217 | Mus musculus | Q9CR57 |
| 60S ribosomal protein L15 | H1 | protein | 204 | Mus musculus | Q9CZM2 |
| 28S rRNA | A2 | RNA | 4731 | Mus musculus | |
| 5S rRNA | B2 | RNA | 121 | Mus musculus | |
| 5.8S rRNA | C2 | RNA | 156 | Mus musculus | |
| 60S ribosomal protein L8 | D2 | protein | 257 | Mus musculus | P62918 |
73 more molecules are not listed.
Sequence of entity 1 (A1), FASTA
>7LS2_1 60S ribosomal protein L7 (chains A1)
MEAVPEKKKKVATVPGTLKKKVPAGPKTLKKKVPAVPETLKKKRRNFAELKVKRLRKKFA
LKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGI
NGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRG
YGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRG
GMKKKTTHFVEGGDAGNREDQINRLIRRMN
Sequence of entity 2 (B1), FASTA
>7LS2_2 60S ribosomal protein L7a (chains B1)
MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRY
IRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEK
KAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVP
YCIIKGKARLGHLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGN
VLGPKSVARIAKLEKAKAKELATKLG
Sequence of entity 3 (C1), FASTA
>7LS2_3 60S ribosomal protein L9 (chains C1)
MKTILSNQTVDIPENVEITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRTGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE
Sequence of entity 4 (D1), FASTA
>7LS2_4 60S ribosomal protein L10-like (chains D1)
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL
SSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG
KPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE
FEDKVAAKRLIPDGCGVKYIPERGPLDKWRALHS
Sequence of entity 5 (E1), FASTA
>7LS2_5 60S ribosomal protein L11 (chains E1)
MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSF
GIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYD
PSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK
Sequence of entity 6 (F1), FASTA
>7LS2_6 60S ribosomal protein L13 (chains F1)
MAPSRNGMILKPHFHKDWQQRVDTWFNQPARKIRRRKARQAKARRIAPRPASGPIRPIVR
CPTVRYHTKVRAGRGFSLEELRVAGIHKKVARTIGISVDPRRRNKSTESLQANVQRLKEY
RSKLILFPRKPSAPKKGDSSAEELKLATQLTGPVMPIRNVYKKEKARVITEEEKNFKAFA
SLRMARANARLFGIRAKRAKEAAEQDVEKKK
Sequence of entity 7 (G1), FASTA
>7LS2_7 60S ribosomal protein L14 (chains G1)
MVFRRYVEVGRVAYISFGPHAGKLVAIVDVIDQNRALVDGPCTRVRRQAMPFKCMQLTDF
ILKFPHSARQKYVRKAWEKADINTKWAATRWAKKIDARERKAKMTDFDRFKVMKAKKMRN
RIIKTEVKKLQRAAILKASPKKAAVAKAAIAAAAAAAAAKAKVPAKKATGPGKKAAGQKA
PAQKAAGQKAAPPAKGQKGQKTPAQKAPAPKAAGKKA
Sequence of entity 8 (H1), FASTA
>7LS2_8 60S ribosomal protein L15 (chains H1)
MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYV
IYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYW
VGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKF
HHTIGGSRRAAWRRRNTLQLHRYR
Sequence of entity 9 (A2), FASTA
>7LS2_9 28S rRNA (chains A2)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCGCGCGUCGCGGCGUGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCUCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGC
GCGCGUCCGGCCGUGCCGGUGGUCCGGCGGAUCUUUCCCGCUCCCCGUUCCUCCCGACCC
CUCCACCCGCGCGUCGUUCCCCUCUUCCUCCCCGCGUCCGGCGCCUCCGGCGGCGGGCGC
GGGGGGUGGUGUGGUGGUGGCGCGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCGC
CCCCGGCCGGCGACCGGCCGCCGCCGGGCGCACUUCCACCGUGGCGGUGCGCCGCGACCG
GCUCCGGGACGGCCGGGAAGGCCCGGUGGGGAAGGUGGCUCGGGGGGGGCGGCGCGUCUC
AGGGCGCGCCGAACCACCUCACCCCGAGUGUUACAGCCCUCCGGCCGCGCUUUUCGCCGA
AUCCCGGGGCCGAGGAAGCCAGAUACCCGUCGCCGCGCUCUCCCUCUCCCCCCGUCCGCC
UCCCGGGCGGGCGUGGGGGUGGGGGCCGGGCCGCCCCUCCCACGGCGCGACCGCUCUCCC
ACCCCCCUCCGUCGCCUCUCUCGGGGCCCGGUGGGGGGCGGGGCGGACUGUCCCCAGUGC
GCCCCGGGCGUCGUCGCGCCGUCGGGUCCCGGGGGGACCGUCGGUCACGCGUCUCCCGAC
GAAGCCGAGCGCACGGGGUCGGCGGCGAUGUCGGCUACCCACCCGACCCGUCUUGAAACA
CGGACCAAGGAGUCUAACGCGUGCGCGAGUCAGGGGCUCGUCCGAAAGCCGCCGUGGCGC
AAUGAAGGUGAAGGGCCCCGCCCGGGGGCCCGAGGUGGGAUCCCGAGGCCUCUCCAGUCC
GCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCACGAGCGU
ACGCGUUAGGACCCGAAAGAUGGUGAACUAUGCUUGGGCAGGGCGAAGCCAGAGGAAACU
CUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGGUAUAGGGG
CGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCAGGAUAGCU
GGCGCUCUCGCUCCCGACGUACGCAGUUUUAUCCGGUAAAGCGAAUGAUUAGAGGUCUUG
GGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUAAGAAGCCCGGCUCGCUG
GCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUUUUGGUAAGCAGAACUGG
CGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCCGACGCUCAUCAGACCCC
AGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUA
AGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAAAAUGGAUGGCGCUGGAG
CGUCGGGCCCAUACCCGGCCGUCGCCGGCAGUCGGAACGGAACGGGACGGGAGCGGCCGC
GGGUGCGCGUCUCUCGGGGUCGGGGGUGCGUGGCGGGGGCCCGUCCCCCGCCUCCCCUCC
GCGCGCCGGGUUCGCCCCCGCGGCGUCGGGCCCCGCGGAGCCUACGCCGCGACGAGUAGG
AGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGCAGGU
GCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGGAGAA
GGGUUCCAUGUGAACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGAGUGC
CGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGCCCUCGGCCGAUCGAAAGGGAGUCGGGU
UCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCGGUAACG
CGACCGAUCCCGGAGAAGCCGGCGGGAGCCUCGGGGAGAGUUCUCUUUUCUUUGUGAAGG
GCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCGUCGC
GGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGGUGUA
AAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUCUGGC
AUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAUAAGG
AUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGGGCGCGAAGCGGGGCUGGGCGCGCGCCG
CGGCUGGACGAGGCGCCGCCGCCCUCUCCCACGUCCGGGGAGACCCCCCGUCCUUUCCGC
CCGGGCCCGCCCUCCCCUCUUCCCCGCGGGGCCCCGUCGUCCCCCGCGUCGUCGCCACCU
CUCUUCCCCCCUCCUUCUUCCCGUCGGGGGGCGGGUCGGGGGUCGGCGCGCGGCGCGGGC
UCCGGGGCGGCGGGUCCAACCCCGCGGGGGUUCCGGAGCGGGAGGAACCAGCGGUCCCCG
GUGGGGCGGGGGGCCCGGACACUCGGGGGGCCGGCGGCGGCGGCGACUCUGGACGCGAGC
CGGGCCCUUCCCGUGGAUCGCCUCAGCUGCGGCGGGCGUCGCGGCCGCUCCCGGGGAGCC
CGGCGGGUGCCGGCGCGGGUCCCCUCCCCGCGGGGCCUCGCUCCACCCCCCCAUCGCCUC
UCCCGAGGUGCGUGGCGGGGGCGGGCGGGCGUGUCCCGCGCGUGUGGGGGGAACCUCCGC
GUCGGUGUUCCCCCGCCGGGUCCGCCCCCCGGGCCGCGGUUUUCCGCGCGGCGCCCCCGC
CUCGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUU
AAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCC
AGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAAC
UAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGA
UGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGG
CUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUG
AAGAGACAUGAGAGGUGUAGAAUAAGUGGGAGGCCCCCGGCGCCCGGCCCCGUCCUCGCG
UCGGGGUCGGGGCACGCCGGCCUCGCGGGCCGCCGGUGAAAUACCACUACUCUCAUCGUU
UUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUCUCGCUUCUGGCGCCA
AGCGUCCGUCCCGCGCGUGCGGGCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGG
AGUUUGACUGGGGCGGUACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAG
GGAGGACAGAAACCUCCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAG
UACGAAUACAGACCGUGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUGGGUUUUAAGC
AGGAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAG
CGACGUCGCUUUUUGAUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCAC
CAAGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAG
ACAGGUUAGUUUUACCCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGA
GAGGAACCGCAGGUUCAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAA
GCUACCAUCUGUGGGAUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAAC
GAUACGGCAGCGCCGAGGAGCCUCGGUUGGCCCCGGAUAGCCGGGUCCCCGUCCGUCCCC
GCUCGGCGGGGUCCCCGCGUCGUCCCCGCGGCGGCGCGGGGUCUCCCCCCGCCGGGCGUC
GGGACCGGGGUCCGGUGCGGAGAGCCGUUCGUCUUGGGAAACGGGGUGCGGCCGGAAAGG
GGGCCGCCCUCUCGCCCGUCACGUUGACGCACGUUCGUGUGGAACCUGGCGCUAAACCAU
UCGUAGACGACCUGCUUCUGGGUCGGGGUUUCGUACGUAGCAGAGCAGCUCCCUCGCUGC
GAUCUAUUGAAAGUCAGCCCUCGACACAAGGGUUUGUCUCUGCGGGCUUUC
Sequence of entity 10 (B2), FASTA
>7LS2_10 5S rRNA (chains B2)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
U
Sequence of entity 11 (C2), FASTA
>7LS2_11 5.8S rRNA (chains C2)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCU
Sequence of entity 12 (D2), FASTA
>7LS2_12 60S ribosomal protein L8 (chains D2)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 7 |
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 1 |
| MG | Magnesium ion | Mg | 1 |
Primary citation
Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance. Smith, P.R., Loerch, S., Kunder, N. et al. Nat Commun (2021) 12:6789-6789. DOI 10.1038/s41467-021-27160-4 · PubMed
Other PDB entries of the same protein (UniProt P14148 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9H4N 2.46 Å, RPL13 (eL13)-mutant 80S ribosome from mouse
- 31FX 2.54 Å, Mouse 80S ribosome, sgRNA control
- 31FY 2.57 Å, Mouse 80S ribosome, Gm10076 KO
- 9KDT 2.63 Å, Cryo-EM structure of 80S ribosome
- 9KDW 2.67 Å, Cryo-EM structure of 80S ribosome
- 9QOH 2.78 Å, Mouse Ribosome POST translocation state
- 9QQP 2.8 Å, Mouse Ribosome rotated-2 PRE state
- 7CPU 2.82 Å, Cryo-EM structure of 80S ribosome from mouse kidney
- 31FZ 2.89 Å, Mouse 80S ribosome, eL41 KO
- 9KDU 2.96 Å, Cryo-EM structure of 80S ribosome
- 7CPV 3.03 Å, Cryo-EM structure of 80S ribosome from mouse testis
- 9QQL 3.09 Å, Mouse RPS15 P131 Mutant Ribosome POST translocation state
Browse structure collections
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