Large ribosomal subunit protein eL8A (RPL8A) is a 256-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P17076.
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The mean pLDDT of this model is 91.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 80% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion…
Component of the large ribosomal subunit (LSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554)
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8CCS | EM | 1.97 Å | KK=1-256 |
| 8CDR | EM | 2.04 Å | KK=1-256 |
| 8CEH | EM | 2.05 Å | KK=1-256 |
| 8P8N | EM | 2.15 Å | LL=1-256 |
| 8PFR | EM | 2.15 Å | LL=1-256 |
| 8EVT | EM | 2.2 Å | AG=1-256 |
| 8T2Y | EM | 2.2 Å | AG=1-256 |
| 8P8U | EM | 2.23 Å | LL=1-256 |
| 8CGN | EM | 2.28 Å | KK=1-256 |
| 8ZHC | EM | 2.3 Å | LJ=24-256 |
| 7UOO | EM | 2.34 Å | G=1-256 |
| 7V08 | EM | 2.36 Å | G=1-256 |
| 8EVP | EM | 2.38 Å | AG=1-256 |
| 7TOP | EM | 2.4 Å | AL08=1-256 |
| 7ZW0 | EM | 2.4 Å | LK=1-256 |
| 8AGX | EM | 2.4 Å | p=1-256 |
| 8BN3 | EM | 2.4 Å | L8=24-256 |
| 8T2Z | EM | 2.4 Å | AG=1-256 |
| 7UQB | EM | 2.43 Å | G=1-256 |
| 7UQZ | EM | 2.44 Å | G=1-256 |
Showing 20 of 229 experimental structures (best resolution first).
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