Troponin C, slow skeletal and cardiac muscles (Tnnc1) is a 161-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P19123.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 79.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 1% |
| 70 to 90 | Confident: backbone generally right | 86% |
| 50 to 70 | Low: treat with caution | 10% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9MOW | EM | 4.9 Å | H=1-161 |
| 9MOP | EM | 5.0 Å | G=1-161 |
| 9MOM | EM | 5.1 Å | H=1-161 |
| 9MO7 | EM | 5.2 Å | G=1-161 |
| 9MO8 | EM | 5.2 Å | H=1-161 |
| 9MOL | EM | 5.2 Å | H=1-161 |
| 9MON | EM | 5.2 Å | H=1-161 |
| 9MOO | EM | 5.2 Å | G=1-161 |
| 9MOX | EM | 5.2 Å | G=1-161 |
| 9MO4 | EM | 5.3 Å | G=1-161 |
| 9MO5 | EM | 5.3 Å | G=1-161 |
| 9MO6 | EM | 5.3 Å | G=1-161 |
| 9MOA | EM | 5.4 Å | G=1-161 |
| 9MOI | EM | 5.4 Å | G=1-161 |
| 9MOB | EM | 5.5 Å | H=1-161 |
| 9MO9 | EM | 5.6 Å | G=1-161 |
| 9MOC | EM | 5.6 Å | H=1-161 |
| 9MOK | EM | 5.6 Å | H=1-161 |
| 9MOU | EM | 5.6 Å | H=1-161 |
| 9MOD | EM | 5.7 Å | H=1-161 |
Showing 20 of 22 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.