Voltage-dependent L-type calcium channel subunit beta-1 (CACNB1) is a 524-residue protein from Oryctolagus cuniculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P19517.
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The mean pLDDT of this model is 72.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 46% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 33% |
What pLDDT means and how to read it
Regulatory subunit of L-type calcium channels (PubMed:7509046). Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (PubMed:7509046). Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (By similarity)
Regulatory subunit of L-type calcium channels that consist of a pore-forming alpha subunit and auxiliary beta, gamma and delta subunits (PubMed:27580036, PubMed:7509046). Interacts with CACNA1A, CACNA1B, CACNA1C and CACNA1S (PubMed:7509046). Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1…
Cell membrane, sarcolemma, Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6JPA | EM | 2.6 Å | B=80-524, C=1-524 |
| 6JP8 | EM | 2.7 Å | B/C=80-524 |
| 6JP5 | EM | 2.9 Å | B/C=80-524 |
| 6JPB | EM | 2.9 Å | B=80-524, C=1-524 |
| 5GJV | EM | 3.6 Å | B=80-174, C=265-463 |
| 5GJW | EM | 3.9 Å | B=80-174, C=265-463 |
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