ATP-dependent RNA helicase DBP5 (DBP5) is a 482-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P20449.
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The mean pLDDT of this model is 82.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 60% |
| 70 to 90 | Confident: backbone generally right | 21% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. Contributes to the blocking of bulk poly(A)+ mRNA export in ethanol-stressed cells. May also be involved in early transcription
Associates with the nuclear pore complex. Interacts with NUP159, GLE1, GFD1 and ZDS1. The interaction with NUP159 is necessary for the association to the nuclear pore complex. Also interacts with the TFIIH complex subunits TFB1, TFB2 and RAD3
Cytoplasm, Nucleus, nuclear pore complex, Nucleus membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3PEY | X-ray | 1.4 Å | A=91-482 |
| 3PEW | X-ray | 1.5 Å | A=91-482 |
| 3GFP | X-ray | 1.8 Å | A=296-482 |
| 5ELX | X-ray | 1.81 Å | A=91-481 |
| 3PEV | X-ray | 2.5 Å | A=297-482 |
| 3PEU | X-ray | 2.6 Å | A=297-482 |
| 3RRM | X-ray | 2.88 Å | A=91-482 |
| 3RRN | X-ray | 4.0 Å | A=91-482 |
| 2KBE | NMR | A=71-296 | |
| 2KBF | NMR | A=296-482 |
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