Duffy receptor (PVDR) is a 1070-residue protein from Plasmodium vivax (strain Salvador I). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P22290.
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The mean pLDDT of this model is 57.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 25% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 57% |
What pLDDT means and how to read it
Binds to the human erythrocyte Duffy blood group determinant (ACKR1)
Homodimer; dimerization (via PvRII region) is promoted by the interaction with human ACKR1 (PubMed:21743458, PubMed:24415938). Interacts (via PvRII region) with human ACKR1 (via N-terminal extracellular domain) (PubMed:10570199, PubMed:11279211, PubMed:15720551, PubMed:16024106, PubMed:21743458, PubMed:24415938, PubMed:8879225)
Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9EZE | X-ray | 1.55 Å | A/D=211-508 |
| 3RRC | X-ray | 1.95 Å | A/B=211-525 |
| 4NUU | X-ray | 1.95 Å | A/B=211-525 |
| 4YFS | X-ray | 2.1 Å | A=198-521 |
| 8A44 | X-ray | 2.49 Å | A=215-508 |
| 4NUV | X-ray | 2.6 Å | A/B=211-525 |
| 6OAN | X-ray | 2.9 Å | A/C=211-525 |
| 6R2S | X-ray | 3.04 Å | C=211-508 |
| 6OAO | X-ray | 3.5 Å | A/C/E/G/I/K=211-525 |
| 5F3J | X-ray | 4.0 Å | A/B=211-525 |
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