P22621: Apical membrane antigen 1 (AMA-1)

Apical membrane antigen 1 (AMA-1) is a 622-residue protein from Plasmodium falciparum (isolate FC27 / Papua New Guinea). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P22621.

Gene
AMA-1
Organism
Plasmodium falciparum (isolate FC27 / Papua New Guinea)
Length
622 residues
Mean pLDDT
75.6
Model
AF-P22621-F1 v6
Model created
1 Aug 2025
PDB structures
5

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Model confidence (pLDDT)

The mean pLDDT of this model is 75.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate48%
70 to 90Confident: backbone generally right20%
50 to 70Low: treat with caution7%
Below 50Very low: often disordered regions25%

What pLDDT means and how to read it

Function

Involved in parasite invasion of erythrocytes

Subcellular location

Membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2Q8BX-ray2.3 ÅA=104-438
2Q8AX-ray2.4 ÅA=104-438
9BJHX-ray2.8 ÅA/B=104-438
9BJGX-ray2.9 ÅA=104-438
1YXENMRA=309-436

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