P25443: Small ribosomal subunit protein uS5 (RPS2)

Small ribosomal subunit protein uS5 (RPS2) is a 254-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P25443.

Gene
RPS2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
254 residues
Mean pLDDT
88.6
Model
AF-P25443-F1 v6
Model created
1 Aug 2025
PDB structures
147

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Model confidence (pLDDT)

The mean pLDDT of this model is 88.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate81%
70 to 90Confident: backbone generally right4%
50 to 70Low: treat with caution11%
Below 50Very low: often disordered regions4%

What pLDDT means and how to read it

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion…

Subunit structure

Component of the small ribosomal subunit (SSU). Mature yeast ribosomes consist of a small (40S) and a large (60S) subunit. The 40S small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 different proteins (encoded by 57 genes). The large 60S subunit contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554).…

Subcellular location

Cytoplasm, Nucleus, nucleolus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8CCSEM1.97 Åf=1-254
8CDREM2.04 Åf=1-254
8CEHEM2.05 Åf=1-254
8T2YEM2.2 ÅBC=1-254
8CGNEM2.28 Åf=1-254
8ZHCEM2.3 ÅSR=34-250
7ZW0EM2.4 ÅsR=1-254
8BN3EM2.4 ÅS2=34-250
8T2ZEM2.4 ÅBC=1-254
8T2XEM2.46 ÅBC=1-254
8CIVEM2.47 Åf=1-254
7ZUXEM2.5 ÅDC=34-249
8CG8EM2.57 Åf=1-254
6T4QEM2.6 ÅSC=34-249
8ZHBEM2.6 ÅSR=34-250
7MPJEM2.7 ÅBC=34-250
8C01EM2.7 ÅR=1-254
8ZGREM2.7 ÅSR=34-250
8ZH3EM2.7 ÅSR=34-250
8CF5EM2.71 Åf=1-254

Showing 20 of 147 experimental structures (best resolution first).

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