Adenosine receptor A1 (ADORA1) is a 326-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P30542.
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The mean pLDDT of this model is 92.4 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 83% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Receptor for adenosine (PubMed:29925945). The activity of this receptor is mediated by G proteins such as GNAI2 which inhibit adenylyl cyclase
Interacts with GNAI2
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5UEN | X-ray | 3.2 Å | A/B=2-211, A/B=228-311 |
| 7LD3 | EM | 3.2 Å | R=2-326 |
| 5N2S | X-ray | 3.3 Å | A=4-316 |
| 7LD4 | EM | 3.3 Å | R=2-326 |
| 6D9H | EM | 3.6 Å | R=2-326 |
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