Maxadilan is a 86-residue protein from Lutzomyia longipalpis. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P30659.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 74.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 1% |
| 70 to 90 | Confident: backbone generally right | 62% |
| 50 to 70 | Low: treat with caution | 36% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Potent vasodilator (PubMed:1730635, PubMed:2040631, PubMed:33715378). Activates mammalian ADCYAP1R1, a PAC1 receptor, and induces cAMP accumulation in host cells (PubMed:10438479, PubMed:12453189, PubMed:32047270, PubMed:33715378, PubMed:8995389, PubMed:12911520). Causes the development of erythema following superficial injection into the rabbit or human skin (PubMed:10438479, PubMed:1730635, PubMed:2040631). Influences adaptive immune responses mediated by host dendritic cells (PubMed:18523295). Reduces surface expression of CD80 on host dendritic cells stimulated with lipopolysaccharides (LPS) and induces concomitant increase in CD86 expression on a subpopulation of these cells…
Interacts with human ADCYAP1R1
Secreted
Compare the prediction with experimentally determined structures of the same protein:
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.