Lipocalin-1 (LCN1) is a 176-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P31025.
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The mean pLDDT of this model is 88.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 72% |
| 70 to 90 | Confident: backbone generally right | 14% |
| 50 to 70 | Low: treat with caution | 14% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket
Predominantly monomer (PubMed:17869594). May form homodimer (PubMed:17869594). Interacts with LMBR1L; this interaction mediates the endocytosis of LCN1 (PubMed:11287427, PubMed:12591932)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1XKI | X-ray | 1.8 Å | A=23-176 |
| 4QAF | X-ray | 1.8 Å | A/B=23-174 |
| 3EYC | X-ray | 2.6 Å | A/B/C/D=23-176 |
| 5T43 | NMR | A=19-176 |
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