26S proteasome regulatory subunit RPN12 (RPN12) is a 274-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P32496.
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The mean pLDDT of this model is 74.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 68% |
| 50 to 70 | Low: treat with caution | 29% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3JCK | EM | 3.5 Å | H=1-274 |
| 9CGC | EM | 3.61 Å | T=1-274 |
| 6J2Q | EM | 3.8 Å | T=1-274 |
| 6J2X | EM | 3.8 Å | T=1-274 |
| 5MPD | EM | 4.1 Å | T=1-274 |
| 6FVT | EM | 4.1 Å | T=7-272 |
| 5WVK | EM | 4.2 Å | T=1-274 |
| 5MPE | EM | 4.5 Å | T=1-274 |
| 6FVU | EM | 4.5 Å | T=7-272 |
| 6FVW | EM | 4.5 Å | T=7-272 |
| 6J30 | EM | 4.5 Å | T=1-274 |
| 3JCP | EM | 4.6 Å | T=1-274 |
| 3JCO | EM | 4.8 Å | T=1-274 |
| 6FVX | EM | 4.9 Å | T=7-272 |
| 6FVV | EM | 5.4 Å | T=7-272 |
| 7QO5 | EM | 6.0 Å | T=1-274 |
| 6FVY | EM | 6.1 Å | T=7-272 |
| 7QO3 | EM | 6.1 Å | T=1-274 |
| 5WVI | EM | 6.3 Å | T=1-274 |
| 6J2C | EM | 7.0 Å | T=1-274 |
Showing 20 of 29 experimental structures (best resolution first).
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